Protein

MIA_01342_1

Length
763 amino acids

Browser: contig02:421161-423453+

Protein function

EGGNOG:0PGMYFG09790.1DEAD DEAH box helicase
SGD closest match:S000002740IRC3Putative ATP-dependent helicase IRC3
CGD closest match:CAL0000186343orf19.2798Double-stranded DNA-dependent ATPase

Protein alignments

%idAln lengthE-value
MCA_00300_138.603%7595.85e-158MCA_00300_1
A0A0J9XFM4_GEOCN38.601%7156.63e-139Similar to Saccharomyces cerevisiae YDR332W IRC3 Putative RNA helicase of the DEAH/D-box family OS=Geotrichum candidum GN=BN980_GECA14s02705g PE=4 SV=1
UniRef50_A0A0J9XFM438.601%7151.36e-135Similar to Saccharomyces cerevisiae YDR332W IRC3 Putative RNA helicase of the DEAH/D-box family n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XFM4_GEOCN
A0A167CNX5_9ASCO34.375%7362.09e-122Irc3p OS=Sugiyamaella lignohabitans GN=IRC3 PE=4 SV=1
Q6C2M8_YARLI43.848%4473.22e-117YALI0F06534p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F06534g PE=4 SV=1
IRC3_YEAST44.262%4271.22e-109Putative ATP-dependent helicase IRC3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IRC3 PE=1 SV=1
A0A1E4TAH9_9ASCO34.087%6191.58e-111Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_16551 PE=4 SV=1
Q59PU5_CANAL40.835%4317.26e-98Double-stranded DNA-dependent ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2798 PE=4 SV=1
A0A060T456_BLAAD39.356%4043.51e-93ARAD1C38984p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38984g PE=4 SV=1
A0A1E3PRL8_9ASCO31.972%5637.85e-63Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81154 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9948
Predicted cleavage: 45

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 763

Detailed signature matches

  1. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  2. Domain IPR006935
    Helicase/UvrB, N-terminal
    1. PF04851 (ResIII)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00046 (DEXDc)
  4. cd00079 (HELICc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MIA_01342_1
MNMLSCLRQSRACIIRPSIVPIRLRRCSIGQASVRRLTEPSVGFLNVDSSLTQDSHKITLRSYQNECIRECLESFANGKN
RIAVSLATGSGKTVIFSHLLSKVSPQPGQGSTVLILVHRRELATQARDTVKRFCPNLKVQIEMGKESADIDADVIIASVP
TLTAKSLNRLYAPQFDPKRFKLIIVDEAHHAAAPTYLKILRFFGAGTSDTKVYVAGFSATFSRLDGLSLKSAMDHVVYHR
SMMEMIQDGFLSDLRLTTIKASYNLQPLLDEEDAKWEAQERQRLTANTVKGTSPRKIKPPSKRGDYNVHLLSNILNTEEV
NDLVIKVWKRMCLDKYLSTLIFCVDIKHAEDLTAKFQENNISAEYISSKTPDAERAAILARFKNGEVPVLINCAILTEGT
DIPNIDAIMLLRPTRSEALLVQMVGRGLRLHPGKEHCHLIDFVGSTSAQKSGMYTTPTLMGLDPDELVDNASLKDIKEMQ
EQKDREKQELEKQKEKEKKPIHIPPGVNMEKITIETYEGIIDFMNMEPQERELKSKKPKLDIFTSSYAWVSIKDKMYVLT
GKQKQLNLVFESNELDKTGTWRIEKYEVVDKYAYVEHLLNEHGSTKGIKNLRDYEKDSSKKKKYTIKQVVAEGLPTNVAL
KAADSLAESYFESPFMVQRRAPWRNQPASSAQVELLKKMLKKTLESKDIATLHSKFLKLSKEKHEDTDSEPLESIPQDDL
AWLKDITKGEASDILSKAKNGALKDLVKSFYAYLNRLKKQVEI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.