Protein

MIA_00959_1

Length
558 amino acids

Browser: contig01:2712424-2714101-

Protein function

EGGNOG:0PIG8ERG12mevalonate kinase
SGD closest match:S000004821ERG12Mevalonate kinase
CGD closest match:CAL0000186221ERG12Mevalonate kinase

Protein alignments

%idAln lengthE-value
MCA_04033_152.905%4826.26e-141MCA_04033_1
A0A0J9XG91_GEOCN61.455%2759.71e-98Mevalonate kinase OS=Geotrichum candidum GN=BN980_GECA15s03178g PE=3 SV=1
UniRef50_A0A0J9XG9161.455%2751.99e-94Mevalonate kinase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XG91_GEOCN
A0A167CPL2_9ASCO44.485%2721.92e-62Mevalonate kinase OS=Sugiyamaella lignohabitans GN=ERG12 PE=3 SV=1
A0A1E3PMY2_9ASCO44.322%2731.68e-57Mevalonate kinase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45732 PE=3 SV=1
A0A1D8PEL1_CANAL43.793%2909.36e-54Mevalonate kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG12 PE=3 SV=1
Q6CEF6_YARLI38.351%2791.06e-46Mevalonate kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B16038g PE=3 SV=1
A0A060TB02_BLAAD39.929%2831.74e-44Mevalonate kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30602g PE=3 SV=1
KIME_YEAST39.695%2621.90e-40Mevalonate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG12 PE=1 SV=1
A0A1E4TM26_9ASCO35.088%2851.11e-33Mevalonate kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_93700 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3047

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 558

Detailed signature matches

  1. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  2. Domain IPR014721
    Ribosomal protein S5 domain 2-type fold, subgroup
    1. G3DSA:3.30.23...
  3. Domain IPR006204
    GHMP kinase N-terminal domain
    1. PF00288 (GHMP_kinas...)
  4. Domain IPR013750
    GHMP kinase, C-terminal domain
    1. PF08544 (GHMP_kinas...)
    2. SSF55060 (GHMP Kina...)
    3. G3DSA:3.30.70...
  5. SITE IPR006203
    GHMP kinase, ATP-binding, conserved site
    1. PS00627 (GHMP_KINAS...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00959 (MEVGALKINASE)
  2. mobidb-lite (disord...)

Protein sequence

>MIA_00959_1
MTVSLLPTFVASAPGKVIIFGEHAAVYNKPAIAAALSLRTYLYVTPNDPVSDNVIRLEFPDVGLKFECPAASLPWHLVQK
LDDTPPGSRPSSASSSSTTSTAAAQSLDELNLDQHVVSELHKILMPKVTNSFQYAALLAFFYLYLHICDPSTPVHTFVTK
STLPVGAGLGSSATYAVCLSTAFLTLTKHLSVPTVEEEPPLSRATTREDKNNTESVFDKAASDLLSTPPITPTFESSTPP
PSNKIDGTSTSPSATTDATATEAARATAAAALASTTSVLCLGNADHDLINKWSYIGEKCLHGNPSGIDNTVACRGGAVLF
QRPSTLIPMKRFPALKLLLTNTKHPRRTKDLVARVGDLYETFQSGTQSILDAIEHVTQEAFVLLGSAERPSEKCHEETPG
TPSKKLGLALPIKTVGESPDAVKRLLQLIRINHGLLVSLGVSHPKLEKVKSIGDQLHIGETKLTGAGGGGCAITLLHVDD
VDTAGSDADSAAATIDERLEEFRARLESTKNGFEIFETVLGGPGVGLATGSDVEHLTHDEFLSLNRAQLESFDWKYWG

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding

Cellular Component

None predicted.