MIA_01271_1

Protein

Length

1,441 amino acids

Protein function

EGGNOG:	0PFG9	FG02482.1	Sulfite reductase
SGD closest match:	S000003898	MET5	Sulfite reductase [NADPH] subunit beta
CGD closest match:	CAL0000177258	ECM17	Sulfite reductase (NADPH) subunit beta

Protein alignments

	%id	Aln length
MCA_05476_1	73.256%	1462	MCA_05476_1
A0A0J9X893_GEOCN	70.081%	1484	Similar to Saccharomyces cerevisiae YJR137C MET5 Sulfite reductase beta subunit OS=Geotrichum candidum GN=BN980_GECA05s01275g PE=4 SV=1
A0A167CR93_9ASCO	63.932%	1475	Sulfite reductase (NADPH) subunit beta OS=Sugiyamaella lignohabitans GN=MET5 PE=4 SV=1
A0A060TAI8_BLAAD	61.081%	1480	ARAD1D27368p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27368g PE=4 SV=1
A0A1E3PM84_9ASCO	61.859%	1463	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82332 PE=4 SV=1
Q6C9H5_YARLI	58.783%	1446	YALI0D11176p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D11176g PE=4 SV=1
A0A1D8PHL8_CANAL	55.220%	1456	Sulfite reductase (NADPH) subunit beta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ECM17 PE=4 SV=1
UniRef50_D5GL57	58.861%	1247	Uncharacterized protein n=265 Tax=Fungi TaxID=4751 RepID=D5GL57_TUBMM
MET5_YEAST	51.692%	1389	Sulfite reductase [NADPH] subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET5 PE=1 SV=1
A0A1E4TMH3_9ASCO	49.336%	1431	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56491 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1341

Protein family membership

Flavodoxin-like (IPR001094)

Domains and repeats

Domain
195 - 358
Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (IPR009014)
683 - 849
Flavoprotein-like domain (IPR029039)
Flavodoxin/nitric oxide synthase (IPR008254)
852 - 984
Nitrite/Sulfite reductase ferredoxin-like domain (IPR005117)
1,209 - 1,289
Nitrite/Sulfite reductase ferredoxin-like domain (IPR005117)
Domain
353 - 718
Thiamin diphosphate-binding fold (IPR029061)
1,011 - 1,191
Nitrite/sulphite reductase 4Fe-4S domain (IPR006067)
1,342 - 1,424
Nitrite/sulphite reductase 4Fe-4S domain (IPR006067)

1 200 400 600 800 1000 1200 1441

Detailed signature matches

IPR001094

Flavodoxin-like
1. PR00369 (FLAVODOXIN)
  
  768 - 778
  
  PRINTS
  PR00369 (FLAVODOXIN)
  
  688 - 701
  
  PRINTS
  PR00369 (FLAVODOXIN)
  
  736 - 747
  
  PRINTS
  PR00369 (FLAVODOXIN)
  
  799 - 818
  
  PRINTS
  PR00369 (FLAVODOXIN)
IPR009014

Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
1. G3DSA:3.40.50...
  
  195 - 358
  
  GENE3D
  G3DSA:3.40.50.920 (G3DSA:3.40.50.920)
2. SSF52922 (TK C-term...)
  
  195 - 340
  
  SUPERFAMILY
  SSF52922 (TK C-terminal domain-like)
IPR029061

Thiamin diphosphate-binding fold
1. SSF52518 (Thiamin d...)
  
  353 - 718
  
  SUPERFAMILY
  SSF52518 (Thiamin diphosphate-binding fold (THDP-binding))
IPR029039

Flavoprotein-like domain
1. SSF52218 (Flavoprot...)
  
  684 - 840
  
  SUPERFAMILY
  SSF52218 (Flavoproteins)
2. G3DSA:3.40.50...
  
  683 - 849
  
  GENE3D
  G3DSA:3.40.50.360 (G3DSA:3.40.50.360)
IPR008254

Flavodoxin/nitric oxide synthase
1. PS50902 (FLAVODOXIN...)
  
  687 - 836
  
  PROSITE profiles
  PS50902 (FLAVODOXIN_LIKE)
2. PF00258 (Flavodoxin_1)
  
  689 - 831
  
  Pfam
  PF00258 (Flavodoxin_1)
IPR005117

Nitrite/Sulfite reductase ferredoxin-like domain
1. PF03460 (NIR_SIR_ferr)
  
  1,215 - 1,283
  
  Pfam
  PF03460 (NIR_SIR_ferr)
  
  916 - 973
  
  Pfam
  PF03460 (NIR_SIR_ferr)
2. SSF55124 (Nitrite/S...)
  
  1,209 - 1,289
  
  SUPERFAMILY
  SSF55124 (Nitrite/Sulfite reductase N-terminal domain-like)
  
  852 - 984
  
  SUPERFAMILY
  SSF55124 (Nitrite/Sulfite reductase N-terminal domain-like)
IPR006067

Nitrite/sulphite reductase 4Fe-4S domain
1. PF01077 (NIR_SIR)
  
  1,011 - 1,191
  
  Pfam
  PF01077 (NIR_SIR)
  
  1,342 - 1,424
  
  Pfam
  PF01077 (NIR_SIR)
IPR006066

Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site
1. PR00397 (SIROHAEM)
  
  1,344 - 1,362
  
  PRINTS
  PR00397 (SIROHAEM)
  
  1,296 - 1,314
  
  PRINTS
  PR00397 (SIROHAEM)

no IPR

Unintegrated signatures

Coil

1,438 - 1,441

COILS
Coil (Coil)
G3DSA:3.30.41...

1,295 - 1,432

GENE3D
G3DSA:3.30.413.10 (G3DSA:3.30.413.10)

978 - 1,210

GENE3D
G3DSA:3.30.413.10 (G3DSA:3.30.413.10)

916 - 977

GENE3D
G3DSA:3.30.413.10 (G3DSA:3.30.413.10)
G3DSA:3.40.50...

382 - 677

GENE3D
G3DSA:3.40.50.970 (G3DSA:3.40.50.970)
SSF56014 (Nitrite a...)

1,293 - 1,425

SUPERFAMILY
SSF56014 (Nitrite and sulphite reductase 4Fe-4S domain-like)

1,064 - 1,207

SUPERFAMILY
SSF56014 (Nitrite and sulphite reductase 4Fe-4S domain-like)

985 - 1,036

SUPERFAMILY
SSF56014 (Nitrite and sulphite reductase 4Fe-4S domain-like)

Protein sequence

>MIA_01271_1
MVLKSSYESVAYIAQNAADKVFAFQPALSVSSDFSKHFDKPTTIRNGNDGFAQILEYAIANPASIIAVSVSLNELFNAIT
LLPKLAGSSIVIHIDTSSPSSTPDYGKIAALRHLGFAFLQSFGAADSQSVAFASYIVAKSAAQPVFHFFYPTDSAPTSPI
SAQSIRDALTSFGAAETSVSLSEAVEEALKYTIVKPFEYIGPKNPTTAIVLFASSVEPFLQAISQASSSDSYKSIGIVLI
HAYRPWSSANLLSVLPASVKKLALVEQLSRRITAWSPLVQDFVSDLTNDTLTTTPPQIVPFQLGVITLDNVRSALKAIAA
NLGSDSPVNNLFIGSKPEATSSVETSPEAQKAAKTLESAYTKVLHQIFNDQIDILNSTDKPTTGFENTPEYGYGAFLATS
EKKTELAYQAEEAVKSNDFASGSKSNLVKHLSSWVLESRSFTSVQKSKNANEQTKKLLDLLHASASSKTANDLLKNENLF
PLKSSWIVGSDAWSYDLGNSGVHHVISSGKNLNLLIIDSQPYSEVVANTSSLRKKDVGLYSMNFGNVYVASVAVYSSYTQ
LLQALLEAEAFDGPSVVLAYLPYSAETDSPVTVLQETKRAVDSGYWPLYRYNPTLETDSFKLDSSRIKKNLKDFLDRENH
LTLLSQRNPTFAKTLSESYGTEVRNQQKHRAKAALHSLLEGLSGPPLTVLFASDGGNAENLAKKLARRAKGRGVKSVVLA
MDDYPVEDLPSEENLILITSTAGQGELPQNGRNFWEAIKSSTDLDLATVKYSVFGLGDSQYWPRKQDKHYYNKPSKDLFN
KLQLLGASELVPLGQGDDQDPDGYQQGYNAWEPLVWTALGVDNVAAADEPPPITNEDMKAGSDFLRGTIAEALQDESTGA
ISAVDQQLTKFHGIYMQDDRDIRDERKSAGLEPAYSFMVRVRLPGCVSTPEQWLKMDELADAYGNHTLKITTRGTFQLHG
VIKKLLKPAIRGMNSALLDTVAACGDVDRNVVAAALPNNKKIHDEIVKYSYLISEHLLPQTTAYYEIWLEGADDLDQPGY
TETFQNRPDGPKKKKVLISESTLVDQEPLYGPLYLPRKFKINIAVPPYNDVDVFAHDIGLIAIVEDNELVGFNVYAGGGM
GTTHNNKKTYPRMGSIQGFVTKDKIIDACEKIMLVQRDHGDRKNRKHARLKYTIDDMGNDVFRSKVEERLGYTFEQERPY
HFESNTDQFGWITDETGMHHFTTFVENGRVEDTPELQFKTGFRELATLMKGTGAEFRLTANQHILVSNVSDELLPSVKEV
MAKYKLDNTAFSGLRLSSAACVAFPTCGLAMAESERYLPVLITKLEEALEEYGLRHDSIVMRMTGCPNGCARPWMAEIAC
VGKAFGAYNLMLGGGHRGERINKLYRSSLKEDEILAELKPMFKRWSLERNEGEPFGDWVIRAGIIAATREGKDFWENVAE
E

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0051536 iron-sulfur cluster binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features