Protein
MIA_01597_1
Length
431 amino acids
Browser: contig02:1160452-1161810-
Protein function
| EGGNOG: | 0PGX3 | UNG1 | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) |
|---|---|---|---|
| SGD closest match: | S000004483 | UNG1 | Uracil-DNA glycosylase |
| CGD closest match: | CAL0000183494 | UNG1 | Uracil-DNA glycosylase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_03342_1 | 64.392% | 337 | 2.50e-144 | MCA_03342_1 |
| A0A060SX41_BLAAD | 56.886% | 334 | 2.69e-124 | Uracil-DNA glycosylase OS=Blastobotrys adeninivorans GN=UNG1 PE=3 SV=1 |
| UniRef50_A0A060SX41 | 56.886% | 334 | 6.63e-121 | Uracil-DNA glycosylase n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060SX41_BLAAD |
| A0A0J9X921_GEOCN | 61.765% | 306 | 4.83e-125 | Uracil-DNA glycosylase OS=Geotrichum candidum GN=UNG1 PE=3 SV=1 |
| A0A1E3PHC8_9ASCO | 55.728% | 323 | 5.19e-121 | Uracil-DNA glycosylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=UNG1 PE=3 SV=1 |
| A0A1E4TJ57_9ASCO | 61.278% | 266 | 9.15e-114 | Uracil-DNA glycosylase (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17222 PE=3 SV=1 |
| A0A161HK53_9ASCO | 60.956% | 251 | 1.00e-99 | Uracil-DNA glycosylase OS=Sugiyamaella lignohabitans GN=UNG1 PE=3 SV=1 |
| Q6CAC0_YARLI | 49.669% | 302 | 4.29e-95 | Uracil-DNA glycosylase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=UNG1 PE=3 SV=1 |
| A0A1D8PKH5_CANAL | 52.688% | 279 | 2.60e-87 | Uracil-DNA glycosylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UNG1 PE=3 SV=1 |
| UNG_YEAST | 49.815% | 271 | 1.18e-84 | Uracil-DNA glycosylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UNG1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8627
Predicted cleavage: 35
Protein family membership
- Uracil-DNA glycosylase family 1 (IPR002043)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
431
Detailed signature matches
no IPR
Unintegrated signatures
-
-
SM00987 (UDG_2_a)
-
mobidb-lite (disord...)
Residue annotation
-
ligand binding sit...
-
UGI interface cd10...
-
active site cd10027
-
catalytic site cd1...
Protein sequence
>MIA_01597_1 MPPKRPAPTLNSYFKTIPGSSKSGSAVLPPAKRQATGLTKPPTTFSKQNSLSFVKFDKAKWVASLTPEQRELLQLEIDTL EKSWLEILYPELTKPYFLNLKRFLAQEKKNKQVVFPPEADIYSWSHLTPYSKVKVVILGQDPYHNVNQAHGLAFSVKPPT PAPPSLKNMYIALTNDYPQFKKPPHNGGYLVKWAKQGVLMLNTCLTVRAHNANSHAKKGWETFTEKVLAAIARGSIDGKT AVNVHPVCFLAWGSPAGKRMDIIKPDPSIHKVLRTVHPSPLSASRGFFSAGHFRKANEFLEEKYGPGGIINWALNSDNKI DEIEEKLALGVAQKKAKAEQETDKEESKDEEKENDNHEKSLKESTHNSNEKELPESESDQKGTVSLASAEKQAESQKTDS TGETKTKETSEVLTEIKNVNETAPSTNNKKT
GO term prediction
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Cellular Component
None predicted.