MCA_03136_1

Protein

Length

372 amino acids

Gene name: GAL10

Description: Bifunctional protein GAL10

Browser: contigB:3463785-3464904+

RNA-seq: read pairs 6067, FPKM 201.0, percentile rank 88.1% (100% = highest expression)

Protein function

Annotation:		GAL10	Bifunctional protein GAL10
KEGG:	K01784	galE	UDP-glucose 4-epimerase [EC:5.1.3.2]
EGGNOG:	0PFN4	GAL10	udp-glucose 4-epimerase
SGD closest match:	S000000223	GAL10	Bifunctional protein GAL10
CGD closest match:	CAL0000174041	GAL10	Bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase

Protein alignments

	%id	Aln length	E-value
MIA_01578_1	82.14%	364	0.0	MIA_01578_1
A0A060TAT4_BLAAD	74.93%	363	0.0	ARAD1B03300p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B03300g PE=3 SV=1
A0A0J9XE28_GEOCN	68.77%	365	0.0	Similar to Saccharomyces cerevisiae YBR019C GAL10 UDP-glucose-4-epimerase OS=Geotrichum candidum GN=BN980_GECA10s00615g PE=3 SV=1
Q6C4H2_YARLI	70.87%	357	7e-177	YALI0E26829p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26829g PE=3 SV=1
UniRef50_C4Y260	67.04%	355	1e-163	Uncharacterized protein n=3 Tax=Saccharomycetales TaxID=4892 RepID=C4Y260_CLAL4
A0A1E3PTD8_9ASCO	63.84%	365	2e-166	UDP-glucose 4-epimerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49320 PE=3 SV=1
A0A1D8PCN0_CANAL	64.89%	356	1e-158	Bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GAL10 PE=4 SV=1
GAL10_YEAST	60.50%	357	3e-153	Bifunctional protein GAL10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAL10 PE=1 SV=2
A0A1E4TIH2_9ASCO	57.10%	366	1e-139	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147300 PE=3 SV=1
A0A167CCX0_9ASCO	73.64%	220	1e-111	Bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase OS=Sugiyamaella lignohabitans GN=GAL10 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0149

Protein family membership

UDP-glucose 4-epimerase (IPR005886)

Domains and repeats

Domain
5 - 356
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 372

Detailed signature matches

IPR005886

UDP-glucose 4-epimerase
1. TIGR01179
  
  8 - 355
  
  TIGRFAMs
  TIGR01179 (TIGR01179)
2. cd05247 (UDP_G4E_1_...)
  
  8 - 350
  
  CDD
  cd05247 (UDP_G4E_1_SDR_e)
IPR016040

NAD(P)-binding domain
1. PF16363 (GDP_Man_Dehyd)
  
  9 - 346
  
  Pfam
  PF16363 (GDP_Man_Dehyd)
2. SSF51735 (NAD(P)-bi...)
  
  5 - 356
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)

no IPR

Unintegrated signatures

Coil

254 - 274

COILS
Coil (Coil)
G3DSA:3.40.50...

2 - 191

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
G3DSA:3.90.25.10

192 - 362

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)

Residue annotation

NAD binding site c...

12G

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

14A

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

15G

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

16Y

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

17I

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

36D

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

37N

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

38L

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

39S

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

40N

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

41S

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

63V

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

64D

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

65I

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

87F

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

88A

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

89G

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

91K

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

106Q

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

129S

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

130S

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

131S

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

159Y

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

163K

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

187Y

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

188F

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)

190P

NAD binding site
12G, 14A, 15G, 16Y, 17I, 36D, 37N, 38L, 39S, 40N, 41S, 63V, 64D, 65I, 87F, 88A, 89G, 91K, 106Q, 129S, 130S, 131S, 159Y, 163K, 187Y, 188F, 190P
CDD
cd05247 (UDP_G4E_1_SDR_e)
homodimer interfac...

97T

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

99I

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

100P

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

101L

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

104Y

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

105D

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

108V

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

109A

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

112I

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

113T

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

115L

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

116K

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

119E

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

158P

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

161R

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

165F

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

168H

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

169I

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

171R

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

172D

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)

173H

homodimer interface
97T, 99I, 100P, 101L, 104Y, 105D, 108V, 109A, 112I, 113T, 115L, 116K, 119E, 158P, 161R, 165F, 168H, 169I, 171R, 172D, 173H
CDD
cd05247 (UDP_G4E_1_SDR_e)
active site cd05247

107N

active site
107N, 131S, 159Y, 163K
CDD
cd05247 (UDP_G4E_1_SDR_e)

131S

active site
107N, 131S, 159Y, 163K
CDD
cd05247 (UDP_G4E_1_SDR_e)

159Y

active site
107N, 131S, 159Y, 163K
CDD
cd05247 (UDP_G4E_1_SDR_e)

163K

active site
107N, 131S, 159Y, 163K
CDD
cd05247 (UDP_G4E_1_SDR_e)
substrate binding ...

131S

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

132A

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

133T

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

159Y

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

187Y

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

188F

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

189N

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

208N

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

209N

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

210L

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

225L

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

226Q

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

227V

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

228F

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

239P

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

241R

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

243Y

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

291V

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

314R

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

317D

substrate binding site
131S, 132A, 133T, 159Y, 187Y, 188F, 189N, 208N, 209N, 210L, 225L, 226Q, 227V, 228F, 239P, 241R, 243Y, 291V, 314R, 317D
CDD
cd05247 (UDP_G4E_1_SDR_e)

Protein sequence

>MCA_03136_1
MTSQKEYILVTGGAGYIGSHTVVALLEAGRNVVIVDNLSNSSLVALDRIKEITKVDDIPFFQVDIRDREGLEKVFNQYPT
ITSVLHFAGLKAVGESTQIPLEYYDQNVAGTITLLKVLEAHKINTFVFSSSATVYGDATRFENMIPIPEECPTDPESPYG
RTKVFIEHILRDHSLSHPGWHTALLRYFNPMGAHPSGLIGEDPRGIPNNLLPYLAQVATGRRKELQVFGNDYPSRDGTPI
RDYIHVMDLAQGHLAALKKLEEVAKEDAKKEKLEKGFCREWNLGTGAGSTVLEVVAAFSKAVGRDLPYRICARRSGDVLD
LTAKPTRANTELNWKATLSIDEACRDLWNWSTKNPYGFSDKPDPTDDFQPSK

GO term prediction

Biological Process

GO:0006012 galactose metabolic process

Molecular Function

GO:0003978 UDP-glucose 4-epimerase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features