Protein

MIA_01325_1

Length
226 amino acids

Browser: contig02:375988-376993+

Protein function

EGGNOG:0PKNHMNSODDestroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SGD closest match:S000001050SOD2Superoxide dismutase [Mn], mitochondrial
CGD closest match:CAL0000191321SOD2Superoxide dismutase

Protein alignments

%idAln lengthE-value
A0A0J9X4J7_GEOCN79.803%2034.78e-126Superoxide dismutase OS=Geotrichum candidum GN=BN980_GECA01s09965g PE=3 SV=1
MCA_00639_182.915%1994.82e-125MCA_00639_1
A0A060SZJ4_BLAAD73.096%1973.14e-110Superoxide dismutase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C01188g PE=3 SV=1
A0A1E3PEV0_9ASCO71.921%2033.13e-110Superoxide dismutase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47707 PE=3 SV=1
Q6CFA1_YARLI68.718%1951.13e-98Superoxide dismutase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08921g PE=3 SV=1
Q5A8Z4_CANAL64.039%2037.25e-95Superoxide dismutase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SOD2 PE=3 SV=1
UniRef50_A0A0F7VDJ565.347%2022.99e-91Superoxide dismutase n=70 Tax=Eukaryota TaxID=2759 RepID=A0A0F7VDJ5_9EURO
A0A1E4TL31_9ASCO64.000%2009.74e-92Superoxide dismutase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22522 PE=3 SV=1
SODM_YEAST62.736%2122.72e-90Superoxide dismutase [Mn], mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SOD2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9991
Predicted cleavage: 29

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 226

Detailed signature matches

  1. Family IPR001189
    Manganese/iron superoxide dismutase
    1. PR01703 (MNSODISMTASE)
    2. PIRSF000349 (MnSOD_...)
  2. Domain IPR019831
    Manganese/iron superoxide dismutase, N-terminal
    1. SSF46609 (Fe,Mn sup...)
    2. PF00081 (Sod_Fe_N)
  3. Domain IPR019832
    Manganese/iron superoxide dismutase, C-terminal
    1. PF02777 (Sod_Fe_C)
    2. SSF54719 (Fe,Mn sup...)
  4. SITE IPR019833
    Manganese/iron superoxide dismutase, binding site
    1. PS00088 (SOD_MN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.28...

Protein sequence

>MIA_01325_1
MTFTLATRNTLRRAASSRAAYTTVFARNKATLPDLEYDFGALEPFISGQINELHYKKHHQTYVNGYNAAIEQLSEAKVKN
DIATQIKLAPAIKFHGGGHLNHSLFWKNLAPVSQGGGVPPAADSPLGKAITEYYGSFDSLVSNVNTKLAGIQGSGWAWIV
KNKETGALDVIAKPNQDIVDGPHIPIVGIDAWEHAYYLQYQNVKVDYFKAIWNVINWKEAEKRFSA

GO term prediction

Biological Process

GO:0006801 superoxide metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004784 superoxide dismutase activity
GO:0046872 metal ion binding

Cellular Component

None predicted.