Protein

MIA_01297_1

Length
307 amino acids


Browser: contig02:274453-275377-

Protein function

EGGNOG:0PJMEFG06084.1methylglutaconyl-CoA hydratase
SGD closest match:S000002443EHD33-hydroxyisobutyryl-CoA hydrolase, mitochondrial
CGD closest match:CAL0000174772EHD33-hydroxyisobutyryl-CoA hydrolase, mitochondrial

Protein alignments

%idAln lengthE-value
MCA_00202_165.517%2901.13e-119MCA_00202_1
A0A0J9XIG7_GEOCN66.421%2712.93e-114Similar to Saccharomyces cerevisiae YDR036C EHD3 3-hydroxyisobutyryl-CoA hydrolase OS=Geotrichum candidum GN=BN980_GECA18s02485g PE=3 SV=1
A0A167FT69_9ASCO62.753%2478.81e-89Ehd3p OS=Sugiyamaella lignohabitans GN=EHD3 PE=3 SV=1
A0A060T3B7_BLAAD61.024%2547.79e-89ARAD1A14366p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A14366g PE=3 SV=1
Q6C0S5_YARLI59.216%2551.02e-86YALI0F22121p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F22121g PE=3 SV=1
UniRef50_Q6C0S559.216%2552.35e-83YALI0F22121p n=6 Tax=Saccharomycetales TaxID=4892 RepID=Q6C0S5_YARLI
A0A1E4TKR5_9ASCO55.422%2491.86e-76Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30513 PE=3 SV=1
A0A1E3PDQ1_9ASCO37.450%2514.00e-31ClpP/crotonase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84168 PE=3 SV=1
HIBCH_YEAST28.571%2173.80e-123-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EHD3 PE=1 SV=2
Q5AI24_CANAL27.429%1756.86e-083-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EHD3 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9992
Predicted cleavage: 23

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 307

Detailed signature matches

    1. PF00378 (ECH_1)
    1. SSF52096 (ClpP/crot...)
    1. PS00166 (ENOYL_COA_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd06558 (crotonase-...)

Residue annotation

  1. substrate binding ...
  2. oxyanion hole (OAH...
  3. trimer interface c...

Protein sequence

>MIA_01297_1
MSTKLLRPLLNNKRAMRSASRIWSGSFYSTSSTDSPIRVQYVSIDTPSFAAAELSDAPPADGSGSIAVVTLNRLKAKNSI
SRQLLDGLHEAVTRDYAGQGARAVIVRSAAPDIFCAGADLKERKTFTPDDTRAFLAKLNHTLDLLESQAVPTIAAIDGVA
LGGGLELALAADFRVLGPAAVVGLPETRLAIIPGAGGTYRLPRLVGTSRALDLVLTGRRVGAAEALQLGVASRALVSAGE
SADEGAWALAREIGAGGPVALVAAKQAVRGAAPAWEAGMYARVVNTEDKFEALAAFAEKRKPVFKGR

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.