Protein

MIA_01075_1

Length
1,212 amino acids


Browser: contig01:3084708-3089097-

Protein function

EGGNOG:0PG66MNR2CorA family metal ion transporter
SGD closest match:S000001547MNR2Manganese resistance protein MNR2
CGD closest match:CAL0000200038MNR2Putative Mg(2+) transporter

Protein alignments

%idAln lengthE-value
A0A0J9XIS3_GEOCN66.059%4391.07e-180Similar to Saccharomyces cerevisiae YKL064W MNR2 Vacuolar membrane protein required for magnesium homeostasis OS=Geotrichum candidum GN=BN980_GECA21s01517g PE=4 SV=1
UniRef50_A0A0J9XIS366.059%4392.18e-177Similar to Saccharomyces cerevisiae YKL064W MNR2 Vacuolar membrane protein required for magnesium homeostasis n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIS3_GEOCN
A0A167F3S3_9ASCO60.412%4375.71e-159Putative Mg(2+) transporter MNR2 OS=Sugiyamaella lignohabitans GN=MNR2 PE=4 SV=1
W0TYP7_YARLI61.953%2974.23e-117YALI0B05148p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B05148g PE=4 SV=1
MNR2_YEAST59.683%3151.82e-107Manganese resistance protein MNR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MNR2 PE=1 SV=1
MCA_00527_195.000%1605.65e-98MCA_00527_1
A0A060TBE3_BLAAD83.648%1591.18e-85ARAD1D30888p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30888g PE=4 SV=1
Q59UQ3_CANAL72.327%1591.17e-70Putative Mg(2+) transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MNR2 PE=4 SV=1
A0A1E4TA97_9ASCO69.231%1562.62e-71Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28553 PE=4 SV=1
A0A1E3PMP8_9ASCO60.000%1559.51e-58Cora-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5385 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6174
Predicted cleavage: 13

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF143865 (CorA sol...)
  2. SSF144083 (Magnesiu...)
  3. TRANSMEMBRANE (Tran...)
  4. cd12829 (Alr1p-like)
  5. mobidb-lite (disord...)

Residue annotation

  1. oligomer interface...
  2. metal binding site...
  3. metal binding site...
  4. putative Cl bindin...
  5. hydrophobic gate c...
  6. periplasmic entran...

Protein sequence

>MIA_01075_1
MDPNLFRTTTRNSSSSVPADDDEESLDLDKKLRVNPRSSPPDANISSVGAGIDHGASSGSGVTQGPGNGNQQESDFPDAL
NQRTHRALSISSVETTDLMDHRKHQRASTFTTRPRPGIRSTETFPSSSARLAGSSASSVANARPHGKSTSTSEGASTSKE
PKTGYTGDTPPVNDSENSFTVGRASTLPPVAKSSLSNISSGTPAPPAAVVPSPSSASPISSIPLNSSTSQQPTTKLNNPF
IARRTSISSFNPPANRPGSSRRRLSFTSPVAPGQPRSASPPSSSKVEGFFPMRKSTNDNKSKQNSTCDPPYSGPTSPLLK
DTQSNTYRSISPNTEDRSAVPRQDDTEPNIVPVVSSSFNDDPLAHILRRKSFTSSVNDEHLLGSEPISRRTSQASSLQDV
CLPIDPQIGGMSSPDGRPVFDVSYLEDFANNERRELELLQASVPLEPSVITNHPAYATALRASTSGVPADNISSARFRPY
RVVPWANTSNKLNNATFMSVSSNASGLDGAGIGRRSGADDGLTNFRSRRGKNKYKDPYFTDNPHHKHKGPPLRFTYFRED
MEATIHSPSISGLLQDGQTFDDLFNLTSSAPSPSQTNPNNSVAPSGGHQTPDAAHMTPQHSNHATGGAGTSTPIGTVGPA
AVDAAFSAAANAARHVAAMERNHSRVSSPVTPAGLTAHPIQPSPLNSSFLATTPNAGHQYSASLGGASSLSPGTDGVPSP
RVPQNVPSHVDHAFHHQVSSTVSVAAAAAAAAMANTMSQNNAQQVQQQQQLIQQFDPSPFWLDVMNPTEDEMKVLSKAFG
IHPLTTEDIFLNEPREKVELFRNYYLVCFRSFDINDERSKRSKASRSSEERSATGMAGIDNSGSTLGRKKSVSSLATGKD
LGSGSRRHHTHHHHQQKHLKHHGASRHKSRSKESELTPLNMYIIVFHEGVLTFHFAPTPHPMNVRRRIRLLRDYITLSSD
WISYALIDDITDGFAPMIEAIEDEVNHIEDEILSMHTEWSDDSSSGSDSDDGHRHGYDSSCSEKSNFQDTSDSEAERAAR
RSEKQRRRWKEKGDMLRRIGECRKRIMSVLRLLGSKADVIKGFSKRCNEQWEVAPRYEIGLYLGDIQDHIVTMVQSLNHY
EKLLARSHSNYLAQINIDMTRVNNDMNDVLSKITVLGTIVLPMNIVTGLWGMNVIVPGQNVESLTWFWSITGTLFLFGCI
SFFIARRVYGIA

GO term prediction

Biological Process

GO:0030001 metal ion transport
GO:0055085 transmembrane transport

Molecular Function

GO:0046873 metal ion transmembrane transporter activity

Cellular Component

GO:0016020 membrane