Protein

MIA_01286_1

Length
339 amino acids

Browser: contig02:253272-254292+

Protein function

EGGNOG:0PG3GPGUG_03601Uridylate kinase
SGD closest match:S000001507URA6Uridylate kinase
CGD closest match:CAL0000189392URA6Uridylate kinase

Protein alignments

%idAln lengthE-value
MCA_00218_178.030%2642.28e-159MCA_00218_1
A0A0J9X8A0_GEOCN68.512%2891.07e-141Uridylate kinase OS=Geotrichum candidum GN=URA6 PE=3 SV=1
A0A060T679_BLAAD60.145%2769.77e-115Uridylate kinase OS=Blastobotrys adeninivorans GN=URA6 PE=3 SV=1
A0A1E3PGZ3_9ASCO55.063%3162.40e-113Uridylate kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=URA6 PE=3 SV=1
A0A167CX39_9ASCO58.484%2773.67e-111Uridylate kinase OS=Sugiyamaella lignohabitans GN=URA6 PE=3 SV=1
UniRef50_A0A167CX3958.484%2771.01e-107Uridylate kinase n=32 Tax=Fungi TaxID=4751 RepID=A0A167CX39_9ASCO
Q59KZ3_CANAL51.342%2981.55e-95Uridylate kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=URA6 PE=3 SV=1
KCY_YEAST64.251%2075.36e-95Uridylate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=URA6 PE=1 SV=1
Q6C2B0_YARLI63.810%2102.74e-93Uridylate kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=URA6 PE=3 SV=1
A0A1E4TD72_9ASCO64.216%2046.83e-90Uridylate kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=URA6 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9953
Predicted cleavage: 78

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 339

Detailed signature matches

  1. Family IPR000850
    Adenylate kinase/UMP-CMP kinase
    1. PR00094 (ADENYLTKNASE)
    2. MF_00235 (Adenylate...)
    3. cd01428 (ADK)
  2. Family IPR006266
    UMP-CMP kinase
    1. MF_03172 (Adenylate...)
    2. TIGR01359
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. SITE IPR033690
    Adenylate kinase, conserved site
    1. PS00113 (ADENYLATE_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. PF00406 (ADK)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. SignalP-noTM
  10. TRANSMEMBRANE (Tran...)

Residue annotation

  1. AMP-binding site c...
  2. ATP-AMP (Ap5A)-bin...

Protein sequence

>MIA_01286_1
MLSRTSLRLLFLTGRASASAAAPALARAANFTTIAKAARPLASKNLASVWTTPSAKTTILRASQRAYSVQTTPTPRDDGP
KFRYIVLLVILGTAGFVWAEKKVRKKKPRDFNEEDYEAIKKRARIMHKKTAFTSEEALVIFVLGGPGSGKGTQCANLVRD
YDFVHLSAGDLLRAEQAREGSQYGELISNYIKEGKIVPQEVTIALLRNAMRDAIVKRLDEDPNATIEQGPVRFLIDGFPR
KMDQALKFEDDVCISRFTLFFECPEEVMLKRLLKRGETSGRSDDNVESIKKRFHTFVDTSMPVIEYFDKAGKVFRVSCDQ
PVEDVYTQVRGVLQDRLGI

GO term prediction

Biological Process

GO:0006139 nucleobase-containing compound metabolic process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221 pyrimidine nucleotide biosynthetic process

Molecular Function

GO:0004127 cytidylate kinase activity
GO:0005524 ATP binding
GO:0009041 uridylate kinase activity
GO:0019205 nucleobase-containing compound kinase activity

Cellular Component

None predicted.