Protein

MCA_04538_1

Length
873 amino acids

Gene name: SEY1

Description: Protein SEY1

Browser: contigC:3314262-3316884-

RNA-seq: read pairs 6060, FPKM 85.7, percentile rank 76.4% (100% = highest expression)

Protein function

Annotation:SEY1Protein SEY1
EGGNOG:0PHCSSEY1Cooperates with the reticulon proteins and tubule- shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization (By similarity)
SGD closest match:S000005691SEY1Protein SEY1
CGD closest match:CAL0000187915SEY1Protein SEY1

Protein alignments

%idAln lengthE-value
MIA_00963_165.19%8360.0MIA_00963_1
A0A0J9XCL5_GEOCN57.31%8550.0Protein SEY1 OS=Geotrichum candidum GN=SEY1 PE=3 SV=1
UniRef50_A0A0J9XCL557.31%8550.0Protein SEY1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCL5_GEOCN
A0A161HFN0_9ASCO50.60%8280.0Protein SEY1 OS=Sugiyamaella lignohabitans GN=SEY1 PE=3 SV=1
A0A060T1C3_BLAAD51.47%8160.0Protein SEY1 OS=Blastobotrys adeninivorans GN=SEY1 PE=3 SV=1
A0A1E3PT14_9ASCO47.24%7980.0Protein SEY1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=SEY1 PE=3 SV=1
SEY1_YARLI43.67%8610.0Protein SEY1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SEY1 PE=3 SV=1
SEY1_CANAL38.48%8036e-178Protein SEY1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEY1 PE=1 SV=2
SEY1_YEAST36.29%8138e-169Protein SEY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEY1 PE=1 SV=1
A0A1E4THN7_9ASCO42.80%4792e-112Protein SEY1 OS=Tortispora caseinolytica NRRL Y-17796 GN=SEY1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0408

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 873

Detailed signature matches

  1. Family IPR008803
    RHD3/Sey1
    1. PF05879 (RHD3)
    2. MF_03109 (Sey1)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR030386
    GB1/RHD3-type guanine nucleotide-binding (G) domain
    1. PS51715 (G_GB1_RHD3)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:3.40.50...
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd01851 (GBP)
  8. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd01851
  2. GTP/Mg2+ binding s...
  3. Switch I region cd...
  4. G2 box cd01851
  5. G3 box cd01851
  6. Switch II region c...
  7. G4 box cd01851
  8. G5 box cd01851

Protein sequence

>MCA_04538_1
MESSLDHSQAPVPNSYASSNGSSALGQLDDETFQVIDENKHYNSNVSAYFKAINIDKCGLNYHIVSVFGSQSTGKSTLLN
ALFGTKFDVMNEVQRRQTTKGIWMAHCRKKAVAENGPSLNTAASQESAEPNLLIMDVEGTDGRERGEDQDFERKSALFAL
ATSEVLIVNMWENQVGLYQGANMGLLKTVFEVNLSLFHTSAQKNRSLIMFVIRDHIGTTPLSNLQNTIVADLNRIWESLS
KPEAAATSKLGDFFDLQFFTLPHKILMPDQFASQTATLSQYFINTSSYNYLFKPEYHRNVPLDGWPMYSQQIWEQIEQNK
DLDLPTQQTLVARFRCEEIASQSWQTFESGLVSAQKDLDNSLGGPEVVDNFGEIVSSLRNGTLELYDSLASRYAKPVYLD
KRDDLQAKIDTRLNNLYKAQLLALHKSSVKLFKTLIKAAQRQASTSNSVPFIDVLDGGNEKALDYFLTGAKKSSVDSSVF
TYDEEYDALKRELADISSQAKAAEIKRISTVAIKRIKTAFDNDLETYFSEPKDDTWDQILTFFNNTVFFALTSVTTKYKT
STTNSKTDASENGYDFGVGGNDIDNAKGARDIRRKAWLLLDSELKQITRDENVLFRLREKFEDLFKYDSNGVPIVWKAGD
DIETPYVKARDESLKMLPIFATARLKNGELLVPDLPKIEDDLNSNLGRAEEIEDEDKSEEHDEEESRLDPEAFPYRITSA
KEAELSKRFKKQVDASFIEAKRSTTQMAHKVPFYMIILIVVLGWNEFMAVLRNPFLFLFALFAGAGAYVAFTLNLWGPIL
SVSNAMFERSIEIGKEKLRDFLEVPEGAEIGIRRREDVALELPGKPKTNGSAVEEIPLQDMKKPISSVETSEY

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

None predicted.