Protein
MIA_01227_1
Length
433 amino acids
Browser: contig02:103201-104503+
Protein function
EGGNOG: | 0PHQJ | STR3 | cystathionine beta-lyase |
---|---|---|---|
SGD closest match: | S000003152 | STR3 | Cystathionine beta-lyase |
CGD closest match: | CAL0000187862 | orf19.2092 | Cystathionine beta-lyase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_05189_1 | 83.372% | 433 | 0.0 | MCA_05189_1 |
A0A0J9X7M3_GEOCN | 81.481% | 432 | 0.0 | Similar to Saccharomyces cerevisiae YGL184C STR3 Peroxisomal cystathionine beta-lyase, converts cystathionine into homocysteine OS=Geotrichum candidum GN=BN980_GECA04s04773g PE=3 SV=1 |
Q6CAR4_YARLI | 77.694% | 399 | 0.0 | YALI0D00605p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D00605g PE=3 SV=1 |
A0A1E3PEX0_9ASCO | 76.154% | 390 | 0.0 | Cystathionine beta-lyase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48079 PE=3 SV=1 |
A0A167DB85_9ASCO | 79.737% | 380 | 0.0 | Cystathionine beta-lyase STR3 OS=Sugiyamaella lignohabitans GN=STR3 PE=3 SV=1 |
A0A060T3A5_BLAAD | 75.758% | 396 | 0.0 | ARAD1C31218p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C31218g PE=3 SV=1 |
UniRef50_W6QAK2 | 73.418% | 395 | 0.0 | Cystathionine beta-lyase n=41 Tax=leotiomyceta TaxID=716546 RepID=W6QAK2_PENRF |
Q5ACX5_CANAL | 67.602% | 392 | 0.0 | Cystathionine beta-lyase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2092 PE=3 SV=1 |
A0A1E4TGX8_9ASCO | 69.192% | 396 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31814 PE=3 SV=1 |
STR3_YEAST | 49.757% | 412 | 1.78e-129 | Cystathionine beta-lyase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STR3 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1529
Protein family membership
- Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (IPR000277)
- Cystathionine beta-lyase, eukaryotic (IPR006238)
Domains and repeats
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Domain
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Domain
1
50
100
150
200
250
300
350
400
433
Detailed signature matches
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cd00614 (CGS_like)
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PIRSF001434 (CGS)
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PS00868 (CYS_MET_ME...)
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PF01053 (Cys_Met_Me...)
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-
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SSF53383 (PLP-depen...)
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no IPR
Unintegrated signatures
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mobidb-lite (disord...)
Residue annotation
-
homodimer interfac...
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pyridoxal 5'-phosp...
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substrate-cofactor...
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catalytic residue ...
Protein sequence
>MIA_01227_1 MSTLPTEQLADLAVHSNPEAREGPVPPSPAPSSPRTRRHYSIDTELVFTETTDQYRSSSTPIYQTATFKQESLSNMGEYD YTRSGNPTRTHLERHLARIIGGATRALTVTSGMTALDVITRLLKPGDEVIAGDDLYGGTNRLLKYLSTSGGIIAHHVDTT NVEAVRAVVNEKTAMILLESPTNPLIKIADIPAIAALVHEKNPNALVVADNTMLSPLLMAPLELGADIVYESGTKYLSGH HDIMAGVIAVKDNAVGDRLYFVINASGCGLAPFEAWLLERGIKTLGVRLEKQQRNAQLIAEFLESSGFKVRYPGLKSHPQ YALHWAQASGAGAVLSLETGSVPLSERIIEGTHIWGISVSFGCVNSLISMPCKMSHASIDAKTRAERDFPEDLIRLCVGI ENPDDLIDDLKTALIKAGAVKINNDGSLTRLDL
GO term prediction
Biological Process
GO:0071266 'de novo' L-methionine biosynthetic process
Molecular Function
GO:0003824 catalytic activity
GO:0004121 cystathionine beta-lyase activity
GO:0030170 pyridoxal phosphate binding
Cellular Component
None predicted.