Protein

MCA_04646_1

Length
1,535 amino acids


Gene name: YCF1B

Description: Vacuolar glutathione S-conjugate transporter; ATP-binding cassette (ABC) transporter

Browser: contigC:3590379-3594987+

RNA-seq: read pairs 6893, FPKM 55.4, percentile rank 67.6% (100% = highest expression)

Protein function

Annotation:YCF1BVacuolar glutathione S-conjugate transporter; ATP-binding cassette (ABC) transporter
EGGNOG:0PFBGFG05571.1metal resistance protein YCF1
SGD closest match:S000002542YCF1Metal resistance protein YCF1
CGD closest match:CAL0000179549YCF1ATP-binding cassette glutathione S-conjugate transporter

Protein alignments

%idAln lengthE-value
A0A0J9X6N2_GEOCN69.41%15300.0Similar to Saccharomyces cerevisiae YDR135C YCF1 Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family OS=Geotrichum candidum GN=BN980_GECA03s07809g PE=4 SV=1
MIA_01158_164.91%15330.0MIA_01158_1
A0A170QYS1_9ASCO61.99%15100.0ATP-binding cassette glutathione S-conjugate transporter YCF1 OS=Sugiyamaella lignohabitans GN=YCF1 PE=4 SV=1
A0A060TAR9_BLAAD61.02%15160.0ARAD1D22132p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22132g PE=4 SV=1
A0A1E3PNZ7_9ASCO59.91%15390.0Multidrug resistance-associated protein 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81731 PE=4 SV=1
Q6C4N2_YARLI57.83%15270.0YALI0E25069p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E25069g PE=4 SV=1
UniRef50_K0KDA056.10%15010.0Metal resistance protein n=6 Tax=Saccharomycetales TaxID=4892 RepID=K0KDA0_WICCF
A0A1D8PR42_CANAL55.63%15550.0ATP-binding cassette glutathione S-conjugate transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YCF1 PE=4 SV=1
A0A1E4TMK0_9ASCO56.07%15160.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30952 PE=4 SV=1
YCFI_YEAST54.02%15310.0Metal resistance protein YCF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YCF1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0318

Protein family membership

None predicted.

Domains and repeats

1 200 400 600 800 1000 1200 1400 1535

Detailed signature matches

    1. PF16185 (MTABC_N)
    1. PS50929 (ABC_TM1F)
    2. PF00664 (ABC_membrane)
    3. SSF90123 (ABC trans...)
    1. SSF52540 (P-loop co...)
    1. PF00005 (ABC_tran)
    2. PS50893 (ABC_TRANSP...)
    1. SM00382 (AAA_5)
    1. PS00211 (ABC_TRANSP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. cd03244 (ABCC_MRP_d...)
  3. cd03250 (ABCC_MRP_d...)
  4. mobidb-lite (disord...)

Residue annotation

  1. Walker A/P-loop cd...
  2. ATP binding site c...
  3. Q-loop/lid cd03250
  4. ABC transporter si...
  5. Walker B cd03250
  6. D-loop cd03250
  7. H-loop/switch regi...

Protein sequence

>MCA_04646_1
MDQTVFDIVPLKNISLPITSNSSCLCQSPAGWGPVDNEFNFTPCFIEGVLYNIPNLILIVFGSYQLYSISSHRPHPGSTD
WFFILKLALVVAQIALFLLYSLARVHFSEAPINDIFVLSPLVSFASLFIALSLHYVEHFRSLIPSGSLLFYWLFEILVGS
IKVFSLYSHGAFTNDSHHTILLLLPIFILSNSVIVFFLEWLVPKARMPYARLDEYYPNRSPLEMSDIFSKITFAWMTPLM
KKGYETFLTAEDLPELPKEDTTAYISSQFAKNWQQQLSSKKNPSLTIALGKTFGGLFLTGGFFKVIQDILAFTQPQLLRL
LIKFVTDYSKGKDVNMKQGFAIAIGMFLVSIVQTAALHQYFQRVFEVGMKLKASLTAAIYQKSLVLSTEDRAQKTTGDIV
NLMSVDTQRLQDLTQYGQTLWSGPFQIILCLVSLHNLLGPSMWAGVVIMIIMIPVNATAAKYQKSLQAIQMKNKDSRTRL
TNELLTNIKSLKLYGWEIPFTEKLMNVRDNMELKTLKKIGIFMSLINFLWSSTPYFVSCSTFAIYVLTSDKPLTTDIVFP
ALNLFNLLTFPLAVFPMVISSLIEAQVAVSRLTNFFTMDEVQPDSVIHLEPATAIGEESVVIDNATFLWQRKNGIKVALS
DVNFKAYKGSLSCIVGKVGSGKSAFLQAILGDLHKSEGTVTVKGHVSYVAQVPWIMNATVKENILFGARYDHDFYQQTIE
ACALADDLAILPDGDATTVGEKGISLSGGQKARLSLARAVYARADVYLLDDVLSAVDEHVGAHIIKEVLGEEGLLASKTR
ILCTNSIPVLSHADYISMVSDGRIVETGTRQEIAESKGQIFQLIKDFGKKKATSTPSSSASSTVAPSSTSTPRLGSEDGL
TDNESQEGPVLITSDIDAAKNVIKRRASNQTLRRASMASFKHVTIEDDEVGKRTRMQKEHMEQGQVKWDVYKEYAKACNP
IAVAFFFFFLVASSAFSVASGFWLKHWSEKNTETGSNEHIGLYLGVYFAICISTSLSSVIYTLILMIGCSIQAAQKLHHR
MLLSVIRAPMSFFETTPLGRILNRFSNDIYRIDQLLARVFSQFFSNSIYVCFTLCVIIYNTPPFAILVIPLGLLYLMYQR
YYLRTSRELKRLDSVSKSPIYAHFQETLGGISTIRAYGQQDRFSYINESSMDLNLAAYFPSVSANRWLAVRLEFLGSIII
LCASGLSIAMIRSGNVTAGTIGLAMSYALQITQSLNWIVRMTVEVETNIVSVERVLEYSNLPSEAPAIIEDHRPRATWPE
NGLVRFDHYYTKYRPELDYVLKDINVEIKPQEKIGIVGRTGAGKSSLTMALFRIIEPTDGHIEIDSLNTSTIGLADLRHC
LSIIPQDSQVFEGTLRENLDPNNEHDDTELWRVLELAHLKDHVTNNMENKGLESVISEGGSNFSVGQRQLLSIARALLTP
SKILVLDEATAAVDVHTDKLIQETIRQEFKDRTILTIAHRLNTIADSDRIMVLSEGKVVEFASPQELLSDKNSVFYSLAA
QGGLINNENETSKSD

GO term prediction

Biological Process

GO:0006810 transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0016021 integral component of membrane