Protein

MIA_01070_1

Length
351 amino acids


Browser: contig01:3065123-3066324+

Protein function

EGGNOG:0PFG7CDC28Cell division control protein
SGD closest match:S000000364CDC28Cyclin-dependent kinase 1
CGD closest match:CAL0000191263CDC28Cyclin-dependent kinase 1

Protein alignments

%idAln lengthE-value
MCA_02895_187.797%2950.0MCA_02895_1
A0A0J9XJQ0_GEOCN78.305%2955.61e-179Similar to Saccharomyces cerevisiae YBR160W CDC28 Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK) OS=Geotrichum candidum GN=BN980_GECA24s00846g PE=3 SV=1
A0A060T6N5_BLAAD76.712%2923.59e-173ARAD1B16962p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B16962g PE=3 SV=1
A0A1E4TIQ8_9ASCO76.510%2981.05e-169Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_73709 PE=3 SV=1
CDK1_CANAL77.397%2921.96e-169Cyclin-dependent kinase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC28 PE=1 SV=1
Q6CF29_YARLI76.027%2923.21e-169YALI0B10758p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10758g PE=3 SV=1
A0A1E3PJQ3_9ASCO71.724%2901.40e-161Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52026 PE=3 SV=1
CDK1_YEAST69.831%2951.30e-156Cyclin-dependent kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC28 PE=1 SV=1
UniRef50_P0054669.831%2953.11e-153Cyclin-dependent kinase 1 n=899 Tax=Eukaryota TaxID=2759 RepID=CDK1_YEAST
A0A167FLB6_9ASCO77.056%2311.43e-131Cyclin-dependent serine/threonine-protein kinase CDC28 OS=Sugiyamaella lignohabitans GN=CDC28 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0190

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 351

Detailed signature matches

    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
    1. PS00107 (PROTEIN_KI...)
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd07835 (STKc_CDK1_...)
  2. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd07835
  3. CDK/cyclin interfa...
  4. polypeptide substr...
  5. activation loop (A...

Protein sequence

>MIA_01070_1
MGEIEDYLRLEKVGEGTYGVVYKARDLKNGNRLVALKKIRLEEEDEGVPSTAIREISLLKEMRNENIVALYNIVHTDSQK
LYLVFEFLDMDFKKYIEKIRNGEGLDANVIKRFMSQLVSGICYCHSHRILHRDLKPQNLLIDKEGNLKIADFGLARAFGV
PLRPYTHEVVTLWYRAPEILLGGKQYSVGIDMWSVGCIFAEMITRKPLFPGDSEIDEIFRIFRILGTPNEEIWPGVTTLP
NFKTTFPQWTRRELERNVPGLDDYSGDLLHSFLQYDPAMRMSAKRALQHPYFTDYQTTSSGSGTSSSGNNTASSSSGSNS
IQSQQYHGVSSAAAGAGAGGNSQAAAASLPA

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.