Protein

MCA_00760_1

Length
450 amino acids

Gene name: FMP30

Description: N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial

Browser: contigA:2379049-2380472-

RNA-seq: read pairs 1105, FPKM 30.3, percentile rank 53.0% (100% = highest expression)

Protein function

Annotation:FMP30N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial
EGGNOG:0PICUZn-dependent hydrolase oxidoreductase family protein
SGD closest match:S000006024FMP30N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial
CGD closest match:CAL0000184399orf19.6061N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D

Protein alignments

%idAln lengthE-value
MIA_01047_165.71%4550.0MIA_01047_1
A0A0J9X306_GEOCN62.03%4530.0Similar to Saccharomyces cerevisiae YPL103C FMP30 Mitochondrial inner membrane protein with a role in maintaining mitochondrial morphology and normal cardiolipin levels OS=Geotrichum candidum GN=BN980_GECA02s01055g PE=4 SV=1
UniRef50_A0A0J9X30662.03%4530.0Similar to Saccharomyces cerevisiae YPL103C FMP30 Mitochondrial inner membrane protein with a role in maintaining mitochondrial morphology and normal cardiolipin levels n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X306_GEOCN
A0A060TFT8_BLAAD57.18%4390.0ARAD1D17072p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17072g PE=4 SV=1
A0A167F556_9ASCO51.62%4940.0Fmp30p OS=Sugiyamaella lignohabitans GN=FMP30 PE=4 SV=1
A0A1E3PG31_9ASCO49.57%4624e-171Metallo-hydrolase/oxidoreductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47653 PE=4 SV=1
Q6CE36_YARLI51.00%4491e-166YALI0B18876p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B18876g PE=4 SV=1
FMP30_YEAST41.26%4463e-113N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FMP30 PE=1 SV=1
Q5ABA9_CANAL40.13%4511e-105N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6061 PE=4 SV=1
A0A1E4TBY0_9ASCO40.79%4071e-99Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32577 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2705

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 450

Detailed signature matches

  1. Family IPR024884
    N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D
    1. PIRSF038896 (NAPE-PLD)
  2. Domain IPR001279
    Metallo-beta-lactamase
    1. PF12706 (Lactamase_B_2)
    2. G3DSA:3.60.15.10
    3. SSF56281 (Metallo-h...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)

Protein sequence

>MCA_00760_1
MKFLFTWNVNKAKLGFGIIALYTSYAGYVQLKTKYEISERARKQHYLSDVEQLTSSTSQYSPLIIGGRFANPFPEYRPQT
MYEFFFCRIYELFHEKPRGGVPPTLEEVRKQLPAYRPDFELLFNTSRDYQIKNFKNLTDPKPSDTNSGYNHHDSLPDIEN
RMTFTWIGQSCAFIQLAGLNILTDPCFGEHLVHPSLGPKRISPAPCHLSELPKIDLVLVSHDHPDHLELEAAEEIGNSAL
WIVPEGVGKHLKSVGISNFKEMTWWEKKPLIEVPLDTDQSDNKAAVAQVADNASVESASDRWEIACTPAMHWSGRKIFDS
NSTLWCSFLILKNNKPVFFHAGDTGYSYPLFKGIEKIYGPGCKVAMIPCGAYTPRWHLRSQHINPQEAIQVMKDLEAKKM
IGVHWGTFVLSEEHFCEPRDLLNKLAKEENRSEDIIAPEFGKTLVYNLED

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008270 zinc ion binding
GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity

Cellular Component

None predicted.