Protein

MIA_01428_1

Length
547 amino acids


Browser: contig02:716661-718305-

Protein function

EGGNOG:0PFR2COX15Cytochrome c oxidase assembly protein
SGD closest match:S000000943COX15Cytochrome c oxidase assembly protein COX15
CGD closest match:CAL0000185068COX15Cox15p

Protein alignments

%idAln lengthE-value
MCA_00365_170.741%5400.0MCA_00365_1
A0A0J9X3V1_GEOCN66.284%5220.0Similar to Saccharomyces cerevisiae YER141W COX15 Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase OS=Geotrichum candidum GN=BN980_GECA02s00923g PE=3 SV=1
A0A060SZ01_BLAAD54.826%5185.97e-170ARAD1C04840p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C04840g PE=3 SV=1
A0A167EGW9_9ASCO64.267%3751.79e-165Cox15p OS=Sugiyamaella lignohabitans GN=COX15 PE=3 SV=1
UniRef50_A0A167EGW964.267%3754.91e-162Cox15p n=9 Tax=Ascomycota TaxID=4890 RepID=A0A167EGW9_9ASCO
Q6C0H5_YARLI55.212%5181.59e-161YALI0F24651p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F24651g PE=3 SV=1
A0A1E3PG88_9ASCO55.804%4481.07e-152COX15-CtaA-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43535 PE=3 SV=1
A0A1E4TAI9_9ASCO60.526%3801.44e-138Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_61886 PE=3 SV=1
A0A1D8PPE8_CANAL53.176%4259.44e-124Cox15p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=COX15 PE=3 SV=1
COX15_YEAST55.959%3861.00e-122Cytochrome c oxidase assembly protein COX15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COX15 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9992
Predicted cleavage: 101

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF02628 (COX15-CtaA)
    1. MF_01665 (HemeA_syn...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_01428_1
MASSLARSQFFFSGNFAITAAAKSCRSQLLVKPCSASKSAAKSLAKNLPFLRANSSSLKADVGFSATSGFAKRQFSTSSS
RTILSTAPFRRQFSTVSQRLASASASNQEMLNAAEQVAKAYTENPLVKTTKRRPVNTWKPVGYWLIFGSGLVFGIVVLGG
LTRLTESGLSITEWKPVTGSVPPRTEQEWQDEFEKYKSSPEFKLLNSNITLPEFKFIFFMEWAHRLWGRAIGLYIVLPAA
YFVFARKVTPHVAGRIGIISALLGLQGFIGWWMVKSGLDNKFLEEPGSHPRVSQYRLATHLCAAFILYSAMLFTGIDIIR
EAQWIKAPEAAVKEITKLDNPAIRRYRSLGKGLFAFVFLTAMSGAFVAGLDAGMIYNSFPYMGETIVPPKAELFNESYNK
QNPESSWALFWRNMLENPTTVQFNHRVLAVSTFCLITAFHLYSHRKRPFLPRSVFRANSAVMGLVSLQVALGISTLIYVV
PTPLAAAHQAGALALLTAVIYMCARLKQPRTAQRLLISALERQASKKAAEKSSKVFVKLPNKASPNA

GO term prediction

Biological Process

GO:0006784 heme a biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane