Protein

MIA_01493_1

Length
1,969 amino acids

Browser: contig02:879124-885084-

Protein function

EGGNOG:0PHGWDNA2DNA. Replication
SGD closest match:S000001207DNA2DNA replication ATP-dependent helicase/nuclease DNA2
CGD closest match:CAL0000193143DNA2Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease

Protein alignments

%idAln lengthE-value
MCA_02481_146.649%11190.0MCA_02481_1
A0A0J9XAJ8_GEOCN41.570%11210.0Similar to Saccharomyces cerevisiae YHR164C DNA2 Tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities OS=Geotrichum candidum GN=BN980_GECA08s00164g PE=4 SV=1
UniRef50_A0A0J9XAJ841.570%11210.0Similar to Saccharomyces cerevisiae YHR164C DNA2 Tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XAJ8_GEOCN
A0A060T4V5_BLAAD38.384%10890.0ARAD1C44616p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C44616g PE=4 SV=1
Q6C3N5_YARLI36.506%10820.0YALI0E33377p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E33377g PE=4 SV=2
A0A1D8PPB3_CANAL38.338%9990.0Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DNA2 PE=4 SV=1
A0A167CWN1_9ASCO37.700%9390.0Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2 OS=Sugiyamaella lignohabitans GN=DNA2 PE=4 SV=1
DNA2_YEAST33.423%11133.08e-170DNA replication ATP-dependent helicase/nuclease DNA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DNA2 PE=1 SV=1
A0A1E3PP72_9ASCO28.455%4924.79e-39p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81704 PE=4 SV=1
A0A1E4TKE7_9ASCO28.791%4552.29e-26Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_84103 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2139

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1800 1969

Detailed signature matches

  1. Domain IPR014808
    DNA replication factor Dna2, N-terminal
    1. PF08696 (Dna2)
  2. Domain IPR022765
    Dna2/Cas4, domain of unknown function DUF83
    1. PF01930 (Cas_Cas4)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. NON_CYTOPLASM... (N...)
  3. PF13086 (AAA_11)
  4. PF13087 (AAA_12)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. mobidb-lite (disord...)

Protein sequence

>MIA_01493_1
MPPKSTKGSNKRPSKNSKKKTATLSSLSHESANSAQDSKGVVKKTRNKKSDSITAPIPKNNLATRSSSSILLSQKSANPN
CNNIAGKNEKNVLKDGINILEIIQDDLVDSYWENDTRFQKEHTLNSNVDIVRSTKRAKTSDHTVIHDPHVNNKEDEDAVQ
IRDDSVFAISPDRKLILSDSDTQGTSKSLFGISWDTKKLSMAKGVNYFVHGSFNDMNEENQIGKTDSESDYPRLKVPNIS
KNKENLVSLDKISTGSDDLEISKRSDPDSELRAKFNSFLPNNLNTNFGYNFQNDTKKSGDGIGNITSNNMPPSTCPQKSL
EKNSNINHKNLLNKEILFVKLPVNDTLKSQGEFTEIQKARRAKSDAPEFFSPTRSMESLPKKLMCSPDYLRRDVELNNRS
NETGDPDAVKIQHSLIPVLRPDSITSPIESGNINNILEENSPSPLIKSRIGLRRTKSSKLLYNTKSETHAEILNLATKLF
DSVENDNHKDLNLNGYCDTNQKESFNLLATHSSFSVNSQSSKKLNCDLKTQQKNLHNLKDIGLSKDYACNVINNSSSPTR
SDKTTSEKPSSEISSNMDNASGYESFCSSKSNEVDSNRISEDFNNDNHIPSTSQLKTTSTCSKQNEKDTKECPDMNSSSD
WDDDIDDDLIKEAFTSLSCSAKPQTLPEVNPRIPFESTSATKEDNSHFVNKTLQTSQLENLNSPYPVITPKKDNSAGNFE
EDLEDDFDEETMKELESFFVSPNTVLNGSNNNHQSKLRSAIREKNDSNTLFQTIEDVPPENKDLFPSCFDVRNLPKTRGR
VTTQSPPAIKSLLKNPDLFRYNVLSVTETETPDNFPQYDIIAIDQYERRTKIILRDQWTACPPAVNDIVHVITKPNQYQY
EKPKNLKSIYTSNNFDRDEATKNPVKNPDRYYENIIVDREHNIFIVCPDVLVIATAVAQSFSCIRKVVLQSRVKLPDGRP
SPPMVYGNMIHQLLQSCLMDSSFEKNYALKKVDELVNTNLETLFLCDINKETAVNYMKEKIPAILQWGLTFVGDTLNSNS
KIHVHGESGYDNLAVRQVIDIEESIMAPTYGIKGTIDAVANVTTARLIKKGSNTTPVKRFVPIEIKTGRRMDASHFAQIS
LYNLLIDEKYNFFSGNIRGLLVYTETGETYQVPCIPNELRDVIIARNKLATSMKNKIQPLPEPTDHKDTYCTNCEYFDAC
VLYNNVIENQTAETFGDSFEESYQSLVNSIGPQERKFFMKWDMLLAKEEGEMEGHSKELWTMISSDRENLGRCFAHVKLQ
NLVSSGGYVYNFERFSSSDGPFKIEESSISIGESVFITDEETNAVIAKGVFYGGTSSQIQIYFSSPVISPWDIDTPLNKD
LNLTHHPRVSVTTGSSLINLSKRKLRIDLDEFTSSLALARRNIIELVLQKNDSRLRNLILHDEAPSFKFKPSPYTIPGLK
EGRVSFNSDQLKAVEKVMKSDHCTLILGMPGTGKTTTIAALIDTLVSLGKSVLLASYTNSAVDNILLKIKDSGYDILRIG
RFSSVHRDVRKFLPGDIKDPEDINRFYMNPKVVASTCLGIRHWVFSKRHFDYCIIDEASQVTLPVCIGPLMLAKKFVLVG
DHYQLSPLVINSEALEGGLDISLFKYLNDKYPQSVINLEHQYRMCKEIMVLSNSLIYEGRLKCGSDQAACQYLPIPWKNV
IEAWKSENLFPKNDWLSWVLDENRKVLFLDTHNMPHAAETNKDDLLQNKTEAMLVYMIVEALCASGVSESNLGVISVYKS
QLRLINSMLKHHKKVERLTTDQFQGKDKDCVIISLVRSNSQNQIGDLLQDWRRLNVAFTRAKSKLIIIGSRKTLETASAL
NAFLKLLDDNNWSYVLPPSADKSYNIPVPEKTSRSQPLCLSQHQEINHTHNNNHNIQINPESLTRSESETLARPHQRSAA
RFGPGIGAYIGRLGPVTLNTLDELGVEPQAKGLRQSKEKKFFGTNQNHF

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.