Protein

MIA_01317_1

Length
433 amino acids


Browser: contig02:352145-353447+

Protein function

EGGNOG:0PFT0ARP4Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity)
SGD closest match:S000001855ACT1Actin
CGD closest match:CAL0000191211ACT1Actin

Protein alignments

%idAln lengthE-value
MCA_00623_161.10%4370.0MCA_00623_1
A0A0J9X4U6_GEOCN54.95%4242e-173Similar to Saccharomyces cerevisiae YJL081C ARP4 Nuclear actin-related protein involved in chromatin remodeling OS=Geotrichum candidum GN=BN980_GECA02s06522g PE=3 SV=1
UniRef50_A0A0J9X4U654.95%4244e-170Similar to Saccharomyces cerevisiae YJL081C ARP4 Nuclear actin-related protein involved in chromatin remodeling n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4U6_GEOCN
A0A167C0M7_9ASCO47.10%4313e-141Actin OS=Sugiyamaella lignohabitans GN=ACT1 PE=3 SV=1
A0A1E3PFP9_9ASCO45.54%4261e-128Actin-related protein 4 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_27372 PE=3 SV=1
Q6C0A9_YARLI43.10%4206e-116YALI0F26345p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26345g PE=3 SV=1
A0A060T6C5_BLAAD40.46%4351e-112ARAD1C18436p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18436g PE=3 SV=1
A0A1E4TII5_9ASCO36.71%4147e-96Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147306 PE=3 SV=1
A0A1D8PFR4_CANAL28.98%4216e-52Actin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ACT1 PE=3 SV=1
ACT_YEAST28.81%4202e-50Actin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ACT1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0103

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. SM00268 (actin_3)
    2. PF00022 (Actin)
    1. PS00432 (ACTINS_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF53067 (Actin-lik...)
  2. cd00012 (NBD_sugar-...)

Residue annotation

  1. nucleotide binding...

Protein sequence

>MIA_01317_1
MTIDSTIISANSQAYKAPHSDEIPAIVIENGSSFTRVGYAGEGLPRHVFTTRYGKDAEGKYYFGDRDVHKFHPGKEIYAP
MADGIVQDWDAMARNWRYSFHELLGVEENATNELPLATTEPTWNPASNKSKAAEIAFEDLGVPLFTLVKNPLCTAYNSEL
PTALIVDIGSSVASVTPILDGNIISNGCLHSRFAGDFLTLHIVNMLNSKNINIVPPYRIKKRVQLDLNQTPDESCYRSDI
DVDKDVTQSYNYFEIDRLLGEFKETTSFVSDVPLQNGTYQSKVARPFELPDGFNTLLTVERLATVEPLFRPSAYPLQGIS
IPEGSLGISELIQQSLIKSEITLETLSVLLNNVIVAGGTTLLQGLAPRINNDLSAVYPNMKIRVLQQNNQLAQKSTVWTG
ASILASLGHYDTTWVSKQEYDELGADIVEKRFK

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.