Protein
MCA_06010_1
Length
602 amino acids
Gene name: GPI14
Description: GPI mannosyltransferase 1
Browser: contigD:3026741-3028794+
RNA-seq: read pairs 1468, FPKM 30.1, percentile rank 52.8% (100% = highest expression)
Protein function
| Annotation: | GPI14 | GPI mannosyltransferase 1 | |
|---|---|---|---|
| KEGG: | K05284 | PIGM | phosphatidylinositol glycan, class M [EC:2.4.1.-] |
| EGGNOG: | 0PH9I | GPI14 | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity |
| SGD closest match: | S000003774 | GPI14 | GPI mannosyltransferase 1 |
| CGD closest match: | CAL0000197470 | GPI14 | GPI mannosyltransferase 1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01258_1 | 55.37% | 540 | 4e-158 | MIA_01258_1 |
| A0A0J9X5P2_GEOCN | 51.23% | 529 | 1e-150 | Similar to Saccharomyces cerevisiae YJR013W GPI14 Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis OS=Geotrichum candidum GN=BN980_GECA03s06830g PE=4 SV=1 |
| UniRef50_A0A0J9X5P2 | 51.23% | 529 | 2e-147 | Similar to Saccharomyces cerevisiae YJR013W GPI14 Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5P2_GEOCN |
| A0A167FEK8_9ASCO | 44.23% | 529 | 2e-127 | Gpi14p OS=Sugiyamaella lignohabitans GN=GPI14 PE=4 SV=1 |
| A0A060T3S1_BLAAD | 41.94% | 527 | 7e-111 | ARAD1C39292p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C39292g PE=4 SV=1 |
| A0A1E3PMC2_9ASCO | 48.39% | 434 | 8e-107 | Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82369 PE=4 SV=1 |
| Q6CGA3_YARLI | 42.52% | 515 | 3e-91 | YALI0A20922p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A20922g PE=4 SV=2 |
| A0A1E4TEP0_9ASCO | 36.02% | 522 | 4e-89 | Glycosyltransferase family 50 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26796 PE=4 SV=1 |
| GPI14_CANAL | 32.51% | 529 | 2e-68 | GPI mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GPI14 PE=3 SV=1 |
| GPI14_YEAST | 33.96% | 530 | 2e-64 | GPI mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPI14 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0405
Protein family membership
- Mannosyltransferase, DXD (IPR007704)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF05007 (Mannosyl_t...)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_06010_1 MKDSLIDNNSSNQQSTNAESVSSTNTMPNKNDITNESTSLKQTDLHQKQSKSSSSISSSSSISDKIFAIIFNPTIAVCIG ILQRIILFFWGLYQDATIEPRFTDIDYFVFTDASRFMVQGGPPAREDIQSLLVSSIPSSFMSFLNTTSLASPNNNPYSPY LRETYRYTPILAWLLIPSHTIYFGFGKILFAFGDIVAGILILKTLQIIRLKYCIQQRQEEEGKGKINHDNKTTSSSEMGN EKWNNSFLFSERAIIIYTCCVWLFNPMVSIISTRGSSEGLLGAIVMVFVYLVYTNHVFLAGVVAGFAVHFKIYPLIYIPT VIWAMSSNNLSSSLSSSTNRKNKINNGRNSIFPQSIVKSLPILNFVNRDRLVFAGASLASFLLFTGWMYALYGPEFLVHT YFHHLSRLDHRHNFSPYSTLLYMSSSPPATAAAAVTAVQNQQQSSSILSWMENHPASSWAFFPQLMLSGVLIPLAFAKRD VAQTMFLQTFAFVTFNKVCTAQYFMWYLVLLPFYLPRLITYLRSNNNNKNNNNNNKNGSAVRATVVGLIMIALWAGGQAL WVRQGYLLEFLGVPTFYPGLFAATLIFFSVNCLILGIFIKAM
GO term prediction
Biological Process
GO:0006506 GPI anchor biosynthetic process
Molecular Function
GO:0016758 transferase activity, transferring hexosyl groups
Cellular Component
GO:0016021 integral component of membrane