Protein

MCA_00527_1

Length
1,367 amino acids


Gene name: MNR2

Description: Manganese resistance protein MNR2

Browser: contigA:1644660-1648764+

RNA-seq: read pairs 2024, FPKM 18.3, percentile rank 39.0% (100% = highest expression)

Protein function

Annotation:MNR2Manganese resistance protein MNR2
KEGG:K16073ALR magnesium transporter
EGGNOG:0PG66MNR2CorA family metal ion transporter
SGD closest match:S000001547MNR2Manganese resistance protein MNR2
CGD closest match:CAL0000200038MNR2Putative Mg(2+) transporter

Protein alignments

%idAln lengthE-value
MIA_01075_195.06%1624e-98MIA_01075_1
A0A0J9XIS3_GEOCN85.80%1625e-90Similar to Saccharomyces cerevisiae YKL064W MNR2 Vacuolar membrane protein required for magnesium homeostasis OS=Geotrichum candidum GN=BN980_GECA21s01517g PE=4 SV=1
UniRef50_A0A0J9XIS385.80%1621e-86Similar to Saccharomyces cerevisiae YKL064W MNR2 Vacuolar membrane protein required for magnesium homeostasis n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIS3_GEOCN
A0A167F3S3_9ASCO36.88%6401e-85Putative Mg(2+) transporter MNR2 OS=Sugiyamaella lignohabitans GN=MNR2 PE=4 SV=1
A0A060TBE3_BLAAD83.23%1615e-86ARAD1D30888p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30888g PE=4 SV=1
MNR2_YEAST74.38%1602e-74Manganese resistance protein MNR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MNR2 PE=1 SV=1
W0TYP7_YARLI73.75%1608e-75YALI0B05148p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B05148g PE=4 SV=1
Q59UQ3_CANAL71.25%1607e-69Putative Mg(2+) transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MNR2 PE=4 SV=1
A0A1E4TA97_9ASCO67.72%1582e-70Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28553 PE=4 SV=1
A0A1E3PMP8_9ASCO60.00%1559e-58Cora-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5385 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0453

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF01544 (CorA)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF143865 (CorA sol...)
  2. SSF144083 (Magnesiu...)
  3. TRANSMEMBRANE (Tran...)
  4. cd12829 (Alr1p-like)
  5. mobidb-lite (disord...)

Residue annotation

  1. oligomer interface...
  2. hydrophobic gate c...
  3. periplasmic entran...

Protein sequence

>MCA_00527_1
MDQEQYHATTKSANSLEEEANDASLANTRSNSSSSVTDLDTSSFTNNISSTLLDHREIQSRAASVPSKASHKSAFPTISE
ANTLDLNSDKTHNKSPKHSFRNSTGQVNSTGSNTMTRPNNKQTSSPTSNRAFRQPTPFITRRMSGSANLPPPVVLRQVPF
SNPFASDDNSEAHGSDTPVSPSSPPNPGNGRFNKGKTPTSSVPVNTGQQQSPFSASTPSHLSGIRHASTIPLLSDPNTHK
SSYSSFSNDAIDETPTHDSQAGYEYPGNSVGRSHTMADLFRRKSFSSGRSHSRDSRSTNSSHIILGSEPGSRRSSNSSSL
LDVCLPIDSLQGDASQSGRGIFDVSYMDEFAQNERKEWELLQASLIQENNEESQNEILHNGISPMVHTVNEVELDNGGRF
KPYRVVPSWATTSTQKASATTATVGGVTTGANVINASKDGPRSRHSKSKPYDPFFIGLPNSNRRIEGPPLRFTYFREDLE
ATVHSPTIAGLLQEGQTFDDLFNLAPQINVNGSANGGNGTPGVQTLQSGVATGTQTPEPFNTNNGAPLASQLTNTSAHLQ
NHSAAASSAFPSQSNVFPPNNTPPSKTALTRNQQYPASQRNRVSSPLSSGKLSHSPTLNYGIASGTTTPIPPGVQTENNI
DGIIGAMGPGQPTTAHHASSMASSNSQTQQANQQGYDGTTTPGVVYEPSPFWLDVMDPTEEEMKVLSKSFGIHPLTTEDI
FLNEPREKVELFKNYYLVCFRSFDIHDERSKQKKSTRIIEDRHSKKRERRSKYRNHQRQRSNSIRSRNQGYTRYDGGKHR
QSSIITTSNRKKKSDSRYNKRHMSKSRDSELTPLNMYIIVFREGVITFHFSPTPHPMNVRRRIRLLRDYISLSSDWISYA
LIDDITDGFAPMIQSIEDEVNTIEDEILSMHTKWYENEDEEDNDSSGYSSDSSTYSSASNSSALSSASDTTVSSKKGWFR
RKFGKNKKKSRYHRLSMSASEQQRHENYRQSYLDERNNRKARTENFAKESLLRAQDDARLGDDSDVSPVQVEADIENGDL
DTRLLGSEGSNNSGRHDSSHHADGIYDHSKRNEAREEVKRKLDRLYRGSTVNTGILGNSNERGIIIGEDGRETIVPGGFG
DEQQILVDHDEDDEDGEDYGEYGYGYDNRRNDAESRRSLLSKHSSKSSKRSIRSSSSRKSQRSSTSGSTTLTQSSWSSTA
SGRWKEKGDMLRRIGECRKRIMSVLRLLGSKADVIKGFSKRCNEQWEVAPRYEIGLYLGDIQDHIVTMVQSLNHYEKLLA
RSHSNYLAQLNIDMTRVNNEMNDVLSKITILGTIVLPMNIVTGLWGMNVIVPGQDVDSLTWFWSITGTLFLFGCLSFVIA
RKVYGIA

GO term prediction

Biological Process

GO:0030001 metal ion transport
GO:0055085 transmembrane transport

Molecular Function

GO:0046873 metal ion transmembrane transporter activity

Cellular Component

GO:0016020 membrane