Protein

MIA_01258_1

Length
530 amino acids


Browser: contig02:185854-187495-

Protein function

EGGNOG:0PH9IGPI14Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity
SGD closest match:S000003774GPI14GPI mannosyltransferase 1
CGD closest match:CAL0000197470GPI14GPI mannosyltransferase 1

Protein alignments

%idAln lengthE-value
A0A0J9X5P2_GEOCN62.670%4421.77e-164Similar to Saccharomyces cerevisiae YJR013W GPI14 Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis OS=Geotrichum candidum GN=BN980_GECA03s06830g PE=4 SV=1
UniRef50_A0A0J9X5P262.670%4423.62e-161Similar to Saccharomyces cerevisiae YJR013W GPI14 Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5P2_GEOCN
MCA_06010_152.865%5411.26e-151MCA_06010_1
A0A167FEK8_9ASCO52.209%4983.64e-146Gpi14p OS=Sugiyamaella lignohabitans GN=GPI14 PE=4 SV=1
A0A060T3S1_BLAAD51.037%4821.04e-136ARAD1C39292p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C39292g PE=4 SV=1
A0A1E3PMC2_9ASCO59.944%3577.65e-128Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82369 PE=4 SV=1
Q6CGA3_YARLI49.772%4381.76e-103YALI0A20922p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A20922g PE=4 SV=2
A0A1E4TEP0_9ASCO41.913%4392.13e-95Glycosyltransferase family 50 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26796 PE=4 SV=1
GPI14_CANAL35.909%4401.71e-75GPI mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GPI14 PE=3 SV=1
GPI14_YEAST37.783%4422.49e-72GPI mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPI14 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0536

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF05007 (Mannosyl_t...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. mobidb-lite (disord...)

Protein sequence

>MIA_01258_1
MGSQDPWQNSAAQDPAQNPASFSSDIDAHSTQASIRKTPSEVDVIFSAEKKSTPSKPSQQPAAKGNEILSFILRPKVAIA
IAIIQRIIIFFWGLYQDANMEPRFTDIDYFVFTDASRFMASTTTKTIDGVPVTVSGTPYDRETYRYTPILAWLLLPTSTW
FFSFGKVLFAVGDIVAGVLILRILIRIKKIEESKAVLYTSAVWLLNPMVSAISTRGSSEGLLGAIVMGFVYAVCARQIAL
AGVVAGFAVHFKIYPIIYIPTVIWSLSSNTPDRSEKEAARDKGRDSIFPASVAKKSAILNFINRDRVVFGVTSAATFLLL
TLWMYKIYGWPFLLHTYLHHLSRIDHRHNYSPYSTLLYMSSSPPATESYAAAIAGSGGSGAIWEVAYKVLSQPSAWAFFP
QLLLSGILLPLLFAKRDVPKTLFLQTFAFVTFNKVCTAQYFMWYMVLLPFYLPSLISYLSSSDDGKKKGRGVLVGLTMAG
LWVGSQVLWVRQAYLVEFMGVSTFYPGLFIATLLFFIVNCLCLGLFIRAM

GO term prediction

Biological Process

GO:0006506 GPI anchor biosynthetic process

Molecular Function

GO:0016758 transferase activity, transferring hexosyl groups

Cellular Component

GO:0016021 integral component of membrane