MIA_00922_1

Protein

Length

1,671 amino acids

Protein function

EGGNOG:	0PHIQ	PGUG_04818	calcium calmodulin-dependent protein kinase
SGD closest match:	S000000931	SAK1	SNF1-activating kinase 1
CGD closest match:	CAL0000198568	orf19.3840	Serine/threonine protein kinase

Protein alignments

	%id	Aln length	E-value
MCA_05567_1	72.028%	429	9.23e-178	MCA_05567_1
A0A0J9XKL3_GEOCN	58.838%	396	4.98e-136	Similar to Saccharomyces cerevisiae YER129W SAK1 Upstream serine/threonine kinase for the SNF1 complex OS=Geotrichum candidum GN=BN980_GECA23s01187g PE=4 SV=1
UniRef50_A0A0J9XKL3	58.838%	396	1.02e-132	Similar to Saccharomyces cerevisiae YER129W SAK1 Upstream serine/threonine kinase for the SNF1 complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKL3_GEOCN
A0A167FVJ4_9ASCO	53.664%	423	9.26e-121	Serine/threonine protein kinase SAK1 OS=Sugiyamaella lignohabitans GN=SAK1 PE=4 SV=1
A0A1E3PL82_9ASCO	48.000%	425	8.11e-107	Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82625 PE=4 SV=1
A0A060T510_BLAAD	66.537%	257	2.50e-103	ARAD1B00550p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B00550g PE=4 SV=1
Q6C9S1_YARLI	64.286%	266	9.10e-102	YALI0D08822p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D08822g PE=4 SV=1
A0A1E4TAY6_9ASCO	65.975%	241	2.49e-97	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13094 PE=3 SV=1
Q5A650_CANAL	48.160%	326	7.15e-79	Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3840 PE=4 SV=1
SAK1_YEAST	53.846%	286	8.10e-77	SNF1-activating kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAK1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1052

Protein family membership

None predicted.

Domains and repeats

Domain
336 - 701
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1400 1671

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  652 - 701
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  336 - 599
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  357 - 687
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. SM00220 (serkin_6)
  
  357 - 687
  
  SMART
  SM00220 (serkin_6)
3. PF00069 (Pkinase)
  
  357 - 687
  
  Pfam
  PF00069 (Pkinase)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  363 - 386
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)

no IPR

Unintegrated signatures

Coil

1,671 - 1,671

COILS
Coil (Coil)
G3DSA:1.10.51...

432 - 693

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

344 - 431

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd14008 (STKc_LKB1_...)

363 - 687

CDD
cd14008 (STKc_LKB1_CaMKK)
mobidb-lite (disord...)

878 - 931

MobiDB Lite
mobidb-lite (disorder_prediction)

1,266 - 1,337

MobiDB Lite
mobidb-lite (disorder_prediction)

948 - 1,039

MobiDB Lite
mobidb-lite (disorder_prediction)

1,511 - 1,589

MobiDB Lite
mobidb-lite (disorder_prediction)

1,052 - 1,078

MobiDB Lite
mobidb-lite (disorder_prediction)

626 - 654

MobiDB Lite
mobidb-lite (disorder_prediction)

1,628 - 1,671

MobiDB Lite
mobidb-lite (disorder_prediction)

1,378 - 1,404

MobiDB Lite
mobidb-lite (disorder_prediction)

749 - 842

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 335

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

363L

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

364G

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

365R

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

366G

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

367Q

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

371V

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

384A

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

386K

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

425V

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

442L

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

443E

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

444Y

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

445L

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

449E

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

489D

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

491K

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

493A

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

494N

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

496L

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)

507D

ATP binding site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D
CDD
cd14008 (STKc_LKB1_CaMKK)
active site cd14008

363L

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

364G

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

365R

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

366G

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

367Q

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

371V

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

384A

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

386K

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

425V

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

442L

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

443E

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

444Y

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

445L

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

449E

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

489D

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

491K

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

493A

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

494N

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

496L

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

507D

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

510V

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

531G

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

532T

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

533P

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

534A

active site
363L, 364G, 365R, 366G, 367Q, 371V, 384A, 386K, 425V, 442L, 443E, 444Y, 445L, 449E, 489D, 491K, 493A, 494N, 496L, 507D, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)
polypeptide substr...

367Q

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

449E

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

489D

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

491K

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

493A

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

510V

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

531G

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

532T

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

533P

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

534A

polypeptide substrate binding site
367Q, 449E, 489D, 491K, 493A, 510V, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)
activation loop (A...

506S

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

507D

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

508F

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

509G

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

510V

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

511S

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

512Y

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

513A

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

514S

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

515N

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

528K

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

529T

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

530A

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

531G

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

532T

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

533P

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

534A

activation loop (A-loop)
506S, 507D, 508F, 509G, 510V, 511S, 512Y, 513A, 514S, 515N, 528K, 529T, 530A, 531G, 532T, 533P, 534A
CDD
cd14008 (STKc_LKB1_CaMKK)

Protein sequence

>MIA_00922_1
MSLPKADLQDPPRPPIVRVSARHGTATQLLSSSSLATSTSSPLASTATITTADLPATTTANRNSRPHISIPPLCSSSSSA
SISTVSPPDSTPESPAIASPVPRYRSARGAGASSNNGTSTPSSIMSSSSTSSSHQQHSHKSLRSQSSKSSIFSSDIASPS
SSSSLSFMHKLSHLHHHHHNSNPPASPASNKPDLQQPPLHSLNNSQISSTPSHTRTPSACSTASSASTSTTASQKPKYTT
ASLRSPQSSIQASESLLSKHQQPSHLDPPIKLESPVPKYLHHPPSSTSSSSSALSAQIRSPSSTRTPLNELRRPSSTSSS
ASSPSMPPSPTSTSVKETNYVVIDVNPVSGRKLLNKYEIIKELGRGQHGKVKLALDTETNEFVAIKIVDRLGKPKLGRVR
PGLSHEDKVRREIAIMKKCHHPNIVNLIEVLDDSSSKIYLVLEYLERGEVHWQDADGNPALTQDQARDVARDVISGLEYL
HFQGIIHRDIKPANLLRDKNDTVKISDFGVSYASNLDANTSDEFELAKTAGTPAFFAPELCATSSPDGGPRPPITAKIDI
WAFGVTLFCLIYGKLPFSAENEFELFDVIANDPLVFPDEVPEFPVPKKKRNFHSIFYNVDASSESLADLEDEQDGQQSPP
QDDDNIERPPVVPNPALASVKDLLRKVLEKDPTKRIDLNGIKHHPWMMEGMDLPRLEHFLTETTDDQRIVVTNEDVQRAV
SGIGSRIKRGISRGLSRLGSSALHFAGLRRKGSSSSSSANPSGAPSRSVSRDAHRSPSASTIGLKSPKQGPSRSDVKARN
KKYFESSTILSSTSSGHESDYSTTSSSRFNSRKNTGNSAPNAAAAMAATGTATAINDNSLQLIDQAILSSRRSTSSSFSS
LSSLSSLQSGGPPLTWQTSNPREYQVHSHTRDKSLTGAILSRTNSNTTGVGSTTSAAVAAAASGDPAHLAHSLRSPGSLS
PTMPSPITPVMGAIPTDLGTDTRQKSATPRLTIPSFSPFRGGQLLSEDSDEESVGSGSADGVSLVMPPPTSFPARLPSSR
NNLKLHSILTDGASTGADSDDSSSACSPTQSCGPLSRKQTYTLGDYGDYYGASGYSDGYDYDDKLGTSYNSTKDNSVSMP
FHSPSNAFSSSGLATPVAGSASISGPSTMTTMTGLGPVPAAHEGSMYSTGSAISAASTSSYSTLSGLKGSSSYELPQLDV
DDADSGLFGDDERGFGDDSGLFLRKKSTSSFYQHRLSTSSGHDSLQPLSSVPESTAAPIKINALTPAHLRKGSQPTLTSS
SAASINSVSSSSSDEGGGGLTLVVERKKSNTPASMPLSENTSTSSFSRKNSLPPIPTPTYATISRLVSTPGPVTPTGPGS
VAGSGVSTPTNARFSTKFAPSTASRMSPHPTKTAATTAGFNPSPVNFNARRADSIGSTASRLSTSSGGSEVLPLPSNLAS
EMLGGGLMPLSPGFASDDMEHIVAHHTYRQPPGVSISAPMTPGRSGGSGGMVPLAYSATGGSGLAVLSSSGSGYSLHATT
SRDSTVSAGSSSSANSSSGSLVINVPRRSTNITPSSSRTSKPGNREDVKGPGDELLGRGRGPGSGAHVRSQSVAVGQVQY
HRQIVDAYKCDGSAYNYTTPGPASPVCGAGAGFCLSDSDDDDDSDNDSDGTQELQLEFGRGSSRVRSPVGK

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component