Protein

MCA_03118_1

Length
530 amino acids

Browser: contigB:3420124-3421764+

RNA-seq: read pairs 3313, FPKM 77.1, percentile rank 74.7% (100% = highest expression)

Protein function

KEGG:K21456GSS glutathione synthase [EC:6.3.2.3]
EGGNOG:0PICPPGUG_01005glutathione synthetase
SGD closest match:S000005409GSH2Glutathione synthetase
CGD closest match:CAL0000176594GSH2Glutathione synthetase

Protein alignments

%idAln lengthE-value
MIA_01328_166.35%5320.0MIA_01328_1
A0A0J9X6W4_GEOCN57.63%5310.0Glutathione synthetase OS=Geotrichum candidum GN=BN980_GECA03s03519g PE=3 SV=1
A0A1E3PEV2_9ASCO55.66%5300.0Glutathione synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84002 PE=3 SV=1
Q5A359_CANAL48.79%5372e-154Glutathione synthetase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GSH2 PE=3 SV=1
Q6CBL1_YARLI48.31%5324e-154Glutathione synthetase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C17831g PE=3 SV=1
UniRef50_Q6CBL148.31%5329e-151Glutathione synthetase n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6CBL1_YARLI
A0A161HN55_9ASCO48.87%5302e-152Glutathione synthetase OS=Sugiyamaella lignohabitans GN=GSH2 PE=3 SV=1
A0A060T835_BLAAD47.15%5264e-149Glutathione synthetase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D07546g PE=3 SV=1
GSHB_YEAST43.80%5328e-120Glutathione synthetase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GSH2 PE=1 SV=1
A0A1E4T9H0_9ASCO41.24%5025e-110Glutathione synthetase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_146035 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0134

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 500 530

Detailed signature matches

  1. Family IPR005615
    Glutathione synthase
    1. TIGR01986
    2. PIRSF001558 (GSHase)
    3. PF03917 (GSH_synth_ATP)
  2. Domain IPR014049
    Glutathione synthase, N-terminal, eukaryotic
    1. G3DSA:3.30.14...
  3. Domain IPR014042
    Glutathione synthase, alpha-helical, eukaryotic
    1. G3DSA:1.10.10...
  4. Domain IPR016185
    Pre-ATP-grasp domain
    1. SSF52440 (PreATP-gr...)
  5. Domain IPR004887
    Glutathione synthase, substrate-binding, eukaryotic
    1. PF03199 (GSH_synthase)
    2. G3DSA:3.40.50...
  6. Domain IPR014709
    Glutathione synthase domain
    1. G3DSA:3.30.14...
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF56059 (Glutathio...)

Protein sequence

>MCA_03118_1
MKYPDYPPKTSESESEKINNTILDWSLGNGLVMLSPHGETGTAKFGSAAVHAPVTVYPSPFPKSGFQHALNVQKNFNLLY
ANISNDVDWLSSALKEKRVIELDDDFTGKLYESYLKAKDAITQPLSLGIFRSDYIVHQDQENQQDKDFSIKQVEFNTVSV
SFGSLSSKVSQLHTYLSESNTYGSSAAFLKDNTRVSKSIDGLADGLAVAHNAYLQQNYPTTFAAKKCIILFIVQPNERNV
FDQRHIEYSLYNKHGGITSHRLTLAQVRDQTELVRSELNGKIVLTLVYKPTRQEVSVVYYRSAYAPTDFPSQKEWDARVY
LETSHAIKCPTLLTQLSGAKKVQQILTDRSVVEKFLLHNQQQHHQQHEHQDHHHHIGNKSSEIDELMQTFVKLYPMDNKS
PEGALAHKLALETPEKYVLKPQREGGGNNIYKDSIPQFLESLPKDKWAAYILMELITPPEYQNKILRNGEIYCGNIVSEL
GIFGSILWNSQTGEILSNEESGWLLRSKLQSSNEGGVAAGFGCIDSVYLF

GO term prediction

Biological Process

GO:0006750 glutathione biosynthetic process

Molecular Function

GO:0004363 glutathione synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity

Cellular Component

None predicted.