Protein

MIA_01151_1

Length
563 amino acids


Browser: contig01:3287234-3289105+

Protein function

EGGNOG:0PK52SWC4Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair
SGD closest match:S000003234SWC4SWR1-complex protein 4
CGD closest match:CAL0000199374SWC4SWR1-complex protein 4

Protein alignments

%idAln lengthE-value
A0A0J9XBV5_GEOCN51.03%5801e-151Similar to Saccharomyces cerevisiae YGR002C SWC4 Component of the Swr1p complex that incorporates Htz1p into chromatin OS=Geotrichum candidum GN=BN980_GECA08s04256g PE=4 SV=1
UniRef50_A0A0J9XBV551.03%5803e-148Similar to Saccharomyces cerevisiae YGR002C SWC4 Component of the Swr1p complex that incorporates Htz1p into chromatin n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBV5_GEOCN
MCA_02310_163.32%3191e-128MCA_02310_1
A0A060TDI5_BLAAD45.86%3622e-91ARAD1D00594p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D00594g PE=4 SV=1
A0A161HK67_9ASCO50.28%3521e-88Swc4p OS=Sugiyamaella lignohabitans GN=SWC4 PE=4 SV=1
SWC4_YARLI42.56%3364e-65SWR1-complex protein 4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SWC4 PE=3 SV=1
SWC4_YEAST36.90%3364e-50SWR1-complex protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWC4 PE=1 SV=1
A0A1E4TDI4_9ASCO38.14%3122e-48Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58621 PE=4 SV=1
A0A1E3PTS2_9ASCO34.52%3101e-38Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_68824 PE=4 SV=1
SWC4_CANAL35.58%2082e-27SWR1-complex protein 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SWC4 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1076

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 563

Detailed signature matches

    1. PF16282 (SANT_DAMP1...)
    1. PF05499 (DMAP1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_01151_1
MSFDVREVLNLPERQPGSGPPPPKRHKPDAPARRLDGMQRELYSLLGENTPPVVVFENRFKERPTWNQKAVPWSLVPFRN
PARNDGLELYHWVLGKHQNDNEDYTFAKYNQKLTIPQFTKEEHDEFLRGMFLKRVLKLNPEWSYEETRYLFDLCDIYGLR
WIVIHDRYYFPTNEKKQIKEESKLNPVKDSAPEEHIEPTESTKPAPIFETPSGSRTIEDLKARFYDVSRKVLKFRHARGD
AMGPTEDELYKQMKYSKESEVKRKQHLESLLSRTPAEIAEEEALVLESRKLETAAELMLLERAEILRVLDAPVTAGKINE
FQTSQELAQLTAQLMSDKSKKRKDLSIPTPGQDSQLLQLQNTHHLQQQALQNQVTAQGIQQTSQLNSHTQLPTQNLTEQK
ATSESRRGNKVKSEFDDQTQSTSTKGTKKGNIKKEKDSNKKIPLTGSSAIAAAIHRKLSSKEEAAYGLSYHDKLNTGVYL
RSSKITTYKQALQSKIHQVLAELGISARPIMPTAKVTAKFDSLQQSISVLLETKKQADKLETEIRVLRAQKAYNSNLNNE
NLQ

GO term prediction

Biological Process

GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

None predicted.

Cellular Component

GO:0005634 nucleus