Protein
MIA_01458_1
Length
1,318 amino acids
Browser: contig02:786373-790376+
Protein function
| EGGNOG: | 0PFPD | NTE1 | Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity) |
|---|---|---|---|
| SGD closest match: | S000004524 | NTE1 | Lysophospholipase NTE1 |
| CGD closest match: | CAL0000194621 | NTE1 | Lysophospholipase NTE1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_00400_1 | 68.539% | 1335 | 0.0 | MCA_00400_1 |
| A0A0J9XC16_GEOCN | 59.389% | 1374 | 0.0 | Lysophospholipase NTE1 OS=Geotrichum candidum GN=BN980_GECA08s03860g PE=3 SV=1 |
| A0A060SYP2_BLAAD | 55.782% | 1375 | 0.0 | Lysophospholipase NTE1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C02662g PE=3 SV=1 |
| UniRef50_A0A060SYP2 | 55.782% | 1375 | 0.0 | Lysophospholipase NTE1 n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A060SYP2_BLAAD |
| NTE1_YARLI | 50.000% | 1396 | 0.0 | Lysophospholipase NTE1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NTE1 PE=3 SV=1 |
| A0A167DL88_9ASCO | 55.627% | 1084 | 0.0 | Lysophospholipase NTE1 OS=Sugiyamaella lignohabitans GN=NTE1 PE=3 SV=1 |
| A0A1E4TIB0_9ASCO | 46.343% | 1340 | 0.0 | Lysophospholipase NTE1 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32062 PE=3 SV=1 |
| NTE1_CANAL | 42.723% | 1388 | 0.0 | Lysophospholipase NTE1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NTE1 PE=3 SV=1 |
| NTE1_YEAST | 49.065% | 909 | 0.0 | Lysophospholipase NTE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NTE1 PE=1 SV=1 |
| A0A1E3PLI8_9ASCO | 65.370% | 540 | 0.0 | Patatin-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45806 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0084
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1200
1318
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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-
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NON_CYTOPLASM... (N...)
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-
TRANSMEMBRANE (Tran...)
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cd00038 (CAP_ED)
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mobidb-lite (disord...)
Residue annotation
-
ligand binding sit...
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flexible hinge reg...
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ligand binding sit...
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flexible hinge reg...
Protein sequence
>MIA_01458_1 MSELSQVSDQEPSHNFLASCVWFLWRLVVHLISSITYYFFSILSKRLNVTLKVSSLLLIFILFVLIIWAIIRYRYLTTYS RLPPEVLRQEPKIDLFMDPSPDQDSKSGFSTYLEDFFSAIKIFGYLERSVFHELTRQMQTYKLEPGEVFPFNSENDFSVV VDGTLQIFTKSKDQAPARHSTGSTIIDGESYELVNEVKRGAPVSSLFTVLLLFTDSLKASSSNNDRTPQFNDSATTINQT LSQDSISDTSSSSDGLLSSPSRINLSDTPIPMDAGDAARFRFHLAGTVARAVEETTIAMIPQRTFHKLVSKYPKSTTHIV QVILTRLSRVTFQTGHHYLGLTPEIFETEIILNNSATYELPPYLHDLAVKGIHEYLEAHPDSKEESFVYLAKDKTSRYNL PKYYNSQSRQVSLQINRSHPGDLLSNVPLSRTDSSYLQPETLGIPSKRIPFSADEETEDSALRVAVTECIFKVLGLDNQG LKSDNYASVAASPMMSAVDDRYIRQHRNSFSNVITNLSKIEDLRSVHDDESTSSVNLSSQESAQIEAAKDLEIIYYKPNS ILVEQNGESHGLFFVIDGILEVGYRDKHNKYHELYTVKPGGLAGFIASVLSSRSFVEVRAKTGAYVGFLPQTTIDRICEK YPLILLGMAYMLTSSLSDLMILLDFALEWVQIPGGHMLFNEGDTADSIYIVLNGRLRSFVRDGNNLKVHSEYGQGESIGE LEVLTVSKRPYSLHAIRETELAKFPLTLFENLAKRHPSTTIEISRIVASRVLNRLGAPSLEGYEAPPSTNFRTVSIIPIT EGLPVSEFATKLFTSYKDIGHQVFSLNISTVLHKLGRNAFNKIGGLKLSGYLADLEERYQTVMYVADVSVSSPWTHTCIA QADCILLLADASAQPDVGEFERLLVTMKTTAKTELIFLHQDRYVAPGSTAKWLKNRIWVNSHHHVQMDFARDVENNQNQQ VYGRLSVIRSKVKHIQSELITKYRRRGMPVYANNYVHKSDFARLARILSGQAVGLVLGGGGARGISHIGVIRALEESGIP IDYVGGTSIGSFVGGLYARDYDLVPIYGRAKQFASRISSLWRMVFDLTYPATSYTTGHEFNRGIWKAFGESQIEDFWLRY FTNTTNITHSRMEIHQSGYAWRYIRASMSLAGLLPPLTDKGSMLLDGGYVDNLPVEQMRSWGAKYIFAVDVGSIDDTTPM TYGDTLSGLWVLMNRWNFFSRHPNVPNLAEIQQRLAYVSSVGALEKAKAAPGVYYLRPPIDNYATLDFGKFDEIYRVGTL YGHQYLYDLKRQDKFPQIPGAGLSKGKPRKALNRRNSI
GO term prediction
Biological Process
GO:0006629 lipid metabolic process
GO:0008152 metabolic process
GO:0046470 phosphatidylcholine metabolic process
Molecular Function
GO:0004622 lysophospholipase activity
Cellular Component
None predicted.