Protein

MIA_01530_1

Length
629 amino acids

Browser: contig02:995089-996979-

Protein function

EGGNOG:0PJ5DPGUG_02206Choline kinase
SGD closest match:S000004123CKI1Choline kinase
CGD closest match:CAL0000199671orf19.6966Bifunctional choline kinase/ethanolamine kinase

Protein alignments

%idAln lengthE-value
MCA_01014_148.529%6121.35e-176MCA_01014_1
A0A0J9XF29_GEOCN49.174%5451.02e-140Similar to Saccharomyces cerevisiae YDR147W EKI1 Ethanolamine kinase OS=Geotrichum candidum GN=BN980_GECA13s01121g PE=4 SV=1
UniRef50_A0A0J9XF2949.174%5452.09e-137Similar to Saccharomyces cerevisiae YDR147W EKI1 Ethanolamine kinase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XF29_GEOCN
A0A167F2H6_9ASCO47.458%5313.07e-130Bifunctional choline kinase/ethanolamine kinase CKI1 OS=Sugiyamaella lignohabitans GN=CKI1 PE=4 SV=1
Q6C5L9_YARLI45.250%4006.36e-99YALI0E16907p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E16907g PE=4 SV=1
A0A1E3PJ68_9ASCO45.202%3965.39e-92Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_25626 PE=4 SV=1
A0A060T9E8_BLAAD43.846%3901.16e-87ARAD1C37510p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37510g PE=4 SV=1
A0A1E4TJ26_9ASCO43.766%3931.17e-80Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11673 PE=4 SV=1
KICH_YEAST36.830%4291.94e-66Choline kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CKI1 PE=1 SV=1
A0A1D8PK80_CANAL33.107%4413.33e-63Bifunctional choline kinase/ethanolamine kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6966 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2999
Predicted cleavage: 66

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 629

Detailed signature matches

  1. Domain IPR007521
    Choline kinase, N-terminal
    1. PF04428 (Choline_kin_N)
  2. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.20...
  2. G3DSA:3.90.12...
  3. PF01633 (Choline_ki...)
  4. cd05157 (ETNK_euk)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative active si...
  3. dimer interface cd...
  4. putative substrate...

Protein sequence

>MIA_01530_1
MTPPPTAVSPVLSGKSDPITAPSPSSVSRRYSKTRGSSGSVSPSLGPVTSGISGLSLGPSNFYRSKSFGSQSSISGSGHT
SDGESGANHHPHALPKTSIFLDNRLPSEYFKQDILKIIHRLRIHRWSKYVAPEMAKDLQVTRISGALTNAVYCVAPPTYI
RDVIKMAHKASVIAGVDQHTGHPVPFAPETNAIAREEVAEAIAAASGPNTTSDDSGYVSSISVSSSAITKKVPPKLLLRV
YGPHVENLIDRQSELNVLSRLSRRHIGPKLLGIFANGRFEQFLEATTLTKDDVRDPDVSVQIAKRMRELHDLVKLEEEKE
RALGSCAFTNISKWIGPAREKLIALQKQPQYRGKNIFKEILGTETFDEFEAAIEKYKHWLEKQYSPQPNDPKALALGQEQ
IKKELVFSHNDTQYGNLLRILPPPGSPLLSPAFEHRQIVVIDFEYSGANTRGYDIVNHFCEWMSDYLSAEQPWKIHHEKY
PTRAQRRNLIQGYAEHGYSIRAKQGGSNSVFFDDDAIEAEVEALERESMNWRAAVSVHWAIWGLVQAVIDASADAKIREE
MVTPEGYKFEDATKDEGSDEDDAEEEEDAFDYVLYAKEKIDLFWGDLIKLGIFTPETYTGPYVQIANDE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016773 phosphotransferase activity, alcohol group as acceptor

Cellular Component

None predicted.