Protein

MIA_01186_1

Length
879 amino acids

Browser: contig01:3367272-3369912-

Protein function

EGGNOG:0PGDJFG05522.1DNA repair and recombination protein pif1
SGD closest match:S000004526PIF1ATP-dependent DNA helicase PIF1
CGD closest match:CAL0000185430PIF1ATP-dependent DNA helicase PIF1

Protein alignments

%idAln lengthE-value
MCA_04461_154.006%6740.0MCA_04461_1
A0A0J9XD28_GEOCN52.459%6710.0ATP-dependent DNA helicase PIF1 OS=Geotrichum candidum GN=PIF1 PE=3 SV=1
UniRef50_A0A0J9XD2852.459%6710.0ATP-dependent DNA helicase PIF1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XD28_GEOCN
A0A060SZQ7_BLAAD48.917%5541.69e-166ATP-dependent DNA helicase PIF1 OS=Blastobotrys adeninivorans GN=PIF1 PE=3 SV=1
A0A161HKE9_9ASCO42.264%6985.32e-158ATP-dependent DNA helicase PIF1 OS=Sugiyamaella lignohabitans GN=PIF1 PE=3 SV=1
Q6CEU3_YARLI46.060%5711.20e-147ATP-dependent DNA helicase PIF1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PIF1 PE=3 SV=1
PIF1_CANAL44.883%5571.33e-135ATP-dependent DNA helicase PIF1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PIF1 PE=3 SV=2
PIF1_YEAST44.928%5522.57e-130ATP-dependent DNA helicase PIF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PIF1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0462

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 879

Detailed signature matches

  1. Family IPR010285
    DNA helicase Pif1-like
    1. PF05970 (PIF1)
    2. MF_03176 (PIF1)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd00009 (AAA)
  3. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...

Protein sequence

>MIA_01186_1
MSREVKFSKDLDYHLPQEPHGEYPPKNSEFLISESDLISDDSSFFDISECLDNSKVSASTKNGSEILGLNQNETPILPVS
DFQDAQHHVQDIKKTTSSHCSYDDFDVPSDALFSDFFTFSLNSEFPKTEQCINQKSELPSSTPSTKDSKQTSNLVQSDLL
SSPSSSNAFVYNQKPNEIGSESIIKQSQLLLKSQNESNLESLNKTEITSSIPWTDSPQYHIKYTAHDLENISNKKRLEND
LNFDTINTPNHLDHQESNKEAIQSTTTTHKKNLVKTSVWQSRLTGFVSPLEESPIQQSGRSFSTTARIASQNPEKQSSLL
KLSEEQRRVLHFIVNEERNVFFTGAAGTGKSILLRRIINELRRKNKFDGAIAVTASTGLAACNIGGITLHSFCGIGLGRE
PVKNLLKKIRMNRNALKRWKNVKILIIDEISMIDGVLFDKLEELARLIKRNNRPFGGIQVILTGDFFQLPPVFKIEKDYF
QKQMNDENEMKGCLAFHSQTWNTVINTTVELKKVFRQQDDHFSQMLNSIREGQVTNEISSKFRALSRPLLAPHDITPTEL
YPLRRDVDRSNEAMMKKLPGKTKTYTAVDTYNNEYAREYQILNNLICPEVLSLKVGAQVMLIKNIDETLVNGSLGKLLGF
MNEFTFKLVEELPENLANSVITGKISAEEGLETYLNEMKQSSDQTLDQNNILQRLSQLIEDDPYNIPVNYEEIDRDTNYT
INWTRKKELIDKLNDNTKNKGKEWPFVRFIMSDGTTRDILVQAETWDIENIDGKVEASRSQVPLMLAWALSIHKSQGQTL
NWVKVDLSKIFECGQAYVALSRAVKMEGLQVIGFQDSKIRVHPDVIEFYKALPSPLEIPLLETTHKKKNIGPKRRKLEA

GO term prediction

Biological Process

GO:0000723 telomere maintenance
GO:0006281 DNA repair

Molecular Function

GO:0003678 DNA helicase activity

Cellular Component

None predicted.