Protein
MCA_01357_1
Length
569 amino acids
Description: Putative protein kinase
Browser: contigA:4234071-4236266+
RNA-seq: read pairs 943, FPKM 20.4, percentile rank 42.0% (100% = highest expression)
Protein function
| Annotation: | Putative protein kinase | ||
|---|---|---|---|
| EGGNOG: | 0PHPD | BUR1 | Serine threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2 RAD6 ubiquitin- conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity) |
| SGD closest match: | S000005952 | PHO85 | Cyclin-dependent protein kinase PHO85 |
| CGD closest match: | CAL0000191033 | CRK1 | Serine/threonine-protein kinase BUR1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00970_1 | 54.21% | 190 | 3e-57 | MIA_00970_1 |
| A0A0J9XEC5_GEOCN | 37.36% | 174 | 3e-25 | Similar to Saccharomyces cerevisiae YGR040W KSS1 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response OS=Geotrichum candidum GN=BN980_GECA10s01825g PE=4 SV=1 |
| UniRef50_A0A0J9XEC5 | 37.36% | 174 | 5e-22 | Similar to Saccharomyces cerevisiae YGR040W KSS1 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XEC5_GEOCN |
| BUR1_CANAL | 32.18% | 174 | 2e-18 | Serine/threonine-protein kinase BUR1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CRK1 PE=3 SV=3 |
| PHO85_YEAST | 31.64% | 177 | 7e-18 | Cyclin-dependent protein kinase PHO85 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHO85 PE=1 SV=2 |
| A0A060TBI0_BLAAD | 28.98% | 176 | 7e-17 | ARAD1B07898p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B07898g PE=4 SV=1 |
| PHO85_YARLI | 31.61% | 174 | 1e-16 | Negative regulator of the PHO system OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PHO85 PE=3 SV=1 |
| A0A167DX62_9ASCO | 32.18% | 174 | 1e-15 | Cyclin-dependent serine/threonine protein kinase SGV1 OS=Sugiyamaella lignohabitans GN=SGV1 PE=4 SV=1 |
| A0A1E3PJF6_9ASCO | 29.89% | 174 | 6e-16 | Negative regulator of the PHO system OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_42361 PE=3 SV=1 |
| A0A1E4TGD2_9ASCO | 29.31% | 174 | 7e-16 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12500 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1093
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
569
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_01357_1 MYEKYEFLEWVGKGSFANVRHGIRTHDNRDVAIKEIKRSSFVRNREIFLLDKLWHRNIVNLLDIIDLEIKRPSPPNYNDI NGNSNRTDQLPPEENSIPLLVLDWAPLSLEALLDTLRVPFDIPQLKHFAWQLIEGIAYIHEHGIVHRDLQPGNILITDSG IVKISDFGSATLLSRYYYSSYPQSHHYRQSSFEQPPPAYNSSSSSEPFNNTPFQTPYKSSSSSRYNSNNHYYEPQPNTPV SSTSPFIANPPSASSNFSLSSSSSYMSLRSSNSVPSYATSLSTPTDSYHHHHFDDYHSAQYPKRSISHIVEKQKRNYSFC SINLPESVVEFEEDGNLTPQVCTLWYSAPEMLKLKDYSYAVDIWSYGCILMECSLGYPLFDGADVQSQIKKIEDFFQYDE ELIKTVVKKTSMESLADKDSENEDDNKENYHNNQQHKRKDSLESQPPHSKRLKRNSTSSTHSTSSTTSSSSHYHHYHNPH DTSSLLSKVRPEDVRERTEDQQSALEKLLRKKSKIPVDYNFIRLIEKILQYTPMTRLYASVAISHGFFYKQPYPCTAREF IEKIKMSRR
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.