MIA_01453_1

Protein

Length

343 amino acids

Protein function

EGGNOG:	0PFE2	SRT1	Putative undecaprenyl diphosphate synthase
SGD closest match:	S000004707	SRT1	Dehydrodolichyl diphosphate synthase complex subunit SRT1
CGD closest match:	CAL0000195761	SRT1	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)

Protein alignments

	%id	Aln length	E-value
MCA_00395_1	63.848%	343	1.13e-156	MCA_00395_1
A0A0J9X2I0_GEOCN	57.455%	275	1.66e-114	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) OS=Geotrichum candidum GN=BN980_GECA01s01913g PE=3 SV=1
UniRef50_A0A0J9X2I0	57.455%	275	3.39e-111	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2I0_GEOCN
Q6C8R7_YARLI	52.613%	287	1.36e-100	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D17556g PE=3 SV=1
A0A1E3PP48_9ASCO	53.532%	269	5.99e-101	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50540 PE=3 SV=1
A0A060T685_BLAAD	45.270%	296	3.69e-90	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B09548g PE=3 SV=1
A0A1D8PFD1_CANAL	50.549%	273	2.51e-84	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SRT1 PE=3 SV=1
A0A161HIA6_9ASCO	45.850%	253	7.42e-79	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) OS=Sugiyamaella lignohabitans GN=RER2 PE=3 SV=1
A0A1E4TEJ9_9ASCO	39.689%	257	3.08e-63	Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56760 PE=3 SV=1
SRT1_YEAST	39.262%	298	1.63e-57	Dehydrodolichyl diphosphate synthase complex subunit SRT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRT1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6538

Protein family membership

Decaprenyl diphosphate synthase-like (IPR001441)

Domains and repeats

None predicted.

Detailed signature matches

IPR001441

Decaprenyl diphosphate synthase-like
1. PF01255 (Prenyltransf)
  
  40 - 261
  
  Pfam
  PF01255 (Prenyltransf)
2. SSF64005 (Undecapre...)
  
  30 - 258
  
  SUPERFAMILY
  SSF64005 (Undecaprenyl diphosphate synthase)
3. TIGR00055
  
  33 - 261
  
  TIGRFAMs
  TIGR00055 (TIGR00055)
4. MF_01139 (ISPT)
  
  33 - 265
  
  HAMAP
  MF_01139 (ISPT)
5. cd00475 (Cis_IPPS)
  
  36 - 257
  
  CDD
  cd00475 (Cis_IPPS)
6. G3DSA:3.40.11...
  
  19 - 269
  
  GENE3D
  G3DSA:3.40.1180.10 (G3DSA:3.40.1180.10)
IPR018520

Di-trans-poly-cis-decaprenylcistransferase-like, conserved site
1. PS01066 (UPP_SYNTHASE)
  
  209 - 226
  
  PROSITE patterns
  PS01066 (UPP_SYNTHASE)

no IPR

Unintegrated signatures

NON_CYTOPLASM... (N...)

21 - 343

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 20

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

17 - 20

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

6 - 16

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 5

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)

Residue annotation

active site cd00475

41M

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

42D

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

43G

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

44N

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

45R

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

46R

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

55L

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

59H

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

63F

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

66L

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

85A

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

93R

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

97E

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

104I

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

105I

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

108K

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

160I

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

213R

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

219R

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)

221S

active site
41M, 42D, 43G, 44N, 45R, 46R, 55L, 59H, 63F, 66L, 85A, 93R, 97E, 104I, 105I, 108K, 160I, 213R, 219R, 221S
CDD
cd00475 (Cis_IPPS)
dimer interface cd...

167R

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

168D

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

170I

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

171A

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

174I

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

175R

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

191I

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

192D

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

193I

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

196F

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

207D

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

218T

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

219R

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

220F

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

221S

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

222D

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

225I

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

226W

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

227Q

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

230D

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

231N

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

232C

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

233T

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

234L

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

236F

dimer interface
167R, 168D, 170I, 171A, 174I, 175R, 191I, 192D, 193I, 196F, 207D, 218T, 219R, 220F, 221S, 222D, 225I, 226W, 227Q, 230D, 231N, 232C, 233T, 234L, 236F
CDD
cd00475 (Cis_IPPS)

Protein sequence

>MIA_01453_1
MSLRSWISSFPLMGLITGFSQDILTSIIKTGPIPEHIAFIMDGNRRFAKNNGLELGEGHVAGFESLSTILEVLYSAGVNT
VTVYAFSIENFNRPKHEIDSLFNIIRSKLVLIKDKEQVPARYGIKVRFIGNRDLIPEDIMVLIEELEETTKDMTRGTLNI
AFPYTSRDDIAAAIRQIATSVENGNLDANDIDIVKFEKAMYTGESPDLDIMVRTSGETRFSDFMIWQGCDNCTLEFIDTL
WPAINPWDIFKILFKWSYKSTKYFEKEEIRQSKRADVVKSLSGSRKLNLPNKYMADAFNPTSLPTKVFKGSPSATAGASS
NGKIPPKVSVTEVARNDVLLSKA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_01453_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component