Protein
MIA_00970_1
Length
457 amino acids
Browser: contig01:2761167-2763186+
Protein function
| EGGNOG: | 0PHPD | BUR1 | Serine threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2 RAD6 ubiquitin- conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity) |
|---|---|---|---|
| SGD closest match: | S000005952 | PHO85 | Cyclin-dependent protein kinase PHO85 |
| CGD closest match: | CAL0000191263 | CDC28 | Cyclin-dependent kinase 1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01357_1 | 54.211% | 190 | 2.60e-56 | MCA_01357_1 |
| UniRef50_K8FCY1 | 40.136% | 147 | 1.83e-26 | Uncharacterized protein n=1 Tax=Bathycoccus prasinos TaxID=41875 RepID=K8FCY1_9CHLO |
| A0A0J9XEC5_GEOCN | 30.970% | 268 | 7.32e-28 | Similar to Saccharomyces cerevisiae YGR040W KSS1 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response OS=Geotrichum candidum GN=BN980_GECA10s01825g PE=4 SV=1 |
| A0A1E3PJF6_9ASCO | 36.486% | 148 | 7.58e-26 | Negative regulator of the PHO system OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_42361 PE=3 SV=1 |
| Q6CF29_YARLI | 30.824% | 279 | 7.32e-25 | YALI0B10758p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10758g PE=3 SV=1 |
| A0A167DPB0_9ASCO | 27.007% | 274 | 2.22e-24 | Serine/threonine protein kinase RIM11 OS=Sugiyamaella lignohabitans GN=RIM11 PE=3 SV=1 |
| A0A060T4L0_BLAAD | 26.740% | 273 | 2.83e-24 | ARAD1B04290p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B04290g PE=3 SV=1 |
| A0A1E4TIQ8_9ASCO | 45.455% | 121 | 5.48e-24 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_73709 PE=3 SV=1 |
| CDK1_CANAL | 30.935% | 278 | 2.51e-23 | Cyclin-dependent kinase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC28 PE=1 SV=1 |
| PHO85_YEAST | 38.017% | 121 | 5.08e-23 | Cyclin-dependent protein kinase PHO85 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHO85 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3268
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
457
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
mobidb-lite (disord...)
Protein sequence
>MIA_00970_1 MSDRYQFLEWVGRGSFAKVRHAKRTYDGGDVAIKEIMRSSFVRDREIYLLDRLWHRNIVNLLDIIYLDAPPPLPLEPTSS SGGAGGSTTPTPSAPGTAASGPHRNYHHRQQQQQLADPPASEEVIPLLVLDWAPITLDSLMDAFRLPFDIFQLKCFAWQL IEAVAFLHEHGIVHRDIAPSNILLTTEGIEDGHLTPNVCTLWYRAPEILQHRDYSYPVDMWSYGCVIMELVLGRPLLPGN SEVDELDRIFRFFEGAPDGPDPALRAPILPSSSTSSIAPSAGSQNPARPSSSSRPLSSRPSSSSSSTSISSAVSSSSSSS SSHHHHHHHSHQGSRPPAHFLHTRAAYKRARPMDVRERNPQQFSAVQRLLYHLRPVSASHSSSQSSKPPSKSSTSASSSS SDTQIVPVDHNFISLMEGILTFDPDNRIYAKDAISHGFFYKEPYPCTPIELLARLNA
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.