MCA_00787_1

Protein

Length

299 amino acids

RNA-seq: read pairs 2383, FPKM 98.1, percentile rank 78.3% (100% = highest expression)

Protein function

KEGG:	K08501	STX8	syntaxin 8
EGGNOG:	0Q0XS	PGUG_01902	SNARE domain
CGD closest match:	CAL0000199850	SYN8	Syntaxin

Protein alignments

	%id	Aln length	E-value
MIA_01030_1	44.21%	285	1e-45	MIA_01030_1
A0A0J9XAL6_GEOCN	34.53%	278	2e-26	Similar to Saccharomyces cerevisiae YAL014C SYN8 Endosomal SNARE related to mammalian syntaxin 8 OS=Geotrichum candidum GN=BN980_GECA06s00868g PE=4 SV=1
UniRef50_A0A0J9XAL6	34.53%	278	4e-23	Similar to Saccharomyces cerevisiae YAL014C SYN8 Endosomal SNARE related to mammalian syntaxin 8 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XAL6_GEOCN
A0A060SYN2_BLAAD	33.93%	280	1e-23	ARAD1A13442p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A13442g PE=4 SV=1
Q6C5I1_YARLI	32.10%	271	3e-22	YALI0E17875p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E17875g PE=4 SV=1
A0A167E2B0_9ASCO	29.55%	291	8e-18	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1856 PE=4 SV=1
A0A1E3PGP4_9ASCO	57.14%	56	2e-11	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52239 PE=4 SV=1
A0A1E4TC19_9ASCO	48.21%	56	3e-10	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58236 PE=4 SV=1
A0A1D8PSE4_CANAL	24.13%	286	1e-06	Syntaxin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SYN8 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0006

Protein family membership

None predicted.

Domains and repeats

Domain
204 - 271
Target SNARE coiled-coil homology domain (IPR000727)

1 50 100 150 200 250 299

Detailed signature matches

IPR000727

Target SNARE coiled-coil homology domain
1. PS50192 (T_SNARE)
  
  209 - 271
  
  PROSITE profiles
  PS50192 (T_SNARE)
2. SM00397 (tSNARE_6)
  
  204 - 271
  
  SMART
  SM00397 (tSNARE_6)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

299 - 299

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.5.110

216 - 275

GENE3D
G3DSA:1.20.5.110 (G3DSA:1.20.5.110)
NON_CYTOPLASM... (N...)

1 - 278

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SSF58038 (SNARE fus...)

200 - 270

SUPERFAMILY
SSF58038 (SNARE fusion complex)
TMhelix

279 - 298

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

279 - 298

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
cd15859 (SNARE_SYN8)

217 - 279

CDD
cd15859 (SNARE_SYN8)
mobidb-lite (disord...)

128 - 196

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

heterotetramer int...

217S

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

218H

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

219L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

221R

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

222L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

223A

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

225S

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

226V

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

227S

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

229Q

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

230H

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

232L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

233S

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

234L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

235Q

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

236I

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

237N

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

239E

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

240L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

242D

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

243H

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

246L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

247L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

249E

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

250M

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

251D

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

253F

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

254T

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

255D

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

257S

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

258Q

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

260R

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

261L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

264A

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

265K

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

267R

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

268L

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)

270T

heterotetramer interface
217S, 218H, 219L, 221R, 222L, 223A, 225S, 226V, 227S, 229Q, 230H, 232L, 233S, 234L, 235Q, 236I, 237N, 239E, 240L, 242D, 243H, 246L, 247L, 249E, 250M, 251D, 253F, 254T, 255D, 257S, 258Q, 260R, 261L, 264A, 265K, 267R, 268L, 270T
CDD
cd15859 (SNARE_SYN8)
zero layer cd15859

243H

zero layer
243H
CDD
cd15859 (SNARE_SYN8)

Protein sequence

>MCA_00787_1
MKQDSADVSKIRSKLELLYDQAQISVDERNRLRSMDMEPTPSTDHELENSLQALAKSIQDVQQDKFSIPDNKTRETLVAE
YVENYNDLLALYRLDPEISTTHLELKLETSQPKSKHVRFRDNLVEVSDGIPISQPSKSSKNSTPKSSIKNSPTSSITAED
IRKNLFNAPYKDDPDEASLGRYRDDDGSSKNKLPPVDTMNNQHLHQAQLLQLQDQDSHLDRLAQSVSRQHHLSLQINEEL
EDHVQLLDEMDVFTDSSQSRLSLAKQRLTTFSRKAKDNGSILTIVILFLTLIILLIVLK

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_00787_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component