MCA_05476_1

Protein

Length

1,462 amino acids

Browser: contigD:1415627-1420144-

RNA-seq: read pairs 10991, FPKM 92.8, percentile rank 77.4% (100% = highest expression)

Protein function

KEGG:	K00381	cysI	sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2]
EGGNOG:	0PFG9	FG02482.1	Sulfite reductase
SGD closest match:	S000003898	MET5	Sulfite reductase [NADPH] subunit beta
CGD closest match:	CAL0000177258	ECM17	Sulfite reductase (NADPH) subunit beta

Protein alignments

	%id	Aln length
MIA_01271_1	72.82%	1442	MIA_01271_1
A0A0J9X893_GEOCN	68.07%	1472	Similar to Saccharomyces cerevisiae YJR137C MET5 Sulfite reductase beta subunit OS=Geotrichum candidum GN=BN980_GECA05s01275g PE=4 SV=1
A0A167CR93_9ASCO	63.88%	1437	Sulfite reductase (NADPH) subunit beta OS=Sugiyamaella lignohabitans GN=MET5 PE=4 SV=1
A0A060TAI8_BLAAD	63.10%	1401	ARAD1D27368p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27368g PE=4 SV=1
A0A1E3PM84_9ASCO	61.05%	1435	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82332 PE=4 SV=1
Q6C9H5_YARLI	59.35%	1444	YALI0D11176p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D11176g PE=4 SV=1
A0A1D8PHL8_CANAL	55.77%	1386	Sulfite reductase (NADPH) subunit beta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ECM17 PE=4 SV=1
UniRef50_D5GL57	58.35%	1258	Uncharacterized protein n=265 Tax=Fungi TaxID=4751 RepID=D5GL57_TUBMM
MET5_YEAST	51.79%	1425	Sulfite reductase [NADPH] subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET5 PE=1 SV=1
A0A1E4TMH3_9ASCO	48.27%	1446	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56491 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5473

Protein family membership

Flavodoxin-like (IPR001094)

Domains and repeats

Domain
211 - 372
Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (IPR009014)
702 - 863
Flavoprotein-like domain (IPR029039)
Flavodoxin/nitric oxide synthase (IPR008254)
871 - 1,004
Nitrite/Sulfite reductase ferredoxin-like domain (IPR005117)
1,229 - 1,309
Nitrite/Sulfite reductase ferredoxin-like domain (IPR005117)
Domain
369 - 737
Thiamin diphosphate-binding fold (IPR029061)
1,030 - 1,213
Nitrite/sulphite reductase 4Fe-4S domain (IPR006067)
1,361 - 1,444
Nitrite/sulphite reductase 4Fe-4S domain (IPR006067)

1 200 400 600 800 1000 1200 1462

Detailed signature matches

IPR001094

Flavodoxin-like
1. PR00369 (FLAVODOXIN)
  
  755 - 766
  
  PRINTS
  PR00369 (FLAVODOXIN)
  
  788 - 798
  
  PRINTS
  PR00369 (FLAVODOXIN)
  
  707 - 720
  
  PRINTS
  PR00369 (FLAVODOXIN)
  
  819 - 838
  
  PRINTS
  PR00369 (FLAVODOXIN)
IPR009014

Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
1. G3DSA:3.40.50...
  
  211 - 372
  
  GENE3D
  G3DSA:3.40.50.920 (G3DSA:3.40.50.920)
2. SSF52922 (TK C-term...)
  
  212 - 363
  
  SUPERFAMILY
  SSF52922 (TK C-terminal domain-like)
IPR029061

Thiamin diphosphate-binding fold
1. SSF52518 (Thiamin d...)
  
  369 - 737
  
  SUPERFAMILY
  SSF52518 (Thiamin diphosphate-binding fold (THDP-binding))
IPR029039

Flavoprotein-like domain
1. SSF52218 (Flavoprot...)
  
  703 - 860
  
  SUPERFAMILY
  SSF52218 (Flavoproteins)
2. G3DSA:3.40.50...
  
  702 - 863
  
  GENE3D
  G3DSA:3.40.50.360 (G3DSA:3.40.50.360)
IPR008254

Flavodoxin/nitric oxide synthase
1. PS50902 (FLAVODOXIN...)
  
  706 - 856
  
  PROSITE profiles
  PS50902 (FLAVODOXIN_LIKE)
2. PF00258 (Flavodoxin_1)
  
  708 - 851
  
  Pfam
  PF00258 (Flavodoxin_1)
IPR005117

Nitrite/Sulfite reductase ferredoxin-like domain
1. PF03460 (NIR_SIR_ferr)
  
  1,236 - 1,303
  
  Pfam
  PF03460 (NIR_SIR_ferr)
  
  936 - 994
  
  Pfam
  PF03460 (NIR_SIR_ferr)
2. SSF55124 (Nitrite/S...)
  
  1,229 - 1,309
  
  SUPERFAMILY
  SSF55124 (Nitrite/Sulfite reductase N-terminal domain-like)
  
  871 - 1,004
  
  SUPERFAMILY
  SSF55124 (Nitrite/Sulfite reductase N-terminal domain-like)
IPR006067

Nitrite/sulphite reductase 4Fe-4S domain
1. PF01077 (NIR_SIR)
  
  1,030 - 1,213
  
  Pfam
  PF01077 (NIR_SIR)
  
  1,361 - 1,444
  
  Pfam
  PF01077 (NIR_SIR)
IPR006066

Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site
1. PR00397 (SIROHAEM)
  
  1,364 - 1,382
  
  PRINTS
  PR00397 (SIROHAEM)
  
  1,316 - 1,334
  
  PRINTS
  PR00397 (SIROHAEM)

no IPR

Unintegrated signatures

Coil

415 - 435

COILS
Coil (Coil)
G3DSA:3.30.41...

1,315 - 1,452

GENE3D
G3DSA:3.30.413.10 (G3DSA:3.30.413.10)

998 - 1,230

GENE3D
G3DSA:3.30.413.10 (G3DSA:3.30.413.10)
G3DSA:3.40.50...

398 - 696

GENE3D
G3DSA:3.40.50.970 (G3DSA:3.40.50.970)
SSF56014 (Nitrite a...)

1,313 - 1,446

SUPERFAMILY
SSF56014 (Nitrite and sulphite reductase 4Fe-4S domain-like)

1,084 - 1,227

SUPERFAMILY
SSF56014 (Nitrite and sulphite reductase 4Fe-4S domain-like)

1,005 - 1,056

SUPERFAMILY
SSF56014 (Nitrite and sulphite reductase 4Fe-4S domain-like)

Protein sequence

>MCA_05476_1
MVKQLSSSLESVAHVSSVLAKPFVFQPSLSSKLPSSLDSSNSVVIRNGTDGLAQVIAALKVSQDQLSVIISLNELFNGII
HLQNLSNHKIVFHIDTSSISKSLPDYGKIAALRHLGFTFLQSFGTADSQKIALASYLISKRQSQPVFHFFYPSSSASANE
ISPDSLLSSYESTESIISLSESIEEHGEKQEPITESLTQTISDVFTSLSLNSFEYIGPKNATSAVVLFGSSYDLFIQAIN
GASKSDIYSQVGLVLIHVYRPWSSKQLLSVLPKSVTRLGLVEQLKKKITTWSPLIQDFIADASDEKLFNSIETTISFQLG
GVTSENVITVLKAISLNLTSSNPVNNLFVGSREQQPQQTFEVSESLQNAAKHLETAYTKVLSQLFPQENLDILNLYDAKT
TGFENTPEFGYGAYLAKAEAKRELAKLIKRSVEENDFPSSTKSKLIDLLSSWILNHNSVTSIQGNKNINDSVSELKKLLK
LASESSKCASSILSKESLLPFSSSWIIGSDAWSYDLGNSGVHHVLASKKNVNMLIIDSQPYSQVVKDNSTIRKKDIGLYA
MNFGNVYVASVAVYSSYTQLLQALVEAEKFDGPSIVLAYLPYTSENDSPVTVLQETKKAIDSGYWPLYRWNPTLEDQPFK
LDSSRIKKNLQDFLDRENHLTLLSKQNPTFAKNLAQSYGTEIKDQQRRKAKDALSKLLEGLSGPPLTVLFASDGGNAEGL
AKKLARRAKGRGLKSVVLSMDDYPIEDLPNEENIVLITSTAGQGELPQNGRNFWEALKNNAADLDLASVKYSVFGLGDSK
YWPRKEDKHYYNKPSHDLFKKFKLLGASELVPLGQGDDQDPDGFQQGYNEWEPLIWKALGVDNIAVADEPPPITNEDIKI
GSNFLRGTIAEGLKDESTGAISASDQQLTKFHGIYMQDDRDIRDDRKSAGLEPAYSFMVRVRLPGCVSTPEQWLKMDELS
TSYGNDTLKITTRGTFQLHGVIKRNLKPAIRGINSALIDTVAACGDVDRNVVAAALPNNKKIHDEVVEISKAISEHLLPQ
TTAYHEIWLEGADDLDQPGYTEAFENRKEGPRKKKFLISQSTLVDQEPLYGPTYLPRKFKINIAVPPYNDVDVFGHDIGL
VAIVENNELLGFNVFIGGGMGTTHNNTKTYPRTGSLQGYVPKDKIIDVCEKIMLVQRDFGDRKNRKHARLKYTVDDMGND
VYREKVEERLGYKFEQGRPFHFDSNTDQFGWVTDESGLHHFTTFVENGRVEDTPELQFKTGFREIAKMMIGTGGEFRLTA
NQHILISNITDEMLPSIKEVMAKYKLDNTAFSGLRLSSAACVAFPTCGLAMAESERYLPQLITKLEAILEEYGLRHDSIV
MRMTGCPNGCARPWLAEIACVGKAYGAYNLMLGGGHTGERLNKLYRSSLSEEQIIETLKPMFKRWSLERNDGEPFGDWVI
RAGIIAATREGKDFWDNIPEEE

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0051536 iron-sulfur cluster binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features