Protein

MIA_01466_1

Length
378 amino acids

Browser: contig02:801532-802669-

Protein function

EGGNOG:0PGW3PKARCAMP-dependent protein kinase regulatory subunit
SGD closest match:S000001295BCY1cAMP-dependent protein kinase regulatory subunit
CGD closest match:CAL0000190895BCY1cAMP-dependent protein kinase regulatory subunit

Protein alignments

%idAln lengthE-value
MCA_02834_177.224%2815.28e-157MCA_02834_1
A0A0J9X6F6_GEOCN70.609%2791.19e-141cAMP-dependent protein kinase regulatory subunit OS=Geotrichum candidum GN=BN980_GECA03s06258g PE=3 SV=1
UniRef50_A0A0J9X6F670.609%2792.43e-138cAMP-dependent protein kinase regulatory subunit n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X6F6_GEOCN
A0A167FU97_9ASCO65.018%2831.06e-121cAMP-dependent protein kinase regulatory subunit OS=Sugiyamaella lignohabitans GN=BCY1 PE=3 SV=1
A0A060T9H9_BLAAD61.268%2846.20e-119cAMP-dependent protein kinase regulatory subunit OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D15356g PE=3 SV=1
KAPR_YARLI62.319%2763.15e-116cAMP-dependent protein kinase regulatory subunit OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PKAR PE=3 SV=1
A0A1E3PQM4_9ASCO56.491%2851.38e-112cAMP-dependent protein kinase regulatory subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_56492 PE=3 SV=1
KAPR_YEAST56.584%2811.18e-110cAMP-dependent protein kinase regulatory subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BCY1 PE=1 SV=4
A0A1E4THX4_9ASCO55.957%2774.95e-102Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_15843 PE=4 SV=1
KAPR_CANAL53.763%2792.54e-91cAMP-dependent protein kinase regulatory subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BCY1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0163

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 378

Detailed signature matches

  1. Family IPR012198
    cAMP-dependent protein kinase regulatory subunit
    1. PIRSF000548 (PK_reg...)
  2. Domain IPR014710
    RmlC-like jelly roll fold
    1. G3DSA:2.60.12...
  3. Domain IPR018490
    Cyclic nucleotide-binding-like
    1. SSF51206 (cAMP-bind...)
  4. Domain IPR000595
    Cyclic nucleotide-binding domain
    1. PF00027 (cNMP_binding)
    2. PS50042 (CNMP_BINDI...)
    3. SM00100 (cnmp_10)
  5. SITE IPR018488
    Cyclic nucleotide-binding, conserved site
    1. PS00888 (CNMP_BINDI...)
    2. PS00889 (CNMP_BINDI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00103 (CAMPKINASE)
  2. cd00038 (CAP_ED)
  3. mobidb-lite (disord...)

Residue annotation

  1. ligand binding sit...
  2. flexible hinge reg...
  3. ligand binding sit...
  4. flexible hinge reg...

Protein sequence

>MIA_01466_1
MALEKHPEDPTHVDSSPSSVSTAPPLANAQSLHTSSGENKSAPSSSPFSGFKSSFGGLDGGSGSAARSSRPPHSGGGSSL
FSGSYGAAGGPGIDAARQYNANRRTSVSAESLNPANFSGASIEAPTCNLTPEQLERLNKSVAKNFLFNNLDEDSLHRVLG
ALHEKRVKKDEIIIKQGDEGDYFYVVEKGSVQYIVNDEVVGKAGPGASFGELALMYNAPRAATVTALEDSVLWALDRVTF
RRILLDKTASKRKMYGEFLKDVPILSTLDTYQLSKLADALSSETYEPGQVVIKEGDVGDKFYIVENGSASVTKNSEGKVQ
DLTKGSYFGEVALLNDLPRQATVTAETKLRVVCLDKAGFQRLLGSVVDVLKAHDPTQH

GO term prediction

Biological Process

GO:0001932 regulation of protein phosphorylation

Molecular Function

GO:0008603 cAMP-dependent protein kinase regulator activity

Cellular Component

GO:0005952 cAMP-dependent protein kinase complex