Protein

MIA_01374_1

Length
355 amino acids

Browser: contig02:535749-536817-

Protein function

EGGNOG:0PHAYNUC1nuclease
SGD closest match:S000003744NUC1Mitochondrial nuclease
CGD closest match:CAL0000174323orf19.967Ribonuclease

Protein alignments

%idAln lengthE-value
MCA_00608_166.852%3595.57e-168MCA_00608_1
A0A1E3PNZ2_9ASCO54.237%3543.12e-120Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49472 PE=4 SV=1
UniRef50_A0A1E3PNZ254.237%3548.47e-117Uncharacterized protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PNZ2_9ASCO
A0A0J9XFA4_GEOCN66.423%2743.63e-127Similar to Saccharomyces cerevisiae YJL208C NUC1 Major mitochondrial nuclease OS=Geotrichum candidum GN=BN980_GECA14s01231g PE=4 SV=1
A0A167FA38_9ASCO64.815%2701.89e-126Nuc1p OS=Sugiyamaella lignohabitans GN=NUC1 PE=4 SV=1
Q5A4X9_CANAL61.484%2831.75e-117Ribonuclease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.967 PE=4 SV=1
NUC1_YEAST60.886%2717.19e-116Mitochondrial nuclease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUC1 PE=1 SV=1
Q6CA82_YARLI60.650%2773.30e-115YALI0D05071p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D05071g PE=4 SV=1
A0A060T622_BLAAD59.298%2851.14e-114ARAD1C10384p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C10384g PE=4 SV=1
A0A1E4TK52_9ASCO56.228%2811.43e-104Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_55788 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0663

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 355

Detailed signature matches

  1. Domain IPR001604
    DNA/RNA non-specific endonuclease
    1. SM00892 (Endonuclea...)
    2. PF01223 (Endonuclea...)
  2. Domain IPR020821
    Extracellular Endonuclease, subunit A
    1. SM00477 (endoplus)
  3. SITE IPR018524
    DNA/RNA non-specific endonuclease, active site
    1. PS01070 (NUCLEASE_N...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.57...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SSF54060 (His-Me fi...)
  8. SignalP-noTM
  9. cd00091 (NUC)

Residue annotation

  1. active site cd00091
  2. substrate binding ...
  3. Mg2+ binding site ...

Protein sequence

>MIA_01374_1
MSFFSPSVATGALFGAGLVSMFWGGGSNSDNVPQVPIGGAPVGSAGSSAFGGLPSKPPPGTTVFSVYDFLQPVSPASGDG
NPGSGLVPINASEFFARYGHPGPSSDLAVRDEFVSFYDRRTRNPHYVVEHITSESLAFRASDGIDRKNSVFKEDPAVPDT
FRSRLRDFFRSGYDRGHLAPAADAKFSQGAMDQTFFLTNMSPQVGDGFNRDYWAHLEDFCRRLTKDYESVRIVTGPLFLP
QRGADGKMRVTYEVIGDGVAVPTHFYKIIVGERPLKTGRPTDIAIGAFVLPNNRIDNKTPLKTFAVPVSAVERASGLEFF
SKLPPNNRKELCQQVKCEIIVRDFSNTVKSLPAPK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

Cellular Component

None predicted.