Protein

MIA_01328_1

Length
498 amino acids

Browser: contig02:383178-384725+

Protein function

EGGNOG:0PICPPGUG_01005glutathione synthetase
SGD closest match:S000005409GSH2Glutathione synthetase
CGD closest match:CAL0000176594GSH2Glutathione synthetase

Protein alignments

%idAln lengthE-value
MCA_03118_166.353%5320.0MCA_03118_1
A0A0J9X6W4_GEOCN65.600%5000.0Glutathione synthetase OS=Geotrichum candidum GN=BN980_GECA03s03519g PE=3 SV=1
A0A1E3PEV2_9ASCO57.746%4970.0Glutathione synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84002 PE=3 SV=1
A0A161HN55_9ASCO50.969%5163.07e-164Glutathione synthetase OS=Sugiyamaella lignohabitans GN=GSH2 PE=3 SV=1
UniRef50_A0A161HN5550.969%5168.42e-161Glutathione synthetase n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HN55_9ASCO
A0A060T835_BLAAD49.697%4952.32e-162Glutathione synthetase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D07546g PE=3 SV=1
Q5A359_CANAL51.089%5051.29e-161Glutathione synthetase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GSH2 PE=3 SV=1
Q6CBL1_YARLI50.620%4843.25e-160Glutathione synthetase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C17831g PE=3 SV=1
GSHB_YEAST44.841%5045.33e-127Glutathione synthetase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GSH2 PE=1 SV=1
A0A1E4T9H0_9ASCO42.038%4713.72e-116Glutathione synthetase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_146035 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0250

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 498

Detailed signature matches

  1. Family IPR005615
    Glutathione synthase
    1. TIGR01986
    2. PIRSF001558 (GSHase)
    3. PF03917 (GSH_synth_ATP)
  2. Domain IPR014049
    Glutathione synthase, N-terminal, eukaryotic
    1. G3DSA:3.30.14...
  3. Domain IPR014042
    Glutathione synthase, alpha-helical, eukaryotic
    1. G3DSA:1.10.10...
  4. Domain IPR016185
    Pre-ATP-grasp domain
    1. SSF52440 (PreATP-gr...)
  5. Domain IPR004887
    Glutathione synthase, substrate-binding, eukaryotic
    1. PF03199 (GSH_synthase)
    2. G3DSA:3.40.50...
  6. Domain IPR014709
    Glutathione synthase domain
    1. G3DSA:3.30.14...
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF56059 (Glutathio...)

Protein sequence

>MIA_01328_1
MIYPNYPPETSEKEANFINNTIIDWSLGNGLAMLTPEGQGVTAVHAPVTVYPSPFPKSGFESALNVQTTFNELYAGVSDN
TEWLTEALKDVTVLDHDFTGKLYESYIKAKEIGITQSLSLGIFRSDYIVHNDESETKEDDSVSIKQVEFNTVSVSFGSLS
SKVSQLHTYLSNSDVYGPSAEFLKGKTSISKSIDGLADGLAVAHKEYTKTNALSSENSKQVILFIVQPGERNVFDQRHIE
YSLYNNHGITSYRLTLDNVRSETRLLEVNGVQKLIYIPTNAEVSVIYYRSGYAPTDYPTEEEWEARVYLETSHAIKAPTL
LTQLSGAKKVQQILTDKEIIRKFLPDAASTDLDQLLATFVNLYPMDNSPKGLIARKLAQEQPENFVLKPQREGGGNNVYK
ENIPEFLKHLPEDQWGAYILMEIINPPEFKNKILRAGEVYYGGVISELGVFGTILWDSSNSKILHNEQAGWLLRSKLQSS
NEGGVAAGFGCIDSVYLF

GO term prediction

Biological Process

GO:0006750 glutathione biosynthetic process

Molecular Function

GO:0004363 glutathione synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity

Cellular Component

None predicted.