Protein

MIA_01278_1

Length
572 amino acids

Browser: contig02:234096-235874+

Protein function

EGGNOG:0PGFRPUS1tRNA pseudouridine synthase
SGD closest match:S000006133PUS1tRNA pseudouridine synthase 1
CGD closest match:CAL0000183350PUS1tRNA pseudouridine synthase 1

Protein alignments

%idAln lengthE-value
A0A0J9XET1_GEOCN58.226%5410.0Similar to Saccharomyces cerevisiae YPL212C PUS1 tRNA:pseudouridine synthase OS=Geotrichum candidum GN=BN980_GECA13s02089g PE=4 SV=1
UniRef50_A0A0J9XET158.226%5410.0Similar to Saccharomyces cerevisiae YPL212C PUS1 tRNA:pseudouridine synthase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XET1_GEOCN
A0A060TGU0_BLAAD60.317%4410.0tRNA pseudouridine synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D33506g PE=3 SV=1
A0A167DBI4_9ASCO54.860%4632.47e-170tRNA pseudouridine synthase OS=Sugiyamaella lignohabitans GN=PUS1 PE=3 SV=1
PUS1_YARLI53.780%4632.45e-165tRNA pseudouridine synthase 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PUS1 PE=3 SV=1
MCA_00230_174.046%2624.24e-127MCA_00230_1
A0A1E3PPH6_9ASCO65.327%1992.59e-90Pseudouridine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45384 PE=4 SV=1
PUS1_YEAST67.213%1838.74e-79tRNA pseudouridine synthase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PUS1 PE=1 SV=1
PUS1_CANAL62.176%1932.53e-75tRNA pseudouridine synthase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PUS1 PE=3 SV=2
A0A1E4TK33_9ASCO53.266%1993.68e-68tRNA pseudouridine synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30361 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0235

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 572

Detailed signature matches

  1. Domain IPR020103
    Pseudouridine synthase, catalytic domain
    1. SSF55120 (Pseudouri...)
  2. Domain IPR020097
    Pseudouridine synthase I, TruA, alpha/beta domain
    1. PF01416 (PseudoU_sy...)
  3. Domain IPR020095
    Pseudouridine synthase I, TruA, C-terminal
    1. G3DSA:3.30.70...
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.70...
  3. cd02568 (PseudoU_sy...)
  4. mobidb-lite (disord...)

Residue annotation

  1. probable active si...

Protein sequence

>MIA_01278_1
MAGDDNIRKRKDKWGRPRTSNRRDDKRQRKDDKKEGEGKESRVWGPREDNGEPREPRKPKRKVAVMIGYCGTGYCGMQIN
PPNKTIEEDLYKAFVEAGAISKDNANDLKKSGFMRAARTDKGVHAAGNVVSLKLIIEDPDIVEKINAHLPDQIRVWGISR
TNKAFECRKMCSSRIYEYLIPSYSFLPPKPESALAERLEIANKKYPGAKRPDPEGEKFWSDIKKKLLGEGIVESDIKKAQ
KIAEDKEQEELQKAQQKILDARAKSEGKKDSAEATANAEKKAEEEAEDKIEETAEEKTEDNAETPEENASKLKFSEMVKK
IKTAEHEARRAYRISPDRLELIREVLKQYEGVHNFHNFTISKTFKDPSAQRNMKSLTVSEGKIIENTEWLSIKIHGQSFM
MHQIRKMIAMTALIVRCGTPVSHLKEAFGPADLNIPKAPGLGLLLEQPVYDAYNLRLGTFGYDPLNFEKWKDEVEAFKFK
HIYDKIYSEEEREHVFHKFFSFIDSFRGDSTFGYLAVGPKDVGAEEEKSSNGIAAGVATGVAAGAAAVVASKFVMAGDDE
DDEIPADADTEG

GO term prediction

Biological Process

GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification

Molecular Function

GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity

Cellular Component

None predicted.