Protein
MCA_01014_1
Length
669 amino acids
Gene name: CKI1
Description: Bifunctional choline kinase/ethanolamine kinase CKI1
Browser: contigA:3220534-3222544+
RNA-seq: read pairs 4658, FPKM 85.9, percentile rank 76.4% (100% = highest expression)
Protein function
| Annotation: | CKI1 | Bifunctional choline kinase/ethanolamine kinase CKI1 | |
|---|---|---|---|
| KEGG: | K00866 | CKI1 | choline kinase [EC:2.7.1.32] |
| EGGNOG: | 0PJ5D | PGUG_02206 | Choline kinase |
| SGD closest match: | S000002554 | EKI1 | Ethanolamine kinase |
| CGD closest match: | CAL0000199671 | orf19.6966 | Bifunctional choline kinase/ethanolamine kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01530_1 | 49.00% | 602 | 0.0 | MIA_01530_1 |
| A0A0J9XF29_GEOCN | 44.75% | 581 | 7e-147 | Similar to Saccharomyces cerevisiae YDR147W EKI1 Ethanolamine kinase OS=Geotrichum candidum GN=BN980_GECA13s01121g PE=4 SV=1 |
| UniRef50_A0A0J9XF29 | 44.75% | 581 | 1e-143 | Similar to Saccharomyces cerevisiae YDR147W EKI1 Ethanolamine kinase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XF29_GEOCN |
| A0A167F2H6_9ASCO | 43.70% | 579 | 3e-142 | Bifunctional choline kinase/ethanolamine kinase CKI1 OS=Sugiyamaella lignohabitans GN=CKI1 PE=4 SV=1 |
| Q6C5L9_YARLI | 43.54% | 441 | 2e-108 | YALI0E16907p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E16907g PE=4 SV=1 |
| A0A1E3PJ68_9ASCO | 40.57% | 456 | 6e-98 | Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_25626 PE=4 SV=1 |
| A0A1D8PK80_CANAL | 30.96% | 491 | 6e-60 | Bifunctional choline kinase/ethanolamine kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6966 PE=4 SV=1 |
| A0A1E4TJ26_9ASCO | 43.35% | 233 | 2e-53 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11673 PE=4 SV=1 |
| A0A060T9E8_BLAAD | 40.41% | 292 | 4e-52 | ARAD1C37510p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37510g PE=4 SV=1 |
| EKI1_YEAST | 27.90% | 448 | 7e-46 | Ethanolamine kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EKI1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.6417
Predicted cleavage: 46
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
600
669
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
PF01633 (Choline_ki...)
-
cd05157 (ETNK_euk)
-
mobidb-lite (disord...)
Residue annotation
-
putative substrate...
-
putative active si...
-
ATP binding site c...
-
dimer interface cd...
Protein sequence
>MCA_01014_1 MSLKHRTPSSSSLDGGLGMSHLHINAPSSSTSQRRHHSRRSSNRGGSFSSLSSLSGGSEDESGLESGATANKFAKRTSAI PRCDDFFLDNTLPQEYFKQDVLKLIYKLKIPHWGRYVTKEMAKDISVDRISGALTNAVYCVSPPKYLREVIKAQLTANII GGIDQNTGLPVNTVATNDDETDATVNSSSANEPSRTTTAMKHSTSTTALFQQHHIKLPEKLLLRVYGPHVENLIDREVEL DVLARLYRRHIGPKLLGIFQNGRLEKFLNAKALTKQEIRIPEVSVQIAKRMRELHDLIQLDPVSERSKGPSVFINMDKWN VPAREKLEQIIACKQQEDPSLSAEKLVKDVLCVESYDEFERVFNKYKTWLVSQYATDKELMASNRPAPSSSSLDSMSNEK PIKNNTPTETTKPSNEKTLSETDAYKLGTVELKKQLVFAHNDTQYGNLLRILPNNKASPLMSPQYEHRQIVVIDFEYSGA NPRSFDIANHFCEWMSDYHDPQRPWAIHPDQYPTRSERLNLIQGYVEHGYTLSKSLSFDDEAIEAEVKSLEKQALLWRAC TSASWAAWGLVQAVVDIKSDLKTRQELLTKEGYKFDESKDNTASGEDETDKKSTNSSGDEVEEEEEDLFDYIAYAREKAM LFWADMLKFGIVTRDEYKGPIMEIHNDDK
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Cellular Component
None predicted.