Protein

MIA_01158_1

Length
1,535 amino acids

Browser: contig01:3305395-3310098+

Protein function

EGGNOG:0PFBGFG05571.1metal resistance protein YCF1
SGD closest match:S000002542YCF1Metal resistance protein YCF1
CGD closest match:CAL0000179549YCF1ATP-binding cassette glutathione S-conjugate transporter

Protein alignments

%idAln lengthE-value
MCA_04646_164.971%15330.0MCA_04646_1
A0A0J9X6N2_GEOCN61.949%14980.0Similar to Saccharomyces cerevisiae YDR135C YCF1 Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family OS=Geotrichum candidum GN=BN980_GECA03s07809g PE=4 SV=1
A0A170QYS1_9ASCO57.381%14970.0ATP-binding cassette glutathione S-conjugate transporter YCF1 OS=Sugiyamaella lignohabitans GN=YCF1 PE=4 SV=1
A0A1E3PNZ7_9ASCO56.780%15340.0Multidrug resistance-associated protein 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81731 PE=4 SV=1
A0A060TAR9_BLAAD56.101%15080.0ARAD1D22132p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22132g PE=4 SV=1
Q6C4N2_YARLI55.126%15020.0YALI0E25069p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E25069g PE=4 SV=1
A0A1D8PR42_CANAL52.219%15320.0ATP-binding cassette glutathione S-conjugate transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YCF1 PE=4 SV=1
UniRef50_G8BKK051.964%15530.0Putative uncharacterized protein n=8 Tax=Debaryomycetaceae TaxID=766764 RepID=G8BKK0_CANPC
YCFI_YEAST51.415%15190.0Metal resistance protein YCF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YCF1 PE=1 SV=2
A0A1E4TMK0_9ASCO51.807%14940.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30952 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0649

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1535

Detailed signature matches

  1. Domain IPR011527
    ABC transporter type 1, transmembrane domain
    1. PS50929 (ABC_TM1F)
    2. PF00664 (ABC_membrane)
    3. SSF90123 (ABC trans...)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR003439
    ABC transporter-like
    1. PF00005 (ABC_tran)
    2. PS50893 (ABC_TRANSP...)
  4. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  5. SITE IPR017871
    ABC transporter, conserved site
    1. PS00211 (ABC_TRANSP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.15...
  3. G3DSA:3.40.50...
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd03244 (ABCC_MRP_d...)
  8. cd03250 (ABCC_MRP_d...)
  9. mobidb-lite (disord...)

Residue annotation

  1. Walker A/P-loop cd...
  2. ATP binding site c...
  3. Q-loop/lid cd03250
  4. ABC transporter si...
  5. Walker B cd03250
  6. D-loop cd03250
  7. H-loop/switch regi...

Protein sequence

>MIA_01158_1
MDQTFFETGASLPFQHASLATHNSQFTFDLLKSLNSSIINPGSKFPASLCHNRLGWGPFDDNFHLTPCFIDGVVLTFPSL
FLLIFGSIQIHLLSKKSLPASRLNWHIILKIALVILQFAFLISLTLINFRSVSSPPYDVSFLSPLLSALCLSVGLALHWI
ERSLFVPSGALLFYWLFEIIATFIKTYHLAFSVNALSSPVFILNAFLFTNSIFIFGLEWIIPKVWASDPAYESIFHKSPL
ESADIFSRITFSWMTPLMKRGYEVFLTAEDLPQLPTESSTGYTSSVFAKHWQQQLLANKHPSLVTALVKSFGSEYFVGGC
FKFIQDVLAFSQPQLLRLLIQFVNDYSLGKPDTNITKGLAISLSMFVLSILQTAALQAYFQRSFNFGLQIRGALTSTVFS
KTLVLSTEDRAKKSTGEIVNLMAIDTQRLQDVTTYLQSLWSAPFQIVLCLVSLHHLVGNAMWAGVIVMVINFIIQTPVAK
KARSLQQKQMKIKDKRVRITQELLNNIKSLKLYTWEIPFTNRLNFIREQQELKNLKVIGELMSVVNFLWTSTPFMVSCST
FAVYSLTSNAPLTTDIVFPCLNLFNLLTFPLAIIPMVLSSVIEANVSAKRIVDYVTMDEIQPDCTIHLDKATSKNEEALT
IEHGTFLWQRKPVVKVALTDINFKAYKNQLNCIVGKVGSGKSALLQAMLGDLHKSEGLVTVKGHIAYVAQGPWIMNATIK
ENILFGSKYDPEFYQLTIESCALLDDLAILPDGDGTFVGEKGISLSGGQKARLSLARAVYARADIYLLDDVLSAVDEHVG
AHIINNVLGDTGLLSTKCRILCTNSIPVLSHADSITMVSNGRIIETGTYNEVMENKGNIYSLLKEFGKRKSPSTPSFSDS
PVPVSGTSTPSTIEDFNSEQPIPIMKRRTSTNTLRRASASSFKRIHIDDEEQNKRTKMTKEHSEQGKVKWEVYKEYARAC
NPTAVFCVFFFMVLASICSVSSGFWLKHWSEENSRTGSNKNLGLYLGVYFAICISASISSVIYTLILMIGCSIQAAKTLH
RRMLNSVIRAPMQWHWSSPIGRTLNRFNNDINRIDSMMARVFSQFFANSLSVTMTLAIIIYNTPPFVLLIGPLGFMYIYY
QRYYLRTSRELKRLESVSKSPIYAHFQETLAGLSTIRAYGQQDRFSFINESSLDFNFQAYFPSISANRWLAVRLEFLGSV
IILCASGLSILMIGTGHVTAGTIGLAMSYALQITQSLNWIVRMNVEVETNIVSVERVLEYSNLPAEAPPIVEGHRPPHGW
PEDGAIQFNHYSARYRPELELILKDINLDIKPEEKIGIVGRTGAGKSSITLALFRIFEPADGDIEIDNVDISKIGLADLR
HGLSIIPQEAQTFEGSLRDNLDPNHEHDDVELWRALELAHLKGHIEKNMEGGLDAVIAEDGANLSFGQKQLLAISRAALT
QSKVLILDEATAAVDVETDQLIQKTIREEFKDRTILTIAHRLNTIIDSDRIAVLSEGRVVEFASPQELLKNKDSLFYSLA
KQGGLVHDDDETITN

GO term prediction

Biological Process

GO:0006810 transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0016021 integral component of membrane