Protein
MCA_00202_1
Length
307 amino acids
Gene name: EHD3A
Description: 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
Browser: contigA:630989-631913+
RNA-seq: read pairs 56, FPKM 2.2, percentile rank 12.2% (100% = highest expression)
Protein function
| Annotation: | EHD3A | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | |
|---|---|---|---|
| KEGG: | K05607 | AUH | methylglutaconyl-CoA hydratase [EC:4.2.1.18] |
| EGGNOG: | 0PJME | FG06084.1 | methylglutaconyl-CoA hydratase |
| SGD closest match: | S000002443 | EHD3 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial |
| CGD closest match: | CAL0000174772 | EHD3 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XIG7_GEOCN | 71.97% | 289 | 5e-138 | Similar to Saccharomyces cerevisiae YDR036C EHD3 3-hydroxyisobutyryl-CoA hydrolase OS=Geotrichum candidum GN=BN980_GECA18s02485g PE=3 SV=1 |
| MIA_01297_1 | 65.52% | 290 | 8e-122 | MIA_01297_1 |
| A0A060T3B7_BLAAD | 64.52% | 248 | 5e-90 | ARAD1A14366p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A14366g PE=3 SV=1 |
| Q6C0S5_YARLI | 60.39% | 255 | 4e-89 | YALI0F22121p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F22121g PE=3 SV=1 |
| UniRef50_Q6C0S5 | 60.39% | 255 | 9e-86 | YALI0F22121p n=6 Tax=Saccharomycetales TaxID=4892 RepID=Q6C0S5_YARLI |
| A0A167FT69_9ASCO | 59.93% | 272 | 4e-88 | Ehd3p OS=Sugiyamaella lignohabitans GN=EHD3 PE=3 SV=1 |
| A0A1E4TKR5_9ASCO | 52.21% | 249 | 2e-75 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30513 PE=3 SV=1 |
| A0A1E3PDQ1_9ASCO | 35.46% | 251 | 1e-28 | ClpP/crotonase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84168 PE=3 SV=1 |
| HIBCH_YEAST | 29.79% | 188 | 2e-12 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EHD3 PE=1 SV=2 |
| Q5AI24_CANAL | 28.74% | 174 | 2e-08 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EHD3 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9700
Protein family membership
- Crotonase superfamily (IPR001753)
Domains and repeats
-
Domain
-
Domain
1
50
100
150
200
250
307
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd06558 (crotonase-...)
Residue annotation
-
substrate binding ...
-
oxyanion hole (OAH...
-
trimer interface c...
Protein sequence
>MCA_00202_1 MLKTITPRTAMLAVKPLCRPTLAPTVTRIVLSNNYSTIKESDPIKINYLPLDAAEFKSATFSDTPNGANIAVVTLDRPKA KNSISLQLLDQLFEAAHKDYISQETRALIIRSSTPDIFCAGADLKERKTFTALDTRNFLKKLNYTMDLFENQPIPTISAI SGVALGGGLELALSTDFRVLGAKASVGLTESRLAIIPGAGGTFRLPRLIGQSKALDLILTGRRVGSKEALDLGIATRAVE DADEGALALARDIASGGPLAIIAGKKAVRGASPEWEAAMYERVVNSEDKFEALAAFAEKRKPIFKGR
GO term prediction
Biological Process
GO:0008152 metabolic process
Molecular Function
GO:0003824 catalytic activity
Cellular Component
None predicted.