Protein

MIA_01047_1

Length
455 amino acids

Browser: contig01:2995983-2997423-

Protein function

EGGNOG:0PICUZn-dependent hydrolase oxidoreductase family protein
SGD closest match:S000006024FMP30N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial
CGD closest match:CAL0000184399orf19.6061N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D

Protein alignments

%idAln lengthE-value
A0A0J9X306_GEOCN63.305%4660.0Similar to Saccharomyces cerevisiae YPL103C FMP30 Mitochondrial inner membrane protein with a role in maintaining mitochondrial morphology and normal cardiolipin levels OS=Geotrichum candidum GN=BN980_GECA02s01055g PE=4 SV=1
UniRef50_A0A0J9X30663.305%4660.0Similar to Saccharomyces cerevisiae YPL103C FMP30 Mitochondrial inner membrane protein with a role in maintaining mitochondrial morphology and normal cardiolipin levels n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X306_GEOCN
MCA_00760_165.198%4540.0MCA_00760_1
A0A060TFT8_BLAAD61.435%4460.0ARAD1D17072p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17072g PE=4 SV=1
A0A1E3PG31_9ASCO51.789%4750.0Metallo-hydrolase/oxidoreductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47653 PE=4 SV=1
Q6CE36_YARLI50.554%4517.06e-170YALI0B18876p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B18876g PE=4 SV=1
A0A167F556_9ASCO61.111%3246.75e-144Fmp30p OS=Sugiyamaella lignohabitans GN=FMP30 PE=4 SV=1
FMP30_YEAST41.446%4153.55e-112N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FMP30 PE=1 SV=1
Q5ABA9_CANAL39.954%4334.54e-106N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6061 PE=4 SV=1
A0A1E4TBY0_9ASCO42.297%3572.36e-96Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32577 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2662
Predicted cleavage: 16

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 455

Detailed signature matches

  1. Family IPR024884
    N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D
    1. PIRSF038896 (NAPE-PLD)
  2. Domain IPR001279
    Metallo-beta-lactamase
    1. PF12706 (Lactamase_B_2)
    2. G3DSA:3.60.15.10
    3. SSF56281 (Metallo-h...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_01047_1
MKLIFSPWNVSKLRIGVGILAAYTSYAGYIQLKTKYEISERARKEQYEIDVEHLKSQPWPISQYGPLVVGGRYANPFPEY
RPQTIYEFVYCRVIELFHQKPRGGVPANAEEIRRLLPAHRPDFDLLFSTSNDYTHHVSSASTPTLTPTSSSQDPDDSLLP
SIRDRLTLTWLGQSCAFVQCAGVNVLTDPCFGEHLVHPYVGPKRISPPPCHFSELPKIDLVLVSHDHPDHFELETAEQIG
NSATWIVPAGMSKHLKKLGIDNYKELSWWEKTDLPGTDPAEKWEIACTPAMHWSGRNMLDANTTLWCSFVVLRNGKPVFF
HAGDTGYSQPLFDGIKHMYGAGCQVAMIPCGAYTPRWHLRSQHTNPQEAIQIMKDLGAQKLIGVHWGTFVLSDEHFLEPR
ELLHELAKKENRAKDIIAPDFGRTLVFRLHDANEGIDKQEHEVKSIREGKSLLFD

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008270 zinc ion binding
GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity

Cellular Component

None predicted.