Protein

MIA_01281_1

Length
469 amino acids

Browser: contig02:241815-243225+

Protein function

EGGNOG:0PGMGPGUG_01006bleomycin hydrolase
SGD closest match:S000005183LAP3Cysteine proteinase 1, mitochondrial
CGD closest match:CAL0000187653LAP3Bleomycin hydrolase

Protein alignments

%idAln lengthE-value
MCA_00223_172.059%4760.0MCA_00223_1
A0A0J9X6B9_GEOCN63.758%4470.0Similar to Saccharomyces cerevisiae YNL239W LAP3 Cysteine aminopeptidase with homocysteine-thiolactonase activity OS=Geotrichum candidum GN=BN980_GECA03s07083g PE=4 SV=1
UniRef50_A0A0J9XHA160.738%4610.0Similar to Saccharomyces cerevisiae YNL239W LAP3 Cysteine aminopeptidase with homocysteine-thiolactonase activity n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHA1_GEOCN
A0A060TIF4_BLAAD56.347%4490.0ARAD1D46112p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D46112g PE=4 SV=1
BLH1_YEAST45.778%4508.55e-152Cysteine proteinase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAP3 PE=1 SV=3
A0A1E4TGU8_9ASCO46.288%4584.06e-142Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_115187 PE=4 SV=1
Q5A6L5_CANAL45.652%4608.03e-142Bleomycin hydrolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LAP3 PE=4 SV=1
A0A167FWM4_9ASCO45.354%4524.49e-138Lap3p OS=Sugiyamaella lignohabitans GN=LAP3 PE=4 SV=1
Q6C1A4_YARLI43.590%4682.76e-128YALI0F17974p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F17974g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0117

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

  1. Family IPR004134
    Peptidase C1B, bleomycin hydrolase
    1. PF03051 (Peptidase_...)
    2. PIRSF005700 (PepC)
    3. cd00585 (Peptidase_C1B)
  2. SITE IPR000169
    Cysteine peptidase, cysteine active site
    1. PS00139 (THIOL_PROT...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.90.70.10
  2. SSF54001 (Cysteine ...)

Residue annotation

  1. trimer interface c...
  2. active site cd00585
  3. G bulge cd00585

Protein sequence

>MIA_01281_1
MSSSAPEKKDSATPASYPLQPTQLGAWSTDLKADVVTALASTVIVNHGAATALINRDARSRGLINVYSDAVTPEGAPTMN
QKQSGRCWLFAGTNQLRIGIMRRLNLAELELSPSYLFFYDKLEKANFFLEQIEQTAASEEVESRLVQHLLSDPVIDGGQY
DMFANIVAKYGLVPNSVYGDSFNTLASRNMNYVITTLLRQYAQEIREAIAGGADAAQLRAQREAQMGQIFKLLSVFLGTP
PGPTDEILWEYVDKDKKYHSVKTTPLGFYKDVVQYDVADTVSLLNDPRNEYNRLITVDRLGNVAGRPYVTYVNAEIDVLA
RTAVALIKANEPVFFGTHTPIYHDRKSGIIDTALWDYKLVGFDPKQNKADRLRFHQSLMTHAMLLTAVHVDPESGEPVRW
KVENSWGTEPGIKGYFIMSHEFFKEYVYQIVAPKRAIEDEGVKAVVEDWDNQKPIILPPWDPCGALAKL

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004197 cysteine-type endopeptidase activity

Cellular Component

None predicted.