Protein
MIA_01291_1
Length
554 amino acids
Browser: contig02:261028-262693+
Protein function
| EGGNOG: | 0PHKA | HEM1 | 5-aminolevulinate synthase |
|---|---|---|---|
| SGD closest match: | S000002640 | HEM1 | 5-aminolevulinate synthase, mitochondrial |
| CGD closest match: | CAL0000189686 | HEM1 | 5-aminolevulinate synthase, mitochondrial |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_00212_1 | 76.064% | 564 | 0.0 | MCA_00212_1 |
| A0A0J9XHV1_GEOCN | 69.649% | 570 | 0.0 | 5-aminolevulinate synthase OS=Geotrichum candidum GN=BN980_GECA19s00626g PE=3 SV=1 |
| A0A167DL55_9ASCO | 59.864% | 588 | 0.0 | 5-aminolevulinate synthase OS=Sugiyamaella lignohabitans GN=HEM1 PE=3 SV=1 |
| A0A060TF42_BLAAD | 62.612% | 559 | 0.0 | 5-aminolevulinate synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D20020g PE=3 SV=1 |
| HEM1_YARLI | 59.792% | 577 | 0.0 | 5-aminolevulinate synthase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HEM1 PE=3 SV=1 |
| UniRef50_Q6CCW0 | 59.792% | 577 | 0.0 | 5-aminolevulinate synthase, mitochondrial n=37 Tax=Fungi TaxID=4751 RepID=HEM1_YARLI |
| HEM1_CANAL | 59.132% | 553 | 0.0 | 5-aminolevulinate synthase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HEM1 PE=3 SV=2 |
| A0A1E3PS32_9ASCO | 56.771% | 576 | 0.0 | 5-aminolevulinate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81251 PE=3 SV=1 |
| A0A1E4TMF0_9ASCO | 56.172% | 559 | 0.0 | 5-aminolevulinate synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_95462 PE=3 SV=1 |
| HEM1_YEAST | 64.348% | 460 | 0.0 | 5-aminolevulinate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HEM1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.6839
Predicted cleavage: 39
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
554
Detailed signature matches
no IPR
Unintegrated signatures
-
cd06454 (KBL_like)
Residue annotation
-
substrate-cofactor...
-
pyridoxal 5'-phosp...
-
catalytic residue ...
Protein sequence
>MIA_01291_1 MESLARQSKALCPFLHKTSTSTLKRLSSQAAIASVARGCPIMGHAMEIQESKAPHSRSFSTVREVEISKEFIEIPVTKKA AAPNKAGAAPAFDDKQASFNYEKLYESDLQRKHQDKSYRYFNNINRLANKFPHAHRATESDEVTVWCANDYLGMGSHPVV TQAMHSTIDKYGAGAGGTRNIAGHNKHALQLEASLADLHRKDAALVFTSCFVANDATLALLGKKFPNCVYFSDEMNHASM IEGIRHSGAEKVIWKHNDLADLEAKLAKYPKSQPKIIAFESVYSMSGNIAPIEAICDLADKYGALTFLDEVHAVGMYGPR GAGVAEHLDFEYHDSNCNPETLVSTNPDGSARRDVMSRVDMITGTLGKAFGCMGGYVAGSKHFIDWVRSYAPGFIFTTSL PPAVMAGANAAINYQKTSLKERILQQAHTAYVKRELGERGIPVVPNPSHIVPVLVGNAEKAKEASDMLLEKYGIYVQAIN YPTVPIGHERLRITPTPGHNKELSDHLIKALDETFTTLGLDRIKDWEAKGGRCGVAEPGYDHIKPIWTPKQLKQ
GO term prediction
Biological Process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0033014 tetrapyrrole biosynthetic process
Molecular Function
GO:0003824 catalytic activity
GO:0003870 5-aminolevulinate synthase activity
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
Cellular Component
None predicted.