Protein

MIA_01159_1

Length
360 amino acids


Browser: contig01:3310161-3311398-

Protein function

EGGNOG:0PF8JHOG1Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes
SGD closest match:S000004103HOG1Mitogen-activated protein kinase HOG1
CGD closest match:CAL0000197240HOG1Mitogen-activated protein kinase HOG1

Protein alignments

%idAln lengthE-value
MCA_04647_193.931%3460.0MCA_04647_1
A0A0J9X7K5_GEOCN88.825%3490.0Mitogen-activated protein kinase OS=Geotrichum candidum GN=BN980_GECA03s07666g PE=3 SV=1
A0A060T9W0_BLAAD85.920%3480.0Mitogen-activated protein kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22154g PE=3 SV=1
A0A1E3PK72_9ASCO85.755%3510.0Mitogen-activated protein kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46436 PE=3 SV=1
HOG1_YARLI86.628%3440.0Mitogen-activated protein kinase HOG1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HOG1 PE=3 SV=1
UniRef50_A0A0L1JE3483.573%3470.0Mitogen-activated protein kinase n=4 Tax=Aspergillus TaxID=5052 RepID=A0A0L1JE34_ASPNO
HOG1_YEAST82.111%3410.0Mitogen-activated protein kinase HOG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOG1 PE=1 SV=2
HOG1_CANAL78.198%3440.0Mitogen-activated protein kinase HOG1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HOG1 PE=1 SV=2
A0A1E4TJB7_9ASCO77.299%3480.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_432 PE=3 SV=1
A0A161HI89_9ASCO84.641%3060.0Mitogen-activated protein kinase OS=Sugiyamaella lignohabitans GN=HOG1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4025

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 360

Detailed signature matches

    1. PR01773 (P38MAPKINASE)
    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
    1. PS00107 (PROTEIN_KI...)
    1. PS01351 (MAPK)
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF12330 (Haspin_kinase)
  2. cd07856 (STKc_Sty1_...)

Residue annotation

  1. ATP binding site c...
  2. active site cd07856
  3. polypeptide substr...
  4. KIM docking site c...
  5. activation loop (A...

Protein sequence

>MIA_01159_1
MAEFIRTEIFGTCFEITSRYADLNPVGMGAFGLVCSAKDQLTDQNVAIKKILKPFSTPVLAKRTYRELRLLKQLQHENLI
SLRDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDF
GLARIQDTQMTGYVSTRYYRAPEIMLTWQKYDTEVDIWSAGCIFAEMLEGKPLFPGKDHVHQFSIITELLGSPPDDVIDS
IGSENTLRFVRSLPKKEPVPFATNFKNADAEAIDLLEKMLTFDPRKRICAADALAHPYLARYHDPNDEPTAAVAFDWSFN
EADFPIDTWKVMMYSEIVDFHKVDHATLPHNFNGAQTQAT

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.