Protein

MIA_01224_1

Length
1,049 amino acids

Browser: contig02:95792-98942+

Protein function

EGGNOG:0PIA1RIA1Elongation factor
SGD closest match:S000005107RIA1Ribosome assembly protein 1
CGD closest match:CAL0000176174RIA1GTPase

Protein alignments

%idAln lengthE-value
A0A0J9XEL4_GEOCN64.459%10720.0Similar to Saccharomyces cerevisiae YNL163C RIA1 Cytoplasmic GTPase involved in biogenesis of the 60S ribosome OS=Geotrichum candidum GN=BN980_GECA13s00989g PE=4 SV=1
MCA_02859_162.196%11110.0MCA_02859_1
A0A1E3PDC0_9ASCO55.904%10840.0p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53670 PE=4 SV=1
A0A060T1Z3_BLAAD56.575%10570.0ARAD1C20746p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20746g PE=4 SV=1
A0A167DC20_9ASCO53.069%10590.0GTPase RIA1 OS=Sugiyamaella lignohabitans GN=RIA1 PE=4 SV=1
UniRef50_A0A167DC2053.069%10590.0GTPase RIA1 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167DC20_9ASCO
Q6C8W8_YARLI51.565%10860.0YALI0D16291p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D16291g PE=4 SV=1
Q59WB7_CANAL47.562%10870.0GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIA1 PE=4 SV=1
A0A1E4TAU3_9ASCO42.337%7960.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32310 PE=4 SV=1
RIA1_YEAST57.204%4651.09e-157Ribosome assembly protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1521

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1049

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
  3. Domain IPR000795
    Transcription factor, GTP-binding domain
    1. PS51722 (G_TR_2)
    2. PF00009 (GTP_EFTU)
    3. PR00315 (ELONGATNFCT)
  4. Domain IPR009000
    Translation protein, beta-barrel domain
    1. SSF50447 (Translati...)
  5. Domain IPR004161
    Translation elongation factor EFTu-like, domain 2
    1. PF03144 (GTP_EFTU_D2)
  6. Domain IPR035647
    EF-G domain III/V-like
    1. SSF54980 (EF-G C-te...)
  7. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  8. Domain IPR014721
    Ribosomal protein S5 domain 2-type fold, subgroup
    1. G3DSA:3.30.23...
  9. Domain IPR000640
    Elongation factor EFG, domain V-like
    1. PF00679 (EFG_C)
    2. SM00838 (EFG_C_a)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.30.10
  2. G3DSA:3.30.70...
  3. G3DSA:3.30.70...
  4. G3DSA:3.40.50...
  5. G3DSA:3.90.14...
  6. PF14492 (EFG_II)
  7. cd01681 (aeEF2_snRN...)
  8. cd01885 (EF2)
  9. cd04096 (eEF2_snRNP...)
  10. cd16261 (EF2_snRNP_III)
  11. cd16268 (EF2_II)

Residue annotation

  1. G1 box cd01885
  2. putative GEF inter...
  3. GTP/Mg2+ binding s...
  4. Switch I region cd...
  5. G2 box cd01885
  6. G3 box cd01885
  7. Switch II region c...
  8. G4 box cd01885
  9. G5 box cd01885
  10. tRNA binding site ...

Protein sequence

>MIA_01224_1
MVNPETLKRLQSHPDLVRNICILAHVDHGKTTLSDSLLASNGIISQNMAGKLRYLDSRPDEQMRGITMESSAISLYFKVA
SKSSSLETKDRPQVKEYLINLIDSPGHIDFSSEVSTASRLCDGALILVDAVEGVLSQTVTVLRQAWIEKLKPVLVINKID
RLVTELRLTPLEAYTHLTRLIEQVNAVMGSFFAVDRMQEDLKWRELQEQKQASDSAEKDEFIEKSDDDLYFSPELNNIIF
ASAIDGWGFNISQFAAIFERKLGIQREKLEKVLWGDYYFDPKTKRVISAGSSAAKNLKNPKPLFVQLVLDNIWKIYESSV
VERDPEQSSKIVSALNLKIPPAIIKAKDGKPLLATIFNQWIPISVSILLSVIEKISPPTIAQRERIPPILESAPGGGDEL
DAGVRKAMLDCDRTGSVVSYVSKVIAIPEEEITRRKIDQEEKENNKTPMSAIQERTRRARELAASLQQGPSDMVAAGGKE
YNDEEDIDDLDAYFNQLKAEAPVIVKEKLIGFARVFSGTLKVGQELYILQPKFDPANPEKHREKVMITDLFLLMGRELVS
LKEVPAGNIVGIGGLDGKILKNGTLVSLEHGEGPNLASTNNIGAPIVRVAVEPVDPTKLDQLEAGLKLLNLSDPMVQVSV
AENGAHILMTAGELHLERCLKDLKDRFAKVDIQASEPIVPYRETILGHKGVVEQTMESNNVDEEKKQEQGVGEIDLGNIK
VKLRVEPLASQVTKFLSDNHDKIETLVERSSKSGLEDAWFEKMFTESVEDAAKNLKNKDNSTRLRNVLALGNIVSLGPRR
TGANILVDQSGLIRHRLLKQKDESKVRFAYEESIVTGFQLATQHGPLTAEPMEGVMVVVESIVEEEENEERDEVEAAGGE
RARNMNVSGRLISATKERILAGFLDWSPRLLLAMYECQIQAPGEVLGKVYGVLSRRRGKVLQEEMREGTPFYLVTASLPV
VEAFGFSDDIRKKTSGAANPQLVFSGFEMVVDEDPFWVPTTEEELEKLGETADRENVAKMYMDKVRRRKGLAVAEKVVAN
AEKQRTLKR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.