Protein

MCA_04461_1

Length
943 amino acids

Description: PIF1-like DNA helicase, ATP-dependent DNA helicase

Browser: contigC:3110213-3113045+

RNA-seq: read pairs 455, FPKM 6.0, percentile rank 19.0% (100% = highest expression)

Protein function

Annotation:PIF1-like DNA helicase, ATP-dependent DNA helicase
KEGG:K15255PIF1 ATP-dependent DNA helicase PIF1 [EC:3.6.4.12]
EGGNOG:0PGDJFG05522.1DNA repair and recombination protein pif1
SGD closest match:S000001073RRM3ATP-dependent DNA helicase RRM3
CGD closest match:CAL0000185430PIF1ATP-dependent DNA helicase PIF1

Protein alignments

%idAln lengthE-value
A0A0J9XD28_GEOCN51.58%6340.0ATP-dependent DNA helicase PIF1 OS=Geotrichum candidum GN=PIF1 PE=3 SV=1
UniRef50_A0A0J9XD2851.58%6340.0ATP-dependent DNA helicase PIF1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XD28_GEOCN
MIA_01186_160.85%3782e-152MIA_01186_1
A0A060SZQ7_BLAAD49.73%3703e-108ATP-dependent DNA helicase PIF1 OS=Blastobotrys adeninivorans GN=PIF1 PE=3 SV=1
A0A161HKE9_9ASCO47.57%3913e-106ATP-dependent DNA helicase PIF1 OS=Sugiyamaella lignohabitans GN=PIF1 PE=3 SV=1
Q6CEU3_YARLI48.27%3464e-93ATP-dependent DNA helicase PIF1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PIF1 PE=3 SV=1
PIF1_CANAL46.15%3251e-86ATP-dependent DNA helicase PIF1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PIF1 PE=3 SV=2
RRM3_YEAST42.86%3782e-82ATP-dependent DNA helicase RRM3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRM3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0259

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 943

Detailed signature matches

  1. Family IPR010285
    DNA helicase Pif1-like
    1. PF05970 (PIF1)
    2. MF_03176 (PIF1)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00009 (AAA)
  4. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...

Protein sequence

>MCA_04461_1
MSPIHKSSGSLDSFDDILDDDAFWTEIDNSLLNSGCFGTKPLTDVSSISSASSANKPTETALKNLSCNIQKQYTKTEKVV
RIVEPEKKVSLSINANKHDLVTAPAARLESHVNNDPENQPKNKTTATHTTSTIASKEVQPLNSIIKEDTTQSTFASTPKS
TTSKAKKQAWQSKLTSLFLAPKPDPDQKRTYSTSASSKDSKNSKPQFPPPPASQFFLSEEQKRVLNFIVHEKRNIFFTGA
AGTGKSVLLRNIIKKLRQSHRVPGAVAVTASTGLAACNVGGSTLHSFCGIGLGKDPVDRLLKKIRTNPNALKRWKAVQVL
IIDEVSMIDAALFDKLEEIARTIKRKDIPFGGIQVVLTGDFFQLPPVFDQNLKNDPAYIANDMDGKLAFQSKSWSKVINI
TVELKQVFRQTDNHFAKMLDSIRNGITTPEMVEELQALSRSPENVPKNISPTELFPLRKDVDRANKKMIEMLKGPVHTFK
AIDTYNNPGAKAAQILNNLMCPSILHLKKGAQVMLVKNIDETLVNGSLGEVLGFMSESTFKIVEDMPQSYKDSISVGEKT
IEEVVDKFVNKMDKKVQEKLAEMERNNVPSSDESYIPSSENTDASRIEDSTPNQQQQQQQQSTSDDIITSSNNQDQTTPS
KPPLLLDDPFDIPEEFLTDDDFSFEDQLAKEDKDYVINWARKYQLIESLNESTEQRGAKWPYVRFTIPDGTTRDILVQSE
SWDIEDYDGKVQASRSQVPLILAWALSIHKSQGQTLQWLKVDLSKTFERGQAYVALSRAVSMDGLQVLGFNPSVVRVHPA
VLEFYKSLPSPLEIPYLDEAALAQKLARQAKRKTAKKNRIQTLNDEITNKMVPTPNTTSSGSSSNSNSDKNDDNSVNEEE
TLTTNKKRESRIRNKRRKFWQEQQQQQELQQQQQQDSNNNNNLVTPTVVEKLSTNKTSVYYEN

GO term prediction

Biological Process

GO:0000723 telomere maintenance
GO:0006281 DNA repair

Molecular Function

GO:0003678 DNA helicase activity

Cellular Component

None predicted.