Protein

MCA_00639_1

Length
227 amino acids

Gene name: SOD2A

Description: Superoxide dismutase [Mn], mitochondrial

Browser: contigA:1993721-1994899+

RNA-seq: read pairs 18048, FPKM 978.1, percentile rank 96.5% (100% = highest expression)

Protein function

Annotation:SOD2ASuperoxide dismutase [Mn], mitochondrial
KEGG:K04564SOD2 superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
EGGNOG:0PKNHMNSODDestroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SGD closest match:S000001050SOD2Superoxide dismutase [Mn], mitochondrial
CGD closest match:CAL0000191321SOD2Superoxide dismutase

Protein alignments

%idAln lengthE-value
A0A0J9X4J7_GEOCN78.85%2088e-125Superoxide dismutase OS=Geotrichum candidum GN=BN980_GECA01s09965g PE=3 SV=1
MIA_01325_175.77%2277e-124MIA_01325_1
A0A060SZJ4_BLAAD72.12%2082e-112Superoxide dismutase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C01188g PE=3 SV=1
A0A1E3PEV0_9ASCO72.22%1981e-105Superoxide dismutase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47707 PE=3 SV=1
Q6CFA1_YARLI71.64%2014e-104Superoxide dismutase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08921g PE=3 SV=1
Q5A8Z4_CANAL67.16%2013e-96Superoxide dismutase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SOD2 PE=3 SV=1
UniRef50_A0A139HDE564.32%1993e-88Uncharacterized protein n=1 Tax=Mycosphaerella eumusae TaxID=321146 RepID=A0A139HDE5_9PEZI
SODM_YEAST62.50%2083e-88Superoxide dismutase [Mn], mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SOD2 PE=1 SV=1
A0A1E4TL31_9ASCO59.41%2029e-86Superoxide dismutase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22522 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9951
Predicted cleavage: 31

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 227

Detailed signature matches

  1. Family IPR001189
    Manganese/iron superoxide dismutase
    1. PR01703 (MNSODISMTASE)
    2. PIRSF000349 (MnSOD_...)
  2. Domain IPR019831
    Manganese/iron superoxide dismutase, N-terminal
    1. SSF46609 (Fe,Mn sup...)
    2. PF00081 (Sod_Fe_N)
  3. Domain IPR019832
    Manganese/iron superoxide dismutase, C-terminal
    1. PF02777 (Sod_Fe_C)
    2. SSF54719 (Fe,Mn sup...)
  4. SITE IPR019833
    Manganese/iron superoxide dismutase, binding site
    1. PS00088 (SOD_MN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.28...

Protein sequence

>MCA_00639_1
MSFTLRTALRRATVARPSVSFSTALGATRGKATLPELDYDFGALEPYISGTINELHYTKHHQTYVNSYNAAIEQLAEAKE
KNDIATQVKLTPAIKFHGGGHVNHSLFWKNLAPKSQGGGEPPSADSALGKAIAQYYGDLDKLIANVNGKLAGIQGSGWAW
IVKNKDTGALDVITTPNQDIVAGSHIPIVGIDAWEHAYYIDYKNVKADYFKAIWNVINWKEAEKRFA

GO term prediction

Biological Process

GO:0006801 superoxide metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004784 superoxide dismutase activity
GO:0046872 metal ion binding

Cellular Component

None predicted.