Protein

MCA_02859_1

Length
1,108 amino acids

Gene name: RIA1

Description: Ribosome assembly protein 1

Browser: contigB:2540309-2543636+

RNA-seq: read pairs 2112, FPKM 23.5, percentile rank 45.9% (100% = highest expression)

Protein function

Annotation:RIA1Ribosome assembly protein 1
KEGG:K14536RIA1 ribosome assembly protein 1 [EC:3.6.5.-]
EGGNOG:0PIA1RIA1Elongation factor
SGD closest match:S000005107RIA1Ribosome assembly protein 1
CGD closest match:CAL0000176174RIA1GTPase

Protein alignments

%idAln lengthE-value
MIA_01224_161.93%11110.0MIA_01224_1
A0A0J9XEL4_GEOCN58.03%11080.0Similar to Saccharomyces cerevisiae YNL163C RIA1 Cytoplasmic GTPase involved in biogenesis of the 60S ribosome OS=Geotrichum candidum GN=BN980_GECA13s00989g PE=4 SV=1
A0A1E3PDC0_9ASCO51.73%11270.0p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53670 PE=4 SV=1
A0A167DC20_9ASCO51.54%11060.0GTPase RIA1 OS=Sugiyamaella lignohabitans GN=RIA1 PE=4 SV=1
UniRef50_A0A167DC2051.54%11060.0GTPase RIA1 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167DC20_9ASCO
A0A060T1Z3_BLAAD49.73%11140.0ARAD1C20746p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20746g PE=4 SV=1
Q6C8W8_YARLI48.26%11190.0YALI0D16291p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D16291g PE=4 SV=1
Q59WB7_CANAL45.61%11380.0GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIA1 PE=4 SV=1
A0A1E4TAU3_9ASCO39.29%8505e-180Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32310 PE=4 SV=1
RIA1_YEAST57.21%4583e-155Ribosome assembly protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0240
Predicted cleavage: 12

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1108

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
  3. Domain IPR000795
    Transcription factor, GTP-binding domain
    1. PS51722 (G_TR_2)
    2. PF00009 (GTP_EFTU)
    3. PR00315 (ELONGATNFCT)
  4. Domain IPR009000
    Translation protein, beta-barrel domain
    1. SSF50447 (Translati...)
  5. Domain IPR035647
    EF-G domain III/V-like
    1. SSF54980 (EF-G C-te...)
  6. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  7. Domain IPR014721
    Ribosomal protein S5 domain 2-type fold, subgroup
    1. G3DSA:3.30.23...
  8. Domain IPR000640
    Elongation factor EFG, domain V-like
    1. PF00679 (EFG_C)
    2. SM00838 (EFG_C_a)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:2.40.30.10
  3. G3DSA:3.30.70...
  4. G3DSA:3.30.70...
  5. G3DSA:3.40.50...
  6. G3DSA:3.90.14...
  7. PF14492 (EFG_II)
  8. cd01681 (aeEF2_snRN...)
  9. cd01885 (EF2)
  10. cd04096 (eEF2_snRNP...)
  11. cd16261 (EF2_snRNP_III)
  12. cd16268 (EF2_II)
  13. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd01885
  2. putative GEF inter...
  3. GTP/Mg2+ binding s...
  4. Switch I region cd...
  5. G2 box cd01885
  6. G3 box cd01885
  7. Switch II region c...
  8. G4 box cd01885
  9. G5 box cd01885
  10. tRNA binding site ...

Protein sequence

>MCA_02859_1
MSLNPISSHRLQANSDLIRNICILAHVDHGKTTLSDSLLASNGIISQSMAGKLRYLDSRPDEQQRGITMESSAISLHFKV
ATRPTTDESETSKPASPKINEYLINLIDSPGHIDFSSEVSAASRLCDGALVLVDAVEGVLSQTVIVLRQAWVEKLKPVLV
INKIDRLITELQLTPSEAYKHLTRLIEQVNAVMGSFYAGDRMEQDLKWREQHDNQEENQDNYEETSDENLYFSPDKNNVV
FASAIDGWGFNISQFASIYEKKLGIKREKLEKVLWGDFYFDPKTKRVVDAKYFKGNVGSRKPLFVQLVLDNIWKVYESAI
IEPDTEQRAKIVTALNLKVVPQIVKGKDGKQFVSAVFGQWIPLSRSLLLTVIEIIPPPSKAQAIRIPSILDSIPDGNDPT
VVEPKVLKGMLECDKNGPLVSYVSKVIAVPEKELIRKKKEQKELDEASGSPMSAIELRKRKARELAASLQSQPQSGFNSE
RKDEEDDYDEDDLDAYFEKLKLEQEKKDEEQEKLIGFTRVLSGTLSVGQELYLLHPKYDYKKDPTAHRVKVTVTDLFLLM
GRDLIPMTDVPAGNIVGIGGLDGKILKNGTLVSLEHGHGPNLASMSNVRTNKPIVRVAVEPVDPTKLDALEAGLKLLNLS
DPMVQVSVADNGEHILMAAGELHLERCIKDLKERFAKVDIQVSQPIVPYKETIVVPDAEQVQQAYKQLQQQKQQDEEQGN
NKVVPVEDIIGLQEAKIGSTTVKLRILPLLPKVVQFLHDNHHTIESLISLQRQRKDFEKSDENGSKVTELEDKSWCIFES
QFDEMIGEVLSKEMKKSNNLINTKRYELFSNYLKLKNVISFGPKRTGANILIDATPGNILKTRVVQKLVDEGSSSTSRKE
ASFGYEESLITGFQLATQQGPLTAEPVEGVAVLVEYAESANSTSERPDAENEDSEDQQQKKSEVTNSGRMIPVTKEMIHH
GFLAWSPRLLFAMYSCEIQATMDVLGKVYGVITRRRGRVINEEMREGTPFYLIHAKLPVVESFGFSEEIRKKTSGAANPQ
LVFDGFQMVIDQDPFWVPTTEEELEDLGETADRENLAKMYMDSVRRRKGLAVDEKVVNNAEKQRTLKR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.