MIA_01578_1

Protein

Length

373 amino acids

Protein function

EGGNOG:	0PFN4	GAL10	udp-glucose 4-epimerase
SGD closest match:	S000000223	GAL10	Bifunctional protein GAL10
CGD closest match:	CAL0000174041	GAL10	Bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase

Protein alignments

	%id	Aln length	E-value
MCA_03136_1	81.918%	365	0.0	MCA_03136_1
A0A060TAT4_BLAAD	75.691%	362	0.0	ARAD1B03300p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B03300g PE=3 SV=1
A0A0J9XE28_GEOCN	70.109%	368	1.08e-173	Similar to Saccharomyces cerevisiae YBR019C GAL10 UDP-glucose-4-epimerase OS=Geotrichum candidum GN=BN980_GECA10s00615g PE=3 SV=1
Q6C4H2_YARLI	68.207%	368	1.05e-166	YALI0E26829p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26829g PE=3 SV=1
A0A1E3PTD8_9ASCO	64.932%	365	9.11e-157	UDP-glucose 4-epimerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49320 PE=3 SV=1
UniRef50_C4Y260	64.507%	355	6.54e-151	Uncharacterized protein n=3 Tax=Saccharomycetales TaxID=4892 RepID=C4Y260_CLAL4
A0A1D8PCN0_CANAL	63.611%	360	5.20e-150	Bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GAL10 PE=4 SV=1
GAL10_YEAST	63.456%	353	8.31e-144	Bifunctional protein GAL10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAL10 PE=1 SV=2
A0A1E4TIH2_9ASCO	58.333%	360	3.18e-128	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147300 PE=3 SV=1
A0A167CCX0_9ASCO	75.455%	220	1.87e-113	Bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase OS=Sugiyamaella lignohabitans GN=GAL10 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0138

Protein family membership

UDP-glucose 4-epimerase (IPR005886)

Domains and repeats

Domain
1 - 357
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 373

Detailed signature matches

IPR005886

UDP-glucose 4-epimerase
1. TIGR01179
  
  6 - 355
  
  TIGRFAMs
  TIGR01179 (TIGR01179)
2. cd05247 (UDP_G4E_1_...)
  
  6 - 351
  
  CDD
  cd05247 (UDP_G4E_1_SDR_e)
IPR016040

NAD(P)-binding domain
1. PF16363 (GDP_Man_Dehyd)
  
  7 - 345
  
  Pfam
  PF16363 (GDP_Man_Dehyd)
2. SSF51735 (NAD(P)-bi...)
  
  1 - 357
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)

no IPR

Unintegrated signatures

Coil

33 - 53

COILS
Coil (Coil)
G3DSA:3.40.50...

1 - 189

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
G3DSA:3.90.25.10

190 - 361

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)

Residue annotation

NAD binding site c...

10G

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

12A

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

13G

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

14Y

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

15I

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

34D

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

35N

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

36L

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

37S

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

38N

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

39S

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

61V

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

62D

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

63I

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

85F

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

86A

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

87G

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

89K

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

104Q

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

127S

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

128S

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

129S

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

157Y

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

161K

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

185Y

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

186F

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)

188P

NAD binding site
10G, 12A, 13G, 14Y, 15I, 34D, 35N, 36L, 37S, 38N, 39S, 61V, 62D, 63I, 85F, 86A, 87G, 89K, 104Q, 127S, 128S, 129S, 157Y, 161K, 185Y, 186F, 188P
CDD
cd05247 (UDP_G4E_1_SDR_e)
homodimer interfac...

95T

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

97I

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

98P

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

99L

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

102Y

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

103D

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

106V

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

107G

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

110I

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

111N

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

113T

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

114K

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

117K

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

156P

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

159R

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

163F

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

166H

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

167I

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

169R

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

170D

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

171Y

homodimer interface
95T, 97I, 98P, 99L, 102Y, 103D, 106V, 107G, 110I, 111N, 113T, 114K, 117K, 156P, 159R, 163F, 166H, 167I, 169R, 170D, 171Y
CDD
cd05247 (UDP_G4E_1_SDR_e)
active site cd05247

105N

active site
105N, 129S, 157Y, 161K
CDD
cd05247 (UDP_G4E_1_SDR_e)

129S

active site
105N, 129S, 157Y, 161K
CDD
cd05247 (UDP_G4E_1_SDR_e)

157Y

active site
105N, 129S, 157Y, 161K
CDD
cd05247 (UDP_G4E_1_SDR_e)

161K

active site
105N, 129S, 157Y, 161K
CDD
cd05247 (UDP_G4E_1_SDR_e)
substrate binding ...

129S

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

130A

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

131T

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

157Y

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

185Y

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

186F

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

187N

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

206N

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

207N

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

208L

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

223L

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

224Q

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

225V

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

226F

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

237P

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

239R

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

241Y

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

290V

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

313R

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

316D

substrate binding site
129S, 130A, 131T, 157Y, 185Y, 186F, 187N, 206N, 207N, 208L, 223L, 224Q, 225V, 226F, 237P, 239R, 241Y, 290V, 313R, 316D
CDD
cd05247 (UDP_G4E_1_SDR_e)

Protein sequence

>MIA_01578_1
MSKEYVLVTGGAGYIGSHTVVALLEAGRNVVVVDNLSNSSEEALERIKQITKVDDIPFFQVDIRDAPGLEKVFDAYPTIT
SVLHFAGLKAVGESTQIPLEYYDQNVGGTINLTKVLKARGVKKFVFSSSATVYGDATRYENMIPIPEECPTSGESPYGRT
KLFIEHILRDYTLSIPGTYTALLRYFNPMGAHPSGLMGEDPSGIPNNLLPYLAQVASGRRRELQVFGNDYDSRDGTPIRD
YIHVLDLAQGHLAALQKLEEVEAEEKAAAEAPSKGFCREWNLGTGHGSTVLEVISAFSKAVGKPLPYRIVGRRAGDVLDL
TAKPTRANTELKWKAELSMDQACEDLWNWTKKNPYGYSNKPDATDETPASISA

GO term prediction

Biological Process

GO:0006012 galactose metabolic process

Molecular Function

GO:0003978 UDP-glucose 4-epimerase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features