Protein

MIA_01600_1

Length
343 amino acids

Browser: contig02:1165019-1166051-

Protein function

EGGNOG:0PFPZKIN28serine threonine-protein kinase
SGD closest match:S000002266KIN28Serine/threonine-protein kinase KIN28
CGD closest match:CAL0000201956orf19.6239TFIIH complex serine/threonine-protein kinase subunit

Protein alignments

%idAln lengthE-value
MCA_03345_176.676%3430.0MCA_03345_1
A0A167EL28_9ASCO62.687%3355.82e-153TFIIH complex serine/threonine-protein kinase subunit KIN28 OS=Sugiyamaella lignohabitans GN=KIN28 PE=3 SV=1
A0A0J9X792_GEOCN61.243%3381.40e-152Similar to Saccharomyces cerevisiae YDL108W KIN28 Serine/threonine protein kinase, subunit of the transcription factor TFIIH OS=Geotrichum candidum GN=BN980_GECA04s07468g PE=3 SV=1
A0A1E3PGT5_9ASCO63.548%3103.83e-146Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_74994 PE=3 SV=1
UniRef50_Q75BH163.036%3031.25e-141ADL283Wp n=15 Tax=Dikarya TaxID=451864 RepID=Q75BH1_ASHGO
Q5AAS1_CANAL56.637%3391.45e-139TFIIH complex serine/threonine-protein kinase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6239 PE=3 SV=1
A0A060SWL2_BLAAD62.829%3048.42e-137ARAD1A05918p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A05918g PE=4 SV=1
KIN28_YEAST58.804%3012.02e-133Serine/threonine-protein kinase KIN28 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIN28 PE=1 SV=1
A0A1E4TFE6_9ASCO59.223%3098.25e-131Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2208 PE=3 SV=1
Q6CAB2_YARLI58.224%3042.39e-130YALI0D04334p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D04334g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0098

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 343

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. PIRSF000654 (ILK)
  5. cd07841 (STKc_CDK7)
  6. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd07841
  3. CDK/cyclin interfa...
  4. polypeptide substr...
  5. activation loop (A...

Protein sequence

>MIA_01600_1
MEKYPKERKVGEGTYAEVYVGRNQENGNLIAIKALKVTGFKEGLDMSAIREIKFLQEIRHRNVIELIDVFATSNSISLVL
EYLPADLEMLIKEKSLIFKPADVKSWLLMTLRGLHHCHRSFVLHRDLKPNNLLVAPDGQIKLADFGLARAMAVPREAMTP
LVVTRWYRAPELCLGARFYTGAIDIWSVGAIFAELMLRTPYLPGEDDAGQAILIFKALGTPTEQTWPGITQLDGYKGLGP
SIGKFPAPRKADLQHLFLAASDTALDLLQGMLTLCPSKRLNTEQALKSPYFVELPRATKPEDLPRKAPSAVESEGDSEER
KRKEEMRQNMINQTRERRMQTQI

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.