Protein

MIA_00963_1

Length
861 amino acids

Browser: contig01:2728714-2731300+

Protein function

EGGNOG:0PHCSSEY1Cooperates with the reticulon proteins and tubule- shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization (By similarity)
SGD closest match:S000005691SEY1Protein SEY1
CGD closest match:CAL0000187915SEY1Protein SEY1

Protein alignments

%idAln lengthE-value
MCA_04538_164.748%8340.0MCA_04538_1
A0A0J9XCL5_GEOCN60.193%8290.0Protein SEY1 OS=Geotrichum candidum GN=SEY1 PE=3 SV=1
UniRef50_A0A0J9XCL560.193%8290.0Protein SEY1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCL5_GEOCN
A0A161HFN0_9ASCO49.815%8090.0Protein SEY1 OS=Sugiyamaella lignohabitans GN=SEY1 PE=3 SV=1
A0A060T1C3_BLAAD51.950%7950.0Protein SEY1 OS=Blastobotrys adeninivorans GN=SEY1 PE=3 SV=1
A0A1E3PT14_9ASCO47.893%7830.0Protein SEY1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=SEY1 PE=3 SV=1
SEY1_YARLI44.819%8010.0Protein SEY1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SEY1 PE=3 SV=1
SEY1_CANAL39.236%7854.03e-173Protein SEY1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEY1 PE=1 SV=2
SEY1_YEAST37.277%7863.36e-168Protein SEY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEY1 PE=1 SV=1
A0A1E4THN7_9ASCO47.002%4173.98e-115Protein SEY1 OS=Tortispora caseinolytica NRRL Y-17796 GN=SEY1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0109

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 861

Detailed signature matches

  1. Family IPR008803
    RHD3/Sey1
    1. PF05879 (RHD3)
    2. MF_03109 (Sey1)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR030386
    GB1/RHD3-type guanine nucleotide-binding (G) domain
    1. PS51715 (G_GB1_RHD3)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:3.40.50...
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd01851 (GBP)
  8. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd01851
  2. GTP/Mg2+ binding s...
  3. Switch I region cd...
  4. G2 box cd01851
  5. G3 box cd01851
  6. Switch II region c...
  7. G4 box cd01851
  8. G5 box cd01851

Protein sequence

>MIA_00963_1
MSSDHSIPAHLAPSPYTGAGTSYSAQPTIPPASSSSSPLPPTPNQINKDNTTFQIIDEDKKFNPHLLEYFRKAAIDKCGL
NYHIVSVFGSQSTGKSTLLNALFGTRFDVMNEIQRQQTTKGIWMAAATNTSAQPIFSSSASFSSQSSSPNLLIMDVEGTD
GRERGEDQDFERKSALFALATSEVLIVNMWENQVGLYQGANMALLKTVFEVNLALFNTSAKASRSLILFVIRDHIGTTPL
ANLRATVTADLKRIWESLSKPPSAAHSSIEDFFDLQFCALPHKILMAEQFSAQTAALSQQFTQPQAPGYLFKQEYHRGVP
LDGWPMYTEQIWEQIEQNKDLDLPTQQTLVARFRCEEIAAQAWQQFEAGLLEAQHESNNALGGPAVVQDFGSIISNIRGG
TMELYDSLASRYAKAVYMAKREDLLSKIDTRLTNLYKAQLIALHKHAVSVFKSLIKAASSKQHHTSSLPFIEVLHRGRTT
SIEAFVSGARKSSVDASVFTYNEELLALEQELAAIEESAKAAEIKRISSVAHKKITKSFGTDLEAYFIEPTQDTWDKVLV
YFNNTVMFALSAVAKRDIDSDTYDFGVGGNSQENARGVGEIRRGAWISLDHQLKQVTRDDNVLFRLRERFEDLFKYDSSG
VPIVWKAGDNIEGPYLSARDEALKLLPIFATARLKNGSLVVPDVDSSKVIDLTDDDHHSVHDDDDDSALDADTFPYRISP
TKEQDLSKRFKKQADAAFVEAKRSTTQLTKQVPFYMIVLLVVLGWNEFMAVLRNPFFFLLLLLGGAGLYVTYTLNMWGPI
LSVTNAMMDRTVEVGKQRLREILEVPEGSSVELRGPTQERRRKVEEIPLQEIKTSNVTDKE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

None predicted.