MIA_01030_1

Protein

Length

303 amino acids

Protein function

EGGNOG:	0Q0XS	PGUG_01902	SNARE domain
CGD closest match:	CAL0000199850	SYN8	Syntaxin

Protein alignments

	%id	Aln length	E-value
MCA_00787_1	44.561%	285	1.57e-45	MCA_00787_1
A0A0J9XAL6_GEOCN	36.786%	280	8.04e-25	Similar to Saccharomyces cerevisiae YAL014C SYN8 Endosomal SNARE related to mammalian syntaxin 8 OS=Geotrichum candidum GN=BN980_GECA06s00868g PE=4 SV=1
UniRef50_A0A0J9XAL6	36.786%	280	1.64e-21	Similar to Saccharomyces cerevisiae YAL014C SYN8 Endosomal SNARE related to mammalian syntaxin 8 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XAL6_GEOCN
A0A060SYN2_BLAAD	32.384%	281	3.79e-19	ARAD1A13442p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A13442g PE=4 SV=1
Q6C5I1_YARLI	27.465%	284	5.33e-16	YALI0E17875p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E17875g PE=4 SV=1
A0A167E2B0_9ASCO	29.966%	297	1.37e-13	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1856 PE=4 SV=1
A0A1E4TC19_9ASCO	30.108%	279	1.60e-13	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58236 PE=4 SV=1
A0A1D8PSE4_CANAL	26.280%	293	2.29e-10	Syntaxin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SYN8 PE=4 SV=1
A0A1E3PGP4_9ASCO	26.462%	325	4.22e-10	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52239 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0299

Protein family membership

None predicted.

Domains and repeats

Domain
208 - 301
Target SNARE coiled-coil homology domain (IPR000727)

1 50 100 150 200 250 303

Detailed signature matches

IPR000727

Target SNARE coiled-coil homology domain
1. PF05739 (SNARE)
  
  259 - 301
  
  Pfam
  PF05739 (SNARE)
2. PS50192 (T_SNARE)
  
  213 - 275
  
  PROSITE profiles
  PS50192 (T_SNARE)
3. SM00397 (tSNARE_6)
  
  208 - 275
  
  SMART
  SM00397 (tSNARE_6)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

303 - 303

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.5.110

220 - 279

GENE3D
G3DSA:1.20.5.110 (G3DSA:1.20.5.110)
NON_CYTOPLASM... (N...)

1 - 282

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SSF58038 (SNARE fus...)

204 - 275

SUPERFAMILY
SSF58038 (SNARE fusion complex)
TMhelix

283 - 302

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

283 - 302

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
cd15859 (SNARE_SYN8)

216 - 283

CDD
cd15859 (SNARE_SYN8)
mobidb-lite (disord...)

134 - 202

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

heterotetramer int...

220D

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

221Q

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

222H

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

223L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

225R

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

226L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

227A

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

229S

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

230V

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

231S

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

233Q

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

234H

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

236L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

237S

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

238L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

239H

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

240I

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

241G

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

243E

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

244L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

246T

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

247H

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

250L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

251L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

253E

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

254V

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

255H

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

257F

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

258A

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

259D

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

261S

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

262H

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

264R

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

265L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

268A

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

269K

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

271R

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

272L

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)

274K

heterotetramer interface
220D, 221Q, 222H, 223L, 225R, 226L, 227A, 229S, 230V, 231S, 233Q, 234H, 236L, 237S, 238L, 239H, 240I, 241G, 243E, 244L, 246T, 247H, 250L, 251L, 253E, 254V, 255H, 257F, 258A, 259D, 261S, 262H, 264R, 265L, 268A, 269K, 271R, 272L, 274K
CDD
cd15859 (SNARE_SYN8)
zero layer cd15859

247H

zero layer
247H
CDD
cd15859 (SNARE_SYN8)

Protein sequence

>MIA_01030_1
MVLSELSRLEYKLEDLVDQARMSVDERNRTLRLDLKPVPSSERDLEKTLSTTVESISELRDLVVDSNKPADSKRRNELLE
RFTANYNEILQQYKNDPNLKTNFKELVLERPQAKSKHVRFRDNLVDVKNYNPAHSSSAAGSADPAAATSSASASDSNGGS
QGVRSLLFGEPPYSDDPSKQSYRDSDDSDDSDGSGPLLPRVDTNNHQHLRQQQLVLNEQDQHLDRLAESVSRQHMLSLHI
GDELETHLDLLDEVHGFADRSHNRLATAKKRLTKFFKKARENGSVLTIAILFIIFIILLIVLK

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_01030_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component